Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vasant, Jayasankar"'
Publikováno v:
Journal of Geriatric Cardiology : JGC
Autor:
Dennis E. Discher, H. Lee Sweeney, Lawrence T. Bish, Timothy J. Pirolli, Y. Joseph Woo, Kevin J. Morine, Vasant Jayasankar, Mark F. Berry, Adam J. Engler, Timothy J. Gardner
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H2196-H2203
Cellular therapy for myocardial injury has improved ventricular function in both animal and clinical studies, though the mechanism of benefit is unclear. This study was undertaken to examine the effects of cellular injection after infarction on myoca
Autor:
Y. Joseph Woo, Jeffrey Burdick, Pavan Atluri, Mark F. Berry, Suzanne Zentko, Todd J. Grand, Matthew D. Taylor, Jeffrey A. Cohen, George P. Liao, Mireille A. Moise, Timothy J. Gardner, Vivian M. Hsu, Steve Kolakowski, H. Lee Sweeney, Vasant Jayasankar, Omar Z. Fisher, Max Smith
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 130(2):321-329
ObjectiveIschemic heart failure is an increasingly prevalent global health concern with major morbidity and mortality. Currently, therapies are limited, and novel revascularization methods might have a role. This study examined enhancing endogenous m
Autor:
Omar Z. Fisher, Y. Joseph Woo, Timothy J. Pirolli, Vasant Jayasankar, Timothy J. Gardner, Kevin J. Morine, Mark F. Berry, Mireille A. Moise, Paul H. Patterson
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 128:866-875
Objective: Myocardial infarction leads to cardiomyocyte loss. The cytokine leukemia inhibitory factor regulates the differentiation and growth of embryonic and adult heart tissue. This study examined the effects of gene transfer of leukemia inhibitor
Autor:
Vasant Jayasankar, Lawrence T. Bish, Jeffrey Burdick, H. Lee Sweeney, Timothy J. Gardner, Mireille A. Moise, Y. Joseph Woo, Mark F. Berry, Timothy J. Pirolli, Kevin J. Morine
Publikováno v:
The Journal of Heart and Lung Transplantation. 23:1061-1068
Tumor necrosis factor (TNF) causes myocardial extracellular matrix remodeling and fibrosis in myocardial infarction and chronic heart failure models. Pre-clinical and clinical trials of TNF inhibition in chronic heart failure have shown conflicting r
Autor:
Vasant Jayasankar, Y. Joseph Woo, Mark F. Berry, Timothy J. Pirolli, Lawrence T. Bish, Jeffrey Burdick
Publikováno v:
The Annals of Thoracic Surgery. 77:2122-2129
Ventricular remodeling with chamber dilation and wall thinning is seen in postinfarction heart failure. Growth hormone induces myocardial hypertrophy when oversecreted. We hypothesized that localized myocardial hypertrophy induced by gene transfer of
Autor:
Y. Joseph Woo, Matthew D. Taylor, Vivian M. Hsu, Mark F. Berry, Vasant Jayasankar, Timothy J. Pirolli, Todd J. Grand, Jeffrey E. Cohen, Lawrence T. Bish, Jeffrey Burdick
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 127:1262-1269
ObjectiveMyocardial injury and dysfunction following ischemia are mediated in part by reactive oxygen species. Pyruvate, a key glycolytic intermediary, is an effective free radical scavenger but unfortunately is limited by aqueous instability. The es
Autor:
Lawrence T. Bish, Jeffrey Burdick, Y. Joseph Woo, Mark F. Berry, Timothy J. Pirolli, Vasant Jayasankar, Todd J. Grand
Publikováno v:
Journal of Molecular and Cellular Cardiology. 36:531-538
Post-infarction heart failure is characterized by progressive left ventricular dilatation and wall thinning, with both systolic and diastolic cardiac dysfunction. Human growth hormone (GH) stimulates cardiac hypertrophy when secreted in excess and di
Publikováno v:
Journal of the American College of Cardiology. 69:2446
Autor:
Y. Joseph Woo, Timothy J. Gardner, Vasant Jayasankar, Mark F. Berry, H. Lee Sweeney, Timothy J. Pirolli, T B A Lawrence Bish, Jeffrey Burdick
Publikováno v:
Journal of cardiac surgery. 20(1)
BACKGROUND Heart failure following myocardial infarction (MI) is a significant cause of morbidity and mortality and remains a difficult therapeutic challenge. Hepatocyte growth factor (HGF) is a potent angiogenic and anti-apoptotic protein whose rece