Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Varuna Nangia"'
Autor:
Eric T Clambey, Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Sana D Karam, Michael W Knitz, Ayman J Oweida, Adam C Mueller, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Beth A Jirón Tamburini, Edward D Chan, Curtis R Pickering
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background Numerous trials combining radiation therapy (RT) and immunotherapy in head and neck squamous cell carcinoma (HNSCC) are failing. Using preclinical immune cold models of HNSCC resistant to RT-immune checkpoint inhibitors, we investigate the
Externí odkaz:
https://doaj.org/article/cbf79a9cbfcd4744b19d4b8a1b088264
Autor:
Aaron N. Hata, Paul E. Hughes, Cyril H. Benes, Angela Coxon, Sean P. Brown, Kristopher A. Sarosiek, Justin F. Gainor, Christopher G. Azzoli, Anna F. Farago, Zofia Piotrowska, Lecia V. Sequist, Colleen Keyes, John H. Shin, Daniel P. Cahill, Kevin A. Raskin, Cameron D. Wright, Michael Lanuti, Lorin A. Ferris, Kristof Vajda, Diamanda Rigas, Cameron Fraser, Chendi Li, Hannah L. Archibald, Maria Gomez-Caraballo, Nicole Phan, Samantha J. Bilton, Daria Timonina, Sean Caenepeel, Faria M. Siddiqui, Varuna Nangia
BH3 mimetic drugs, which inhibit prosurvival BCL2 family proteins, have limited single-agent activity in solid tumor models. The potential of BH3 mimetics for these cancers may depend on their ability to potentiate the apoptotic response to chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70abe6bdd9a6b3e57487dfcfd1b546b5
https://doi.org/10.1158/2159-8290.c.6547298.v1
https://doi.org/10.1158/2159-8290.c.6547298.v1
Autor:
Lecia V. Sequist, Aaron N. Hata, Beni Wolf, Sai-Hong I. Ou, Corinne Clifford, Erica K. Evans, Alice T. Shaw, Rebecca S. Heist, A. John Iafrate, Mari Mino-Kenudson, Dora Dias-Santagata, Richard B. Lanman, Rebecca J. Nagy, Jessica J. Lin, Varuna Nangia, Amanda K. Riley, Satoshi Yoda, Wenjia Su, Subba R. Digumarthy, Mandeep K. Banwait, Nicolas Marcoux, Viola W. Zhu, Inga T. Lennes, Justin F. Gainor, Jochen K. Lennerz, Hideko Isozaki, Zofia Piotrowska
Supplementary Data and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc96358440634edc76f9afcf0d045e29
https://doi.org/10.1158/2159-8290.22534325.v1
https://doi.org/10.1158/2159-8290.22534325.v1
Autor:
Aaron N. Hata, Paul E. Hughes, Cyril H. Benes, Angela Coxon, Sean P. Brown, Kristopher A. Sarosiek, Justin F. Gainor, Christopher G. Azzoli, Anna F. Farago, Zofia Piotrowska, Lecia V. Sequist, Colleen Keyes, John H. Shin, Daniel P. Cahill, Kevin A. Raskin, Cameron D. Wright, Michael Lanuti, Lorin A. Ferris, Kristof Vajda, Diamanda Rigas, Cameron Fraser, Chendi Li, Hannah L. Archibald, Maria Gomez-Caraballo, Nicole Phan, Samantha J. Bilton, Daria Timonina, Sean Caenepeel, Faria M. Siddiqui, Varuna Nangia
Supplementary Figure 1-5, Supplementary Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d14dcf58051aa128a6d420a7ae16b05
https://doi.org/10.1158/2159-8290.22533896.v1
https://doi.org/10.1158/2159-8290.22533896.v1
Autor:
Lecia V. Sequist, Aaron N. Hata, Beni Wolf, Sai-Hong I. Ou, Corinne Clifford, Erica K. Evans, Alice T. Shaw, Rebecca S. Heist, A. John Iafrate, Mari Mino-Kenudson, Dora Dias-Santagata, Richard B. Lanman, Rebecca J. Nagy, Jessica J. Lin, Varuna Nangia, Amanda K. Riley, Satoshi Yoda, Wenjia Su, Subba R. Digumarthy, Mandeep K. Banwait, Nicolas Marcoux, Viola W. Zhu, Inga T. Lennes, Justin F. Gainor, Jochen K. Lennerz, Hideko Isozaki, Zofia Piotrowska
