Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Varsha Bhatt-Mehta"'
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
The regulatory framework for considering the fetal effects of new drugs is limited. This is partially due to the fact that pediatric regulations (21 CFR subpart D) do not apply to the fetus, and only US Health and Human Service (HHS) regulations appl
Externí odkaz:
https://doaj.org/article/a64124a612a143cabac0ab7f15975980
Autor:
Varsha Bhatt-Mehta, Robert B. MacArthur, Raimar Löbenberg, Jeffrey J. Cies, Ibolja Cernak, Richard H. Parrish
Publikováno v:
AAPS Open, Vol 2, Iss 1, Pp 1-8 (2016)
Abstract The gap in the commercially-available pediatric drug products and formulations suitable for children, especially those below the age of 6 years, is long recognized. A group of clinicians and scientists with a common interest in pediatric dru
Externí odkaz:
https://doaj.org/article/bbd598645334498ba8437383c75a3356
Autor:
Varsha Bhatt-Mehta, Robert B. MacArthur, Raimar Löbenberg, Jeffrey J. Cies, Ibolja Cernak, Richard H. Parrish II
Publikováno v:
Pharmacy, Vol 3, Iss 4, Pp 284-294 (2015)
The lack of commercially-available pediatric drug products and dosage forms is well-known. A group of clinicians and scientists with a common interest in pediatric drug development and medicines-use systems developed a practical framework for identif
Externí odkaz:
https://doaj.org/article/c8af00a48bc84f5591c448ac74837482
Publikováno v:
The Journal of Clinical Pharmacology. 62
Clinical pharmacology is a branch of the field of pharmacology that evolved following the recognition that the nature, duration, and intensity of drug action depend on both the intrinsic properties of the drug and an interaction with the host to whom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103c368d0dbb25236925ee5993dcab0a
https://doi.org/10.1002/jcph.2102
https://doi.org/10.1002/jcph.2102
Publikováno v:
Journal of Experimental Pharmacology
Bronchopulmonary Dysplasia is the most common long-term respiratory morbidity of preterm infants, with the risk of development proportional to the degree of prematurity. While its pathophysiologic and histologic features have changed over time as neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6270c6f6ba8d6933c88fe45ab4f75f37
https://doi.org/10.2147/jep.s262350
https://doi.org/10.2147/jep.s262350
Autor:
Michael Cohen-Wolkowiez, William J. Muller, John S. Bradley, Amira Al-Uzri, Laura P. James, Kevin J. Downes, Anil R. Maharaj, Christoph P. Hornik, Huali Wu, Varsha Bhatt-Mehta, Antonio Arrieta
Publikováno v:
J Pharmacokinet Pharmacodyn
Currently employed methods for qualifying population physiologically-based pharmacokinetic (Pop-PBPK) model predictions of continuous outcomes (e.g., concentration-time data) fail to account for within-subject correlations and the presence of residua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befedb9d7230394efaccfa2aa8e8a5f5
https://doi.org/10.1007/s10928-020-09684-2
https://doi.org/10.1007/s10928-020-09684-2
Publikováno v:
Journal of Addiction Medicine. 13:227-234
Objective The objective of this study was to compare short-term outcomes of neonatal opioid withdrawal syndrome (NOWS) treatment in infants exposed in-utero to opioids and selective serotonin reuptake inhibitors (SSRIs) or opioids alone. Methods This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df30b7e427745e4be576926abb7bf8d
https://doi.org/10.1097/adm.0000000000000484
https://doi.org/10.1097/adm.0000000000000484
Publikováno v:
Hospital pediatrics. 10(11)
OBJECTIVES: Errors are common when preparing epinephrine for neonatal resuscitation. Epinephrine is available in two concentrations (1 mg/mL and 1 mg/10 mL) and requires weight-based calculations, which increases the risk of dosing errors. We develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62568b5ec480bf648d9d72d450a417c6
https://pubmed.ncbi.nlm.nih.gov/33087406
https://pubmed.ncbi.nlm.nih.gov/33087406
Autor:
Ebru Ergenekon, Simin K. Baygani, Janis M. Dionne, Varsha Bhatt-Mehta, Dina Apele-Freimane, Luana Pesco Koplowitz, Heike Rabe, Stephen Bremner, Hiroko Iwami, Martin Kluckow, Mark A. Turner, Eugene M. Dempsey, Agnes Klein, Beau Batton
Objectives: To determine the recommended blood pressure (BP) measurement methods in neonates after systematically analyzing the international literature regarding proper BP cuff size and measurement location and method.\ud Study Design: A literature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6828f07bec6a99bc92ccc854adb6fbab
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 152
Age-appropriate pediatric formulations for oral administration can be challenging to formulate. Development of such formulations is often time consuming, labor-intensive and costly. The Biopharmaceutical Classification System (BCS), developed more th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982efc211eb2fe7f9611d1aa27b32e2d
https://pubmed.ncbi.nlm.nih.gov/34315654
https://pubmed.ncbi.nlm.nih.gov/34315654