Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Vasan K, Sambandamurthy"'
Autor:
Jafar Hasan, Shubham Jain, Rinsha Padmarajan, Swathi Purighalla, Vasan K. Sambandamurthy, Kaushik Chatterjee
Publikováno v:
Materials & Design, Vol 140, Iss , Pp 332-344 (2018)
Toward minimizing bacterial colonization of surfaces, we present a one-step etching technique that renders aluminum alloys with micro- and nano-scale roughness. Such a multi-scale surface topography exhibited enhanced antibacterial effect against a w
Externí odkaz:
https://doaj.org/article/6a965e510ea843399278041c686f8b5d
Autor:
Sudha Ravishankar, Anisha Ambady, Rayapadi G Swetha, Anand Anbarasu, Sudha Ramaiah, Vasan K Sambandamurthy
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147188 (2016)
Discovery of mupirocin, an antibiotic that targets isoleucyl-tRNA synthetase, established aminoacyl-tRNA synthetase as an attractive target for the discovery of novel antibacterial agents. Despite a high degree of similarity between the bacterial and
Externí odkaz:
https://doaj.org/article/718ea10aaf3841ba8b86824ea7821a87
Autor:
Sudha Ravishankar, Anisha Ambady, Haripriya Ramu, Naina Vinay Mudugal, Ragadeepthi Tunduguru, Anand Anbarasu, Umender K Sharma, Vasan K Sambandamurthy, Sudha Ramaiah
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134562 (2015)
Conditional expression strains serve as a valuable tool to study the essentiality and to establish the vulnerability of a target under investigation in a drug discovery program. While essentiality implies an absolute requirement of a target function,
Externí odkaz:
https://doaj.org/article/ffd5bfe858b04a29be5bafb13d0f0e00
Autor:
Paul Murima, Paola Florez de Sessions, Vivian Lim, Ahmad Nazri Mohamed Naim, Pablo Bifani, Helena I M Boshoff, Vasan K Sambandamurthy, Thomas Dick, Martin L Hibberd, Mark Schreiber, Srinivasa P S Rao
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69191 (2013)
Most candidate anti-bacterials are identified on the basis of their whole cell anti-bacterial activity. A critical bottleneck in the early discovery of novel anti-bacterials is tracking the structure activity relationship (SAR) of the novel compounds
Externí odkaz:
https://doaj.org/article/42cf5d8b81aa4f868992f0e05773d906
Autor:
Prosenjit Sen, Arvind Kumar, Abinash Tripathy, Atish Roy Chowdhury, Kapudeep Karmakar, Dipshikha Chakravortty, Vasan K. Sambandamurthy, Swathi Purighalla
Publikováno v:
ACS Applied Nano Materials. 1:2678-2688
The global emergence of antimicrobial resistance poses a serious risk to patients by increasing the cost of healthcare with prolonged stay in hospitals, serious clinical complications, and even death. The ever-increasing challenges in discovering ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d617c5962f31699e6be7a836a599219
https://doi.org/10.1021/acsanm.8b00397
https://doi.org/10.1021/acsanm.8b00397
Autor:
Vijay S Richard, Swathi Purighalla, George Varghese, Sarita Esakimuthu, Mallika P Reddy, Vasan K. Sambandamurthy
Publikováno v:
Indian Journal of Medical Microbiology, Vol 35, Iss 3, Pp 361-368 (2017)
Purpose: The purpose of this study was to evaluate the discriminatory power of two DNA-based technique and a protein-based technique for the typing of nosocomial isolates of Klebsiella pneumoniae. A second objective was to determine the antimicrobial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6667c6ace96531ecc43dfdf5197a9978
https://doi.org/10.4103/ijmm.ijmm_16_308
https://doi.org/10.4103/ijmm.ijmm_16_308
Autor:
