Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Varunika Vivekanandan"'
Autor:
Devika Salunke, Elma Zaganjor, Yusuke Mizukami, Varunika Vivekanandan, Marcia C. Haigis, Leif W. Ellisen, Athena L. Chen, Sarah Jeanfavre, Nabeel Bardeesy, Kenneth N. Ross, Clary B. Clish, Sridhar Ramaswamy, Shuxi Qiao, Mari Mino-Kenudson, Siang-Boon Koh, Krushna C. Patra
Publikováno v:
Genes & Development. 34:751-766
Human cancers with activating RAS mutations are typically highly aggressive and treatment-refractory, yet RAS mutation itself is insufficient for tumorigenesis, due in part to profound metabolic stress induced by RAS activation. Here we show that los
Autor:
Ravindra Mylavagnanam, Sridhar Ramaswamy, Elena Zarcaro, Srinivas Vinod Saladi, Andrea Desmond, Murat Yildirim, Varunika Vivekanandan, Michael S. Lawrence, Kenneth N. Ross, Mihriban Karaayvaz-Yildirim, Rebecca E. Silberman, Adam Langenbucher, Leif W. Ellisen, Angelika Amon, Michelle C. Specht, Hiranmayi Ravichandran
Publikováno v:
Science Advances. 6
Women harboring heterozygous germline mutations of BRCA2 have a 50 to 80% risk of developing breast cancer, yet the pathogenesis of these cancers is poorly understood. To reveal early steps in BRCA2-associated carcinogenesis, we analyzed sorted cell
Autor:
Shuxi, Qiao, Siang-Boon, Koh, Varunika, Vivekanandan, Devika, Salunke, Krushna Chandra, Patra, Elma, Zaganjor, Kenneth, Ross, Yusuke, Mizukami, Sarah, Jeanfavre, Athena, Chen, Mari, Mino-Kenudson, Sridhar, Ramaswamy, Clary, Clish, Marcia, Haigis, Nabeel, Bardeesy, Leif W, Ellisen
Publikováno v:
Genes Dev
Human cancers with activating RAS mutations are typically highly aggressive and treatment-refractory, yet RAS mutation itself is insufficient for tumorigenesis, due in part to profound metabolic stress induced by RAS activation. Here we show that los
Autor:
Michelle C. Specht, Murat Yildirim, Michael S. Lawrence, Mihriban Karaayvaz, Srinivas Vinod Saladi, Angelika Amon, Adam Langenbucher, Rebecca E. Silberman, Varunika Vivekanandan, Andrea Desmond, Leif W. Ellisen, Sridhar Ramaswamy, Kenneth N. Ross, Ravindra Mylavagnanam, Elena Zarcaro, Hiranmayi Ravichandran
Women harboring heterozygous germline mutations of BRCA2 have a 50-80% risk of developing breast cancer, yet the early pathogenesis of these cancers is poorly understood. We sought to reveal early steps in BRCA2-associated carcinogenesis through anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7aca1536bb1e9698d683f92a1ea1e17
https://doi.org/10.1101/729301
https://doi.org/10.1101/729301
Autor:
Mihriban, Karaayvaz-Yildirim, Rebecca E, Silberman, Adam, Langenbucher, Srinivas Vinod, Saladi, Kenneth N, Ross, Elena, Zarcaro, Andrea, Desmond, Murat, Yildirim, Varunika, Vivekanandan, Hiranmayi, Ravichandran, Ravindra, Mylavagnanam, Michelle C, Specht, Sridhar, Ramaswamy, Michael, Lawrence, Angelika, Amon, Leif W, Ellisen
Publikováno v:
Science Advances
Normal breast epithelia from BRCA2 mutation carriers display DNA damage and attenuated checkpoint responses.
Women harboring heterozygous germline mutations of BRCA2 have a 50 to 80% risk of developing breast cancer, yet the pathogenesis of thes
Women harboring heterozygous germline mutations of BRCA2 have a 50 to 80% risk of developing breast cancer, yet the pathogenesis of thes
Publikováno v:
Translational cancer research. 5(6)
The tumor suppressor p53 plays a central role in safeguarding cellular homeostasis. Upon various types of stress signals such as DNA damage or oncogenic stress, p53 is promptly activated to prevent and repair damages that can threaten the genome stab