Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Varun Bahl"'
Autor:
Minghui Wu, Michelle Y.Y. Lee, Varun Bahl, Daniel Traum, Jonathan Schug, Irina Kusmartseva, Mark A. Atkinson, Guanjie Fan, Klaus H. Kaestner
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109919- (2021)
Summary: Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglycemia due to the failure of pancreatic beta cells to compensate for increased insulin demand. Despite decades of research, the pathogenic mechanisms un
Externí odkaz:
https://doaj.org/article/a8c0452dd1184df08e2878403748613b
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101193- (2021)
Objective: While the molecular events controlling insulin secretion from β-cells have been documented in detail, the exact mechanisms governing glucagon release by α-cells are understood only partially. This is a critical knowledge gap, as the norm
Externí odkaz:
https://doaj.org/article/837754ad260f4f72819b813c7936915a
Publikováno v:
Diabetes. 71
The G6PC2 locus, encoding the catalytic subunit of the islet-specific glucose-6-phosphatase enzyme, is an established risk locus for HbA1c and fasting glucose levels. A critical role of glycolytic flux in regulating glucagon secretion was established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d152e05f1048050f421ea205a6960f4f
https://doi.org/10.2337/db22-229-lb
https://doi.org/10.2337/db22-229-lb
Autor:
Jonathan Schug, Varun Bahl, Minghui Wu, Klaus H. Kaestner, Michelle Y.Y. Lee, Daniel Traum, Mark A. Atkinson, Guanjie Fan, Irina Kusmartseva
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109919-(2021)
Cell reports
Cell reports
SUMMARY Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglycemia due to the failure of pancreatic beta cells to compensate for increased insulin demand. Despite decades of research, the pathogenic mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405dcc2ecba3a118152924f492de50f4
http://www.sciencedirect.com/science/article/pii/S2211124721013929
http://www.sciencedirect.com/science/article/pii/S2211124721013929
Publikováno v:
Molecular Metabolism, Vol 49, Iss, Pp 101193-(2021)
Molecular Metabolism
Molecular Metabolism
Objective While the molecular events controlling insulin secretion from β-cells have been documented in detail, the exact mechanisms governing glucagon release by α-cells are understood only partially. This is a critical knowledge gap, as the norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a321c33d9157f31ec647cb80b3e219fe
http://www.sciencedirect.com/science/article/pii/S2212877821000338
http://www.sciencedirect.com/science/article/pii/S2212877821000338
Autor:
Young Moon, Varun Bahl
Publikováno v:
Syracuse University Experts@Syracuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5d9b67e4e45ce18a24404d4457a699ea
https://experts.syr.edu/en/publications/c91e4e58-bba9-430c-8bd7-f4230300e913
https://experts.syr.edu/en/publications/c91e4e58-bba9-430c-8bd7-f4230300e913
