Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease

Autor: Passmore, Peter, Craig, David, Johnston, Janet, McGuinness, Bernadette, Todd, Stephen, Heun, Reinhard, Kölsch, Heike, Kehoe, Patrick G., Vardy, Emma R.L.C., Hooper, Nigel M., Pickering-Brown, Stuart, Snowden, Julie, Richardson, Anna, Jones, Matthew, Neary, David, Harris, Jennifer, Lowe, James, Smith, A. David, Wilcock, Gordon, Warden, Donald, Holmes, Clive, Chaudhury, Sultan, Patel, Tulsi, Barber, Imelda S., Guetta-Baranes, Tamar, Brookes, Keeley J., Chappell, Sally, Turton, James, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Hardy, John, Mann, David, Morgan, Kevin

Publikováno v: In Neurobiology of Aging February 2018 62:244-244

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

Autor: Passmore, Peter, Craig, David, Johnston, Janet, McGuinness, Bernadette, Todd, Stephen, Heun, Reinhard, Kölsch, Heike, Kehoe, Patrick G., Vardy, Emma R.L.C., Hooper, Nigel M., Mann, David M., Pickering-Brown, Stuart, Brown, Kristelle, Lowe, James, Morgan, Kevin, Smith, A. David, Wilcock, Gordon, Warden, Donald, Holmes, Clive, Sassi, Celeste, Nalls, Michael A., Ridge, Perry G., Gibbs, Jesse R., Ding, Jinhui, Lupton, Michelle K., Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S., Medway, Christopher, Clement, Naomi, Lord, Jenny, Turton, James, Bras, Jose, Almeida, Maria R., Holstege, Henne, Louwersheimer, Eva, van der Flier, Wiesje M., Scheltens, Philip, Van Swieten, John C., Santana, Isabel, Oliveira, Catarina, Powell, John F., Kauwe, John S., Cruchaga, Carlos, Goate, Alison M., Singleton, Andrew B., Guerreiro, Rita, Hardy, John

Publikováno v: In Neurobiology of Aging October 2016 46:235-235

Proteolytic mechanisms in amyloid-β metabolism: therapeutic implications for Alzheimer's disease

Autor: Vardy, Emma R.L.C., Catto, Andrew J., Hooper, Nigel M.

Publikováno v: In Trends in Molecular Medicine 2005 11(10):464-472

ABCA7 p.G215S as potential protective factor for Alzheimer’s disease

Autor: Sassi, C., Nalls, M.A., Ridge, P.G., Gibbs, R., Ding, J., Lupton, M.K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K.S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M.R., Passmore, Peter, Craig, David, Johnston, Janet, McGuinness, Bernadette, Todd, Stephen, Heun, Reinhard, Kölsch, Heike, Kehoe, Patrick G., Vardy, Emma R.L.C., Hooper, Nigel M., Mann, David M., Pickering-Brown, Stuart, Brown, Kristelle, Lowe, James, Morgan, Kevin, Smith, A. David, Wilcock, Gordon, Warden, Donald, Holmes, Clive, Holstege, H., Louwersheimer, E., van der Flier, W., Scheltens, P., Van Swieten, J.C., Santana, I., Oliveira, C., Morgan, K., Powell, J.F., Kauwe, J.S., Cruchaga, C., Goate, A.M., Singleton, A.B., Guerreiro, R., Hardy, J.

Publikováno v: Sassi, C, Nalls, M A, Ridge, P G, Gibbs, R, Ding, J, Lupton, M K, Troakes, C, Lunnon, K, Al-Sarraj, S, Brown, K S, Medway, C, Clement, N, Lord, J, Turton, J, Bras, J, Almeida, M R, Passmore, P, Craig, D, Johnston, J, McGuinness, B, Todd, S, Heun, R, Kölsch, H, Kehoe, P G, Vardy, E R L C, Hooper, N M, Mann, D M, Pickering-Brown, S, Brown, K, Lowe, J, Morgan, K, Smith, A D, Wilcock, G, Warden, D, Holmes, C, Holstege, H, Louwersheimer, E, van der Flier, W, Scheltens, P, Van Swieten, J C, Santana, I, Oliveira, C, Morgan, K, Powell, J F, Kauwe, J S, Cruchaga, C, Goate, A M, Singleton, A B, Guerreiro, R & Hardy, J 2016, ' ABCA7 p.G215S as potential protective factor for Alzheimer’s disease ', Neurobiology of Aging . https://doi.org/10.1016/j.neurobiolaging.2016.04.004

Genome-wide association studies (GWASs) have been effective approaches to dissect common genetic variability underlying complex diseases in a systematic and unbiased way. Recently, GWASs have led to the discovery of over 20 susceptibility loci for Al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::eb4584109fc16a8d275f76dadf810b63
https://kclpure.kcl.ac.uk/en/publications/6f698269-c05c-4eb9-b78b-8ef4e2c06634

Alkaline Phosphatase Is Increased in both Brain and Plasma in Alzheimer's Disease.

Autor: Vardy, Emma R.L.C., Kellett, Katherine A.B., Cocklin, Sarah L., Hooper, Nigel M.

Publikováno v: Neurodegenerative Diseases; 2011, Vol. 9 Issue 1, p31-37, 7p, 2 Charts, 2 Graphs