The extracellular ATP receptor P2RX7 imprints a pro-memory transcriptional signature in effector CD8+T cells

Autor: Stephen C. Jameson, van Dijk S, Wanhainen Km, Borges da Silva H, Changwei Peng, Vardam-Kaur T

Development of central memory (Tcm) and resident memory (Trm) CD8+T cells, which respectively promote immunity in the circulation and in barrier tissues, is not completely understood. Tcm and Trm cells may arise from common precursors, however their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d50e45def4eeda3f12de943980af732
https://doi.org/10.1101/2021.05.25.445679

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The ATP-exporting channel Pannexin-1 promotes CD8 ⁺ T cell effector and memory responses.

Autor: Vardam-Kaur T; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.; Current address: Omeros Corporation, Seattle, Washington, United States., Banuelos A; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Gabaldon-Parish M; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.; Current address: University of New Mexico, Albuquerque, New Mexico, United States., Macedo BG; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Salgado CL; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Wanhainen KM; Center for Immunology, University of Minnesota, Minneapolis, Minnesota, United States., Zhou MH; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., van Dijk S; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.; Current address: Biomedical Sciences Graduate Program, University of California, San Diego, California, United States., Santiago-Carvalho I; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Beniwal AS; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.; Department of Cancer Biology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Leff CL; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Peng C; Center for Immunology, University of Minnesota, Minneapolis, Minnesota, United States.; Current address: Department of Immunology & HMS Center for Immune Imaging, Harvard Medical School, Boston, Massachusetts, United States., Tran NL; Department of Cancer Biology, Mayo Clinic Arizona, Scottsdale, Arizona, United States., Jameson SC; Center for Immunology, University of Minnesota, Minneapolis, Minnesota, United States., da Silva HB; Department of Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.; Department of Cancer Biology, Mayo Clinic Arizona, Scottsdale, Arizona, United States.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 02. Date of Electronic Publication: 2024 May 02.