Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL.

Autor: Michael J Ricciardi, Diogo M Magnani, Alba Grifoni, Young-Chan Kwon, Martin J Gutman, Nathan D Grubaugh, Karthik Gangavarapu, Mark Sharkey, Cassia G T Silveira, Varian K Bailey, Núria Pedreño-Lopez, Lucas Gonzalez-Nieto, Helen S Maxwell, Aline Domingues, Mauricio A Martins, John Pham, Daniela Weiskopf, John Altman, Esper G Kallas, Kristian G Andersen, Mario Stevenson, Paola Lichtenberger, Hyeryun Choe, Stephen S Whitehead, Alessandro Sette, David I Watkins

Publikováno v: PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006000 (2017)

Zika virus (ZIKV) is a mosquito-borne flavivirus of significant public health concern. In the summer of 2016, ZIKV was first detected in the contiguous United States. Here we present one of the first cases of a locally acquired ZIKV infection in a de

Externí odkaz: https://doaj.org/article/e517563d855b415c83c79c2d54bdefb8

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

Autor: Jeffrey D. Lifson, Eva G. Rakasz, Brandon C. Rosen, Khoa Le, Mauricio A. Martins, Lucas Gonzalez-Nieto, Raiees Andrabi, Michael J. Ricciardi, Nicholas Pomplun, Martin J. Gutman, José M. Martinez-Navio, Sebastian P. Fuchs, Varian K. Bailey, Christine M. Dang, David I. Watkins, Kim L. Weisgrau, Ge Song, Diogo M. Magnani, Matthias Pauthner, Jens Wrammert, Dennis R. Burton, Nuria Pedreño-Lopez

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 16, Iss, Pp 225-237 (2020)
Molecular Therapy. Methods & Clinical Development

Structural characterization of the HIV-1 Envelope (Env) glycoprotein has facilitated the development of Env probes to isolate HIV-specific monoclonal antibodies (mAbs). However, preclinical studies have largely evaluated these virus-specific mAbs aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f617dce13c1a61ed593cb959456584c
https://doi.org/10.1016/j.omtm.2020.01.010

The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08 + Rhesus Macaques

Autor: Christopher L. Parks, David I. Watkins, David B. Allison, Eva G. Rakasz, Varian K. Bailey, Saverio Capuano, Mauricio A. Martins, Helen S. Maxwell, Jeffrey D. Lifson, Nuria Pedreño-Lopez, Lucas Gonzalez-Nieto, John D. Altman, Keisuke Ejima, Michael J. Ricciardi, Martin J. Gutman, Young C. Shin, Aline Domingues, Diogo M. Magnani, Ronald C. Desrosiers

Publikováno v: Journal of Virology. 93

Approximately 50% of rhesus macaques (RMs) expressing the major histocompatibility complex class I (MHC-I) allele Mamu-B*08 spontaneously control chronic-phase viremia after infection with the pathogenic simian immunodeficiency virus mac239 (SIVmac23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::755b0a6193ec7f0355192dc88030ea04
https://doi.org/10.1128/jvi.01626-18

Mamu-B*17 + Rhesus Macaques Vaccinated with env , vif , and nef Manifest Early Control of SIVmac239 Replication

Autor: Saverio Capuano, Mauricio A. Martins, Aline Domingues, Martin J. Gutman, Varian K. Bailey, Ronald C. Desrosiers, Maoli Yuan, Dennis R. Burton, Christopher L. Parks, David B. Allison, Keisuke Ejima, Jeffrey D. Lifson, John D. Altman, Diogo M. Magnani, Benjamin von Bredow, Eva G. Rakasz, Matthias Pauthner, Helen S. Maxwell, Damien C. Tully, Young C. Shin, Todd M. Allen, David J. Bean, David I. Watkins, Noemia S. Lima, Myrna C. Bonaldo, Nuria Pedreño-Lopez, Lucas Gonzalez-Nieto, Michael J. Ricciardi, David T. Evans

Publikováno v: Journal of Virology. 92

Certain major histocompatibility complex class I (MHC-I) alleles are associated with spontaneous control of viral replication in human immunodeficiency virus (HIV)-infected people and simian immunodeficiency virus (SIV)-infected rhesus macaques (RMs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0fc235616632dc69abb6174d0c78d0
https://doi.org/10.1128/jvi.00690-18

Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques

Autor: Dennis R. Burton, Margaret H. Gilbert, Tereance A. Myers, Robert V Blair, Pyone P. Aye, Martin J. Gutman, Michael J. Ricciardi, Faith Schiro, Kristian G. Andersen, Nathan Beutler, Stephen S. Whitehead, Pascal J. Goldschmidt-Clermont, Jaclyn Kwal, Diogo M. Magnani, Andrew A. Lackner, Mauricio A. Martins, Myrna C. Bonaldo, Rudolf P. Bohm, Christine L. Curry, Nathan D. Grubaugh, Justin G. Julander, Varian K. Bailey, Amitinder Kaur, Antonito T. Panganiban, Lucas Gonzalez-Nieto, Thomas F. Rogers, David I. Watkins, Nicholas J. Maness, Kathrine P. Falkenstein, Ronald C. Desrosiers, Nuria Pedreño-Lopez, Esper G. Kallas

Publikováno v: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Animal, Dairy, and Veterinary Science Faculty Publications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a minimally passaged ZIKV isolate from Rio de Janeiro, where a high rate of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bd323663489ea4d7980a22bb225481
https://pubmed.ncbi.nlm.nih.gov/29691387