C4b Binding Protein (C4BP) acts as an innate immune effector against Influenza A Virus

Autor: Varghese, PM, Murugaiah, V, Nazar, B, Temperton, N, Khan, HA, Alrokayan, S, Al-Ahdal, MN, Nal, B, A-Mohanna, F, Sim, RB, Kishore, U

International Scientific Partnership Programme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::609420291a82d83b62dc2493a9c63770
http://bura.brunel.ac.uk/handle/2438/21859

Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein.

Autor: Beirag N; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK., Varghese PM; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK.; School of Biosciences and Technology, Vellore Institute of Technology, Vellore 632014, India., Neto MM; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich, Kent ME4 4TB, UK., Al Aiyan A; Department of Veterinary Medicine, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates., Khan HA; Department of Biochemistry, College of Science, King Saud University, Riyadh 4545, Saudi Arabia., Qablan M; Department of Veterinary Medicine, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates., Shamji MH; Immunomodulation and Tolerance Group, Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London SW7 2BX, UK., Sim RB; MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich, Kent ME4 4TB, UK., Kishore U; Department of Veterinary Medicine, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.

Publikováno v: Viruses [Viruses] 2023 May 29; Vol. 15 (6). Date of Electronic Publication: 2023 May 29.

Human surfactant protein D facilitates SARS-CoV-2 pseudotype binding and entry in DC-SIGN expressing cells, and downregulates spike protein induced inflammation.

Autor: Beirag N; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Kumar C; Biomedical Informatics Centre, National Institute for Research in Reproductive and Child Health, ICMR, Mumbai, Maharashtra, India., Madan T; Department of Innate Immunity, National Institute for Research in Reproductive and Child Health, ICMR, Mumbai, India., Shamji MH; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute and NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom., Bulla R; Department of Life Sciences, University of Trieste, Trieste, Italy., Mitchell D; WMS - Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom., Murugaiah V; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Neto MM; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich, United Kingdom., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich, United Kingdom., Idicula-Thomas S; Biomedical Informatics Centre, National Institute for Research in Reproductive and Child Health, ICMR, Mumbai, Maharashtra, India., Varghese PM; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.; School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India., Kishore U; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.; Department of Veterinary Medicine, U.A.E. University, Al Ain, United Arab Emirates.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Jul 28; Vol. 13, pp. 960733. Date of Electronic Publication: 2022 Jul 28 (Print Publication: 2022).

Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection.

Autor: Varghese PM; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.; School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India., Mukherjee S; Biomedical Informatics Centre, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India., Al-Mohanna FA; Department of Cell Biology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Saleh SM; Department of Cell Biology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Almajhdi FN; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia., Beirag N; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Alkahtani SH; Department of Zoology, College of Sciences, King Saud University, Riyadh, Saudi Arabia., Rajkumari R; School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India., Nal Rogier B; INSERM U1104 Centre d'immunologie de Marseille-Luminy (CIML), Marseille, France., Sim RB; Department of Biochemistry, University of Oxford, Oxford, United Kingdom., Idicula-Thomas S; Biomedical Informatics Centre, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India., Madan T; Department of Innate Immunity, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India., Murugaiah V; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Kishore U; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Dec 09; Vol. 12, pp. 747654. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).

Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses.

Autor: Murugaiah V; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK., Varghese PM; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK., Beirag N; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK., De Cordova S; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK., Sim RB; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK., Kishore U; Biosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK.

Publikováno v: Viruses [Viruses] 2021 May 02; Vol. 13 (5). Date of Electronic Publication: 2021 May 02.