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e051601bd88ba6af4840dc715298fa
https://doi.org/10.1158/2159-8290.22534322.v1
https://doi.org/10.1158/2159-8290.22534322.v1
Autor:
Cyril H. Benes, Aaron N. Hata, Yi Liu, Lian-Sheng Li, Matthew R. Janes, Patrick P. Zarrinkar, Ellen Murchie, Giovanna T. Stein, Joseph McClanaghan, Regina K. Egan, Patricia Greninger, Varuna Nangia, Max Greenberg, Maria Gomez-Caraballo, Dana Lee, David T. Myers, Daria Timonina, Samantha Bilton, Chendi Li, Eliane Cortez, Jackson P. Fatherree, Sandra Misale
Supplementary Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6002e1de0b9fa72e7c7ac907e910c7
https://doi.org/10.1158/1078-0432.22475831.v1
https://doi.org/10.1158/1078-0432.22475831.v1
Autor:
Cyril H. Benes, Aaron N. Hata, Yi Liu, Lian-Sheng Li, Matthew R. Janes, Patrick P. Zarrinkar, Ellen Murchie, Giovanna T. Stein, Joseph McClanaghan, Regina K. Egan, Patricia Greninger, Varuna Nangia, Max Greenberg, Maria Gomez-Caraballo, Dana Lee, David T. Myers, Daria Timonina, Samantha Bilton, Chendi Li, Eliane Cortez, Jackson P. Fatherree, Sandra Misale
Purpose:KRAS-mutant lung cancers have been recalcitrant to treatments including those targeting the MAPK pathway. Covalent inhibitors of KRAS p.G12C allele allow for direct and specific inhibition of mutant KRAS in cancer cells. However, as for other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8066f1e76350109a82cce15e9ec86925
https://doi.org/10.1158/1078-0432.c.6529181
https://doi.org/10.1158/1078-0432.c.6529181
Autor:
Cyril H. Benes, Aaron N. Hata, Yi Liu, Lian-Sheng Li, Matthew R. Janes, Patrick P. Zarrinkar, Ellen Murchie, Giovanna T. Stein, Joseph McClanaghan, Regina K. Egan, Patricia Greninger, Varuna Nangia, Max Greenberg, Maria Gomez-Caraballo, Dana Lee, David T. Myers, Daria Timonina, Samantha Bilton, Chendi Li, Eliane Cortez, Jackson P. Fatherree, Sandra Misale
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5a896d86ec7e50b167343ffefbbee1
https://doi.org/10.1158/1078-0432.22475804
https://doi.org/10.1158/1078-0432.22475804
Autor:
Cyril H. Benes, Aaron N. Hata, Yi Liu, Lian-Sheng Li, Matthew R. Janes, Patrick P. Zarrinkar, Ellen Murchie, Giovanna T. Stein, Joseph McClanaghan, Regina K. Egan, Patricia Greninger, Varuna Nangia, Max Greenberg, Maria Gomez-Caraballo, Dana Lee, David T. Myers, Daria Timonina, Samantha Bilton, Chendi Li, Eliane Cortez, Jackson P. Fatherree, Sandra Misale
Supplementary Data 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8981c3aa5fb4c0430aeb921e3817508c
https://doi.org/10.1158/1078-0432.22475837
https://doi.org/10.1158/1078-0432.22475837
Autor:
Cyril H. Benes, Aaron N. Hata, Yi Liu, Lian-Sheng Li, Matthew R. Janes, Patrick P. Zarrinkar, Ellen Murchie, Giovanna T. Stein, Joseph McClanaghan, Regina K. Egan, Patricia Greninger, Varuna Nangia, Max Greenberg, Maria Gomez-Caraballo, Dana Lee, David T. Myers, Daria Timonina, Samantha Bilton, Chendi Li, Eliane Cortez, Jackson P. Fatherree, Sandra Misale
Legends to supplementary table, data and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65be45ec87ff83645f8cc9d3a1cb130a
https://doi.org/10.1158/1078-0432.22475807.v1
https://doi.org/10.1158/1078-0432.22475807.v1