Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Varun Sahu"'
Autor:
Xiao Chen, Yinglu Li, Fang Zhu, Xinjing Xu, Brian Estrella, Manuel A. Pazos, John T. McGuire, Dimitris Karagiannis, Varun Sahu, Mustafo Mustafokulov, Claudio Scuoppo, Francisco J. Sánchez-Rivera, Yadira M. Soto-Feliciano, Laura Pasqualucci, Alberto Ciccia, Jennifer E. Amengual, Chao Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Interplay between chromatin-associated complexes and modifications critically contribute to the partitioning of epigenome into stable and functionally distinct domains. Yet there is a lack of systematic identification of chromatin crosstalk
Externí odkaz:
https://doaj.org/article/daa06f01dba548f4b57a4bb4e1ae71da
Autor:
Malay K. Sannigrahi, Pavithra Rajagopalan, Ling Lai, Xinyi Liu, Varun Sahu, Hiroshi Nakagawa, Jalal B. Jalaly, Robert M. Brody, Iain M. Morgan, Bradford E. Windle, Xiaowei Wang, Phyllis A. Gimotty, Daniel P. Kelly, Elizabeth A. White, Devraj Basu
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Therapy with radiation plus cisplatin kills HPV+ oropharyngeal squamous cell carcinomas (OPSCCs) by increasing reactive oxygen species beyond cellular antioxidant capacity. To explore why these standard treatments fail for some patients, we evaluated
Externí odkaz:
https://doaj.org/article/2e2a2366ebb445348cb086698c1327da
Autor:
Takashi Kijima, Hiroshi Nakagawa, Masataka Shimonosono, Prasanna M. Chandramouleeswaran, Takeo Hara, Varun Sahu, Yuta Kasagi, Osamu Kikuchi, Koji Tanaka, Veronique Giroux, Amanda B. Muir, Kelly A. Whelan, Shinya Ohashi, Seiji Naganuma, Andres J. Klein-Szanto, Yoshiaki Shinden, Ken Sasaki, Itaru Omoto, Yoshiaki Kita, Manabu Muto, Adam J. Bass, J. Alan Diehl, Gregory G. Ginsberg, Yuichiro Doki, Masaki Mori, Yasuto Uchikado, Takaaki Arigami, Narayan G. Avadhani, Devraj Basu, Anil K. Rustgi, Shoji Natsugoe
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims: Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thr
Externí odkaz:
https://doaj.org/article/7488edc6ab024bcda04958703e1f2938
Autor:
Mitsuteru Natsuizaka, Kelly A. Whelan, Shingo Kagawa, Koji Tanaka, Veronique Giroux, Prasanna M. Chandramouleeswaran, Apple Long, Varun Sahu, Douglas S. Darling, Jianwen Que, Yizeng Yang, Jonathan P. Katz, E. Paul Wileyto, Devraj Basu, Yoshiaki Kita, Shoji Natsugoe, Seiji Naganuma, Andres J. Klein-Szanto, J. Alan Diehl, Adam J. Bass, Kwok-Kin Wong, Anil K. Rustgi, Hiroshi Nakagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Notch receptors can exert different roles in cancer. In this manuscript, the authors reveal that Notch1 activation and EMT promote tumor initiation and cancer cell heterogeneity in squamous cell carcinoma, while the repression of Notch3 by ZEB1 limit
Externí odkaz:
https://doaj.org/article/6f8691ad6d324ab0a967f60181be89c5
Autor:
Karen J. Dunbar, Tatiana A. Karakasheva, Qiaosi Tang, Gizem Efe, Eric W. Lin, Michael Harris, Varun Sahu, Uma M. Sachdeva, Jianhua Hu, Andres J. Klein-Szanto, Brian Henick, J. Alan Diehl, Hiroshi Nakagawa, Anil K. Rustgi
Publikováno v:
Molecular Cancer Research. :OF1-OF12
Cancer-associated fibroblasts (CAF) can promote tumor growth, metastasis, and therapeutic resistance in esophageal squamous cell carcinoma (ESCC), but the mechanisms of action remain elusive. Our objective was to identify secreted factor(s) that medi
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Targeted CCR5 inhibition replicates CCL5 loss with reduced tumor cell proliferation in vitro and in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a3d3e670567eb8f1f072c3d48d8f7
https://doi.org/10.1158/1541-7786.22700254
https://doi.org/10.1158/1541-7786.22700254
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
ERK1/2 signaling pathway in CCL5 knockout cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0933bb1734d9093ebae053c064ff7727
https://doi.org/10.1158/1541-7786.22700257
https://doi.org/10.1158/1541-7786.22700257
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Loss of tumor-derived CCL5 reduces tumor cell proliferation in TE-1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce5da3b6e41b4c3241494e7d8a6d482
https://doi.org/10.1158/1541-7786.22700260
https://doi.org/10.1158/1541-7786.22700260
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Supplementary Figure Legends 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4fc845773602170d8f1371eb13a554
https://doi.org/10.1158/1541-7786.22700251
https://doi.org/10.1158/1541-7786.22700251
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Cancer-associated fibroblasts (CAF) can promote tumor growth, metastasis, and therapeutic resistance in esophageal squamous cell carcinoma (ESCC), but the mechanisms of action remain elusive. Our objective was to identify secreted factor(s) that medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea27b6630d56cd1b5ec63faa125b304
https://doi.org/10.1158/1541-7786.c.6618025.v1
https://doi.org/10.1158/1541-7786.c.6618025.v1