Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Varshaver NB"'
Publikováno v:
Cancer genetics and cytogenetics. 62(1)
The induction of gene mutations and chromosome aberrations by plasmid pEJ6.6 carrying the activated c-Ha- ras -1 oncogene from human bladder carcinoma was studied in cultured Chinese hamster cells. Both an increase in the frequency of hypoxanthine-ph
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Publikováno v:
International Journal of Cancer. 31:471-475
The genetic mechanisms determining the ability of transformed cells to grow in a medium with a low serum content (ser+) were studied in a clone of Chinese hamster cells with normal serum requirements. The fluctuation test has shown that serum indepen
Publikováno v:
Somatic Cell Genetics. 7:133-146
Oncogenic bovine adenovirus (BAV3) was shown to induce chromosome aberrations and gene mutations to 6-mercaptopurine (6MP) resistance in Chinese hamster cells. BAV3 showed the highest mutagenic effect at the chromosome level 12--24 h postinfection. A
Publikováno v:
Journal of Cell Science. 78:97-103
We studied the mutagenic and carcinogenic effects on mammalian cells of two EcoRI DNA fragments of bovine adenovirus type3 (BAV-3) integrated into the pBR325 plasmid. Fragment D located between 3.6 and 19.7 map units, contains the viral oncogene, fra
Publikováno v:
Mutation research. 70(3)
The induction of chromosomal abberations and gene mutations was studied in Chinese hamster cells after separate and combined treatment with BUdR and SV40. Separate treatment of cells with BUdR or virus infection increased the yield of chromosomal abe
Publikováno v:
Moleculargeneral genetics : MGG. 187(3)
The mutagenic activity of the tsA239 mutant of SV40 which synthetizes a defective T antigen at 40 degrees C was investigated in Chinese hamster cells under permissive and nonpermissive temperature. At 33 degrees C the virus increased the yield of 6-m
Publikováno v:
Cancer genetics and cytogenetics. 13(2)
It was discovered in the 1970s that oncogenic viruses could induce gene mutations in mammalian cells. The phenomenon seems to be widespread: it was observed with all groups of DNA-containing viruses and some retroviruses. The mutagenic effects of the
Publikováno v:
Cancer genetics and cytogenetics. 37(1)
By using a selection procedure that excluded the transforming effect of SV40, reversions to several properties of normal phenotype were for the first time obtained in a transformed Chinese hamster cell line after SV40 infection. The value of inductio
Akademický článek
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