Vijender Panduga, Manoranjan Panda, Radha Shandil, Shridhar Narayanan, Naveen Kumar, M Sreenivasaiah, Monalisa Chatterji, Pravin S. Shirude, Claire Sadler, Vasan K. Sambandamurthy, Tommasi Ruben A, Supreeth Guptha, Jyothi Mahadevaswamy, Meenakshi Mallya, Pravin Iyer, Sreevalli Sharma, Vasanthi Ramachandran, Christopher B. Cooper, Anisha Ambady, Ashwini Narayan, Manjunatha M R, Khisi Mdluli, Scott Butler
Publikováno v:
ACS Med Chem Lett
[Image: see text] We report a novel benzimidazole (BI) based DprE1 inhibitor that resulted from scaffold morphing of a 1,4-azaindole series. The clinical progression of the 1,4-azaindole series from our previous work validates the potential of explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b71f372de8efaf8c813fc8efd7644ae
https://pubmed.ncbi.nlm.nih.gov/31620237
https://pubmed.ncbi.nlm.nih.gov/31620237
Autor:
Manoranjan Panda, Anandkumar Raichurkar, Neela Dinesh, Vinayak Hosagrahara, Naveen Kumar, K.R. Prabhakar, Suresh Rudrapatna, Gayathri Balakrishnan, Amit K. Gupta, Vasan K. Sambandamurthy, Karthikeyan Kandaswamy, Stefan Kavanagh, Ramanatha Saralaya, Lalit kumar Jena, Shridhar Narayanan, Suresh Solapure, Robert Nanduri, V. Balasubramanian, Meenakshi Mallya, Ashwini Narayan, Sowmya Bharath, Vijender Panduga, Vikas Shinde, Jitendar Reddy, Khisi Mdluili, Christopher B. Cooper, Parvinder Kaur, Shahul Hameed P, Sreevalli Sharma, Supreeth Guptha, Kakoli Mukherjee, Sudha Ravishankar, Radha Shandil, Pravin Iyer, Shankar D. Markad, Vasanthi Ramachandran, Takahiro Yano, Jyothi Bhat, Harvey Rubin, Subramanyam J. Tantry
Publikováno v:
MedChemComm. 7:1022-1032
The success of bedaquiline as an anti-tubercular agent for the treatment of multidrug-resistant tuberculosis has validated the ATP synthesis pathway and in particular ATP synthase as an attractive target. However, limitations associated with its use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9536266d79924c4362a14dae6582a0
https://doi.org/10.1039/c5md00589b
https://doi.org/10.1039/c5md00589b
Autor:
Vaishali Humnabadkar, Claire Sadler, Tanjore S. Balganesh, Prakash Vachaspati, Disha Awasthy, Manoranjan Panda, Mick D. Fellows, Parvinder Kaur, Stewart T. Cole, Florence Pojer, Vasan K. Sambandamurthy, João Neres, Sreevalli Sharma, V. Balasubramanian, Kannan Murugan, Meenakshi Mallya, Suresh Rudrapatna, Balachandra Bandodkar, Sudhir Landge, Bheemarao G. Ugarkar, Jyothi Mahadevaswamy, Kavitha Nagalapur, Amrita B. Mullick, Vasanthi Ramachandran, Anirban Ghosh, Venkita Subbulakshmi
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:7694-7710
We report the discovery of benzothiazoles, a novel anti-mycobacterial series, identified from a whole cell based screening campaign. Benzothiazoles exert their bactericidal activity against Mycobacterium tuberculosis (Mtb) through potent inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d84f5aa2e5195a52048dc8416022f28
https://doi.org/10.1016/j.bmc.2015.11.017
https://doi.org/10.1016/j.bmc.2015.11.017
Autor:
Shubham Jain, Swathi Purighalla, Jafar Hasan, Rinsha Padmarajan, Kaushik Chatterjee, Vasan K. Sambandamurthy
Publikováno v:
Materials & Design, Vol 140, Iss, Pp 332-344 (2018)
Materials & Design
Materials & Design
Toward minimizing bacterial colonization of surfaces, we present a one-step etching technique that renders aluminum alloys with micro- and nano-scale roughness. Such a multi-scale surface topography exhibited enhanced antibacterial effect against a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e697fe6121c961dcd33d4ae418b261f5
http://eprints.iisc.ac.in/59118/1/Mat-Des_140_332_2018.pdf
http://eprints.iisc.ac.in/59118/1/Mat-Des_140_332_2018.pdf