Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vardhman, Rakyan"'
Autor:
Amy P. Webster, Simone Ecker, Ismail Moghul, Xiaohong Liu, Pawan Dhami, Sarah Marzi, Dirk S. Paul, Michelle Kuxhausen, Stephanie J. Lee, Stephen R. Spellman, Tao Wang, Andrew Feber, Vardhman Rakyan, Karl S. Peggs, Stephan Beck
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Allogeneic hematopoietic cell transplantation (HCT) is used to treat many blood-based disorders and malignancies, however it can also result in serious adverse events, such as the development of acute graft-versus-host disease (aGVHD). This study aim
Externí odkaz:
https://doaj.org/article/951e2cf5b5514896b6ba6afd2a1f92db
Autor:
B. William Ogunkolade, Antonysunil Adaikalakoteswari, Shirleny Romualdo Cardoso, Rob Lowe, Nisha Patel, Vardhman Rakyan, Sarah Finer, Martin Wabitsch, Ponnusamy Saravanan, Gyanendra Tripathi, Elena Bochukova, Graham A Hitman
Publikováno v:
Epigenetics, Vol 17, Iss 10, Pp 1219-1233 (2022)
Vitamin B12 has multiple biochemical functions including in the one-carbon cycle generating a methyl group for DNA methylation, and metabolism of fatty acids and amino acids to generate energy via the citric acid cycle. The aim of our study was to us
Externí odkaz:
https://doaj.org/article/da875f7227f04099ad63049ddd7f3934
Autor:
Ricardo Costeira, Joseph Aduse-Opoku, Jon J. Vernon, Francisco Rodriguez-Algarra, Susan Joseph, Deirdre A. Devine, Philip D. Marsh, Vardhman Rakyan, Michael A. Curtis, Jordana T. Bell
Publikováno v:
mSystems, Vol 8, Iss 4 (2023)
ABSTRACT Periodontal disease is a chronic inflammatory disease in which the oral pathogen Porphyromonas gingivalis plays an important role. Porphyromonas gingivalis expresses virulence determinants in response to higher hemin concentrations, but the
Externí odkaz:
https://doaj.org/article/c5854e0bd0ed43ff85b241856c52a9f6
Autor:
Claire Vinel, Gabriel Rosser, Loredana Guglielmi, Myrianni Constantinou, Nicola Pomella, Xinyu Zhang, James R. Boot, Tania A. Jones, Thomas O. Millner, Anaelle A. Dumas, Vardhman Rakyan, Jeremy Rees, Jamie L. Thompson, Juho Vuononvirta, Suchita Nadkarni, Tedani El Assan, Natasha Aley, Yung-Yao Lin, Pentao Liu, Sven Nelander, Denise Sheer, Catherine L. R. Merry, Federica Marelli-Berg, Sebastian Brandner, Silvia Marino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The identification of patient-specific disease mechanisms and druggable targets is crucial for precision medicine in glioblastoma. Here, the authors show that comparing patients-matched glioma-initiating cells with neural stem cells enables the disco
Externí odkaz:
https://doaj.org/article/eef727b592d24a7697303fa96e18e608
Autor:
Amy P. Webster, Simone Ecker, Ismail Moghul, Pawan Dhami, Sarah Marzi, Dirk S. Paul, Michelle Kuxhausen, Stephanie J. Lee, Stephen R. Spellman, Tao Wang, Andrew Feber, Vardhman Rakyan, Karl S. Peggs, Stephan Beck
Allogeneic hematopoietic cell transplantation (HCT) is used to treat many blood-based disorders and malignancies. While this is an effective treatment, it can result in serious adverse events, such as the development of acute graft-versus-host diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0de4d76893b4b715cbb9355fbf563fe
https://doi.org/10.1101/2022.03.08.22272071
https://doi.org/10.1101/2022.03.08.22272071
Autor:
Lowe, Robert, Barton, Carl, Jenkins, Christopher, Ernst, Christina, Forman, Oliver, Fernandez-Twinn, Denise, Bock, Christoph, Rossiter, Stephen, Faulkes, Chris, Ozanne, Susan, Walter, Lutz, Odom, Duncan, Mellersh, Cathryn, Vardhman Rakyan
Barplot of the negative log gradient of age in weeks against methylation for multiple different tissues from human samples. (DOCX 113 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5734c04d811169cd1929d08492a894d1
Table S1. Compositions of the control (CT) diet and the protein restricted (PR) diet. Table S2. List of all male mice studied with each litter represented by the first two numbers and letter of each ID. Table S3. Sequences of primers used for targete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8e5327a3d57072cb995cf736d3f8a2
Autor:
Yang, Zhen, Wong, Andrew, Kuh, Diana, Paul, Dirk, Vardhman Rakyan, R. Leslie, Shijie Zheng, Widschwendter, Martin, Beck, Stephan, Teschendorff, Andrew
Supplementary information document with all supplementary figures and their legends. (PDF 1902Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29aec3ad38bd66c4ffd4f1903f6e5216
Autor:
Paul, Dirk, Jones, Allison, Sellar, Rob, Neema Mayor, Feber, Andrew, Webster, Amy, Neuza Afonso, Ruhena Sergeant, Szydlo, Richard, Apperley, Jane, Widschwendter, Martin, Mackinnon, Stephen, Marsh, Steven, J. Madrigal, Vardhman Rakyan, Peggs, Karl, Beck, Stephan
Annotation of top-ranked DMPs using epigenomic reference datasets. The genomic locus on chromosome 14q24.2 (position = 70,261,006–70,349,114; genome build = hg19) harboring the top-ranked DMR is shown using the WashU Epigenome Browser v40.0.0 ( htt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4f7bc830b371f60f40597c0c86cb3b
Autor:
Paul, Dirk, Jones, Allison, Sellar, Rob, Neema Mayor, Feber, Andrew, Webster, Amy, Neuza Afonso, Ruhena Sergeant, Szydlo, Richard, Apperley, Jane, Widschwendter, Martin, Mackinnon, Stephen, Marsh, Steven, J. Madrigal, Vardhman Rakyan, Peggs, Karl, Beck, Stephan
Ontology annotation of genes flanking DMRs using GREAT. We report the ontology of genes flanking the 453 identified DMRs. Specifically, we indicate all enriched terms in the binomial test over genomic regions at an FDR of less than 5Â %. (PDF 107 kb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b346499da9cb32b8810a0797c2a8b3