Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Varun, Dwivedi"'
Autor:
Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Alyssa Schami, Susan Weintraub, Philip S. Tsao, Jordi B. Torrelles, Joanne Turner
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is a major global health concern, particularly affecting those with weakened immune systems, including the elderly. CD4+ T cell response is crucial for immunity against M.tb, bu
Externí odkaz:
https://doaj.org/article/0dd086a82df94a179d0e656b797beb92
Autor:
Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Anwari Akhter, Alyssa Schami, Kevin Chiem, Russell Ault, Hao Zhang, Hong Cai, Alison Whigham, Jennifer Delgado, Amberlee Hicks, Philip S. Tsao, Jonathan Gelfond, Luis Martinez‐Sobrido, Yufeng Wang, Jordi B. Torrelles, Joanne Turner
Publikováno v:
Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)
Abstract Mitochondrial dysfunction alters cellular metabolism, increases tissue oxidative stress, and may be principal to the dysregulated signaling and function of CD4+ T lymphocytes in the elderly. In this proof of principle study, it is investigat
Externí odkaz:
https://doaj.org/article/155b08ee8fdd4021bcf7f433c2bfd1c0
Autor:
Fatai S. Oladunni, Jun-Gyu Park, Paula A. Pino, Olga Gonzalez, Anwari Akhter, Anna Allué-Guardia, Angélica Olmo-Fontánez, Shalini Gautam, Andreu Garcia-Vilanova, Chengjin Ye, Kevin Chiem, Colwyn Headley, Varun Dwivedi, Laura M. Parodi, Kendra J. Alfson, Hilary M. Staples, Alyssa Schami, Juan I. Garcia, Alison Whigham, Roy Neal Platt, Michal Gazi, Jesse Martinez, Colin Chuba, Stephanie Earley, Oscar H. Rodriguez, Stephanie Davis Mdaki, Katrina N. Kavelish, Renee Escalona, Cory R. A. Hallam, Corbett Christie, Jean L. Patterson, Tim J. C. Anderson, Ricardo Carrion, Edward J. Dick, Shannan Hall-Ursone, Larry S. Schlesinger, Xavier Alvarez, Deepak Kaushal, Luis D. Giavedoni, Joanne Turner, Luis Martinez-Sobrido, Jordi B. Torrelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here, the authors characterize tissue-level SARS-CoV-2 infection and pathogenesis in transgenic mice expressing human angiotensin converting enzyme 2 (hACE2) by the human cytokeratin 18 promoter (K18-hACE2) and show that infection induces lethality,
Externí odkaz:
https://doaj.org/article/36d6d32972464a4aafa1c9bc19844493
Autor:
Caleb D. Swaim, Varun Dwivedi, Yi-Chieh Perng, Xu Zhao, Larissa A. Canadeo, Houda H. Harastani, Tamarand L. Darling, Adrianus C.M. Boon, Deborah J. Lenschow, Viraj Kulkarni, Jon M. Huibregtse
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103213- (2021)
Summary: The emergence of SARS-CoV-2 has led to a global health crisis that, in addition to vaccines and immunomodulatory therapies, calls for the identification of antiviral therapeutics. The papain-like protease (PLpro) activity of nsp3 is an attra
Externí odkaz:
https://doaj.org/article/2d628d8bb0d24099b4370a53d4b95c2c
Autor:
Kenneth S. Plante, Varun Dwivedi, Jessica A. Plante, Diana Fernandez, Divya Mirchandani, Nathen Bopp, Patricia V. Aguilar, Jun-Gyu Park, Paula Pino Tamayo, Jennifer Delgado, Vinay Shivanna, Jordi B. Torrelles, Luis Martinez-Sobrido, Rick Matos, Scott C. Weaver, K. Jagannadha Sastry, Robert A. Newman
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111457- (2021)
With continued expansion of the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), both antiviral drugs as well as effective vaccines are desperately needed to treat patients at high risk of life-thre
Externí odkaz:
https://doaj.org/article/dda910ba45da4435882993e51252c403
Autor:
Abhinandan Mani Tripathi, Rajneesh Singh, Ashwani Kumar Verma, Akanksha Singh, Parneeta Mishra, Varun Dwivedi, Shiv Narayan, Vivek Hari Sundar Gandhivel, Pramod Arvind Shirke, Padubidri V. Shivaprasad, Sribash Roy
Publikováno v:
The Plant Journal. 114:855-874
Autor:
Varun Dwivedi, Shalini Gautam, Colwyn A. Headley, Tucker Piergallini, Jordi B. Torrelles, Joanne Turner
Publikováno v:
The Journal of Immunology. 208:1406-1416
Mycobacterium bovis bacillus Calmette–Guérin (BCG) immunization still remains the best vaccination strategy available to control the development of active tuberculosis. Protection afforded by BCG vaccination gradually wanes over time and although
Autor:
Seema Meena, Sarma Rajeevkumar, DK Venkata Rao, Varun Dwivedi, HB Shilpashree, Shubhra Rastogi, Ajit Kumar Shasany, Dinesh A Nagegowda
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Aromatic grasses of the genus Cymbopogon (Poaceae family) represent unique group of plants that produce diverse composition of monoterpene rich essential oils, which have great value in flavour, fragrance, cosmetic and aromatherapy industries. Despit
Externí odkaz:
https://doaj.org/article/b2687c27f61e45178f5227fce3f961c6
Autor:
Joanne Trgovcich, Michelle Kincaid, Alicia Thomas, Marion Griessl, Peter Zimmerman, Varun Dwivedi, Valerie Bergdall, Paul Klenerman, Charles H Cook
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167097 (2016)
Cytomegalovirus (CMV) has been shown to induce large populations of CD8 T-effector memory cells that unlike central memory persist in large quantities following infection, a phenomenon commonly termed "memory inflation". Although murine models to dat
Externí odkaz:
https://doaj.org/article/e60f78e315ab4ba0876ac49a87c89392
Autor:
Shannon B. Olsson, Dinesh A. Nagegowda, Pragadheesh V. Shanmugam, Varun Dwivedi, Dikki Pedenla Bomzan, Sarma Rajeev Kumar, Srinivas Rao
Publikováno v:
Physiologia Plantarum. 171:7-21
Terpene synthases (TPSs) produce a variety of terpenoids that play numerous functional roles in primary and secondary metabolism, as well as in ecological interactions. Here, we report the functional characterization of an inducible potato TPS gene e