Opioid Use Disorder Treatment in the Fentanyl Era.

Autor: Varshneya NB, Thakrar AP, Lambert E, Huhn AS

Publikováno v: Journal of addiction medicine [J Addict Med] 2023 Jan-Feb 01; Vol. 17 (1), pp. 118-119. Date of Electronic Publication: 2022 Jul 20.

Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner.

Autor: Elder HJ; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Varshneya NB; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Center for Drug Evaluation and Research, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, USA., Walentiny DM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Beardsley PM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Center for Biomarker Research & Precision Medicine, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA. Electronic address: patrick.beardsley@vcuhealth.org.

Publikováno v: Drug and alcohol dependence [Drug Alcohol Depend] 2023 Feb 01; Vol. 243, pp. 109740. Date of Electronic Publication: 2022 Dec 16.

Structurally diverse fentanyl analogs yield differential locomotor activities in mice.

Autor: Varshneya NB; Center for Drug Evaluation and Research, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, USA; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. Electronic address: nvarshn2@jhmi.edu., Walentiny DM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Stevens DL; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Walker TD; Diversion Control Division, Drug Enforcement Administration, United States Department of Justice, Springfield, VA, USA., Akinfiresoye LR; Diversion Control Division, Drug Enforcement Administration, United States Department of Justice, Springfield, VA, USA., Beardsley PM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Center for Biomarker Research & Precision Medicine, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.

Publikováno v: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2023 Jan; Vol. 222, pp. 173496. Date of Electronic Publication: 2022 Nov 24.

Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated.

Autor: Varshneya NB; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. Electronic address: nvarshn2@jhmi.edu., Hassanien SH; Forensic Chemistry Division, Cayman Chemical Company, Ann Arbor, MI, USA., Holt MC; Forensic Chemistry Division, Cayman Chemical Company, Ann Arbor, MI, USA., Stevens DL; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Layle NK; Forensic Chemistry Division, Cayman Chemical Company, Ann Arbor, MI, USA., Bassman JR; Forensic Chemistry Division, Cayman Chemical Company, Ann Arbor, MI, USA., Iula DM; Forensic Chemistry Division, Cayman Chemical Company, Ann Arbor, MI, USA., Beardsley PM; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA; Center for Biomarker Research & Precision Medicine, Virginia Commonwealth University School of Pharmacy, Richmond, VA, USA.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2022 Jan; Vol. 195, pp. 114805. Date of Electronic Publication: 2021 Oct 19.

Improving Translational Research Outcomes for Opioid Use Disorder Treatments.

Autor: Jones JD; Division on Substance Use Disorders, Department of Psychiatry, New York State Psychiatric Institute, and Columbia University Irving Medical Center, 1051 Riverside Drive, New York, NY 10032, USA., Varshneya NB; Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, 410 N 12th St, Richmond, VA 23298, USA.; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA., Hudzik TJ; In Vitro In Vivo Translation, NonClinical Safety, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA 19426, USA., Huhn AS; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA.

Publikováno v: Current addiction reports [Curr Addict Rep] 2021 Mar; Vol. 8 (1), pp. 109-121. Date of Electronic Publication: 2021 Jan 12.