Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Varda Gross-Tsur"'
Autor:
Harry J. Hirsch, Varda Gross-Tsur
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-5 (2021)
Abstract Growth hormone treatment for children with Prader Willi syndrome (PWS) has shown proven benefits not only in increasing final height but also with positive effects on body composition and motor development. In a recent letter to the editor,
Externí odkaz:
https://doaj.org/article/09f6c5299e324223a3c45224ed5dce15
Autor:
Ibrahim Knani, Brian J. Earley, Shiran Udi, Alina Nemirovski, Rivka Hadar, Asaad Gammal, Resat Cinar, Harry J. Hirsch, Yehuda Pollak, Itai Gross, Talia Eldar-Geva, Daniela P. Reyes-Capo, Joan C. Han, Andrea M. Haqq, Varda Gross-Tsur, Rachel Wevrick, Joseph Tam
Publikováno v:
Molecular Metabolism, Vol 5, Iss 12, Pp 1187-1199 (2016)
Objective: Extreme obesity is a core phenotypic feature of Prader–Willi syndrome (PWS). Among numerous metabolic regulators, the endocannabinoid (eCB) system is critically involved in controlling feeding, body weight, and energy metabolism, and a g
Externí odkaz:
https://doaj.org/article/0514992d71c34dd994565af16272ceea
Autor:
Hamutal Avrahamy, Yehuda Pollak, Liron Shriki-Tal, Larry Genstil, Harry J. Hirsch, Varda Gross-Tsur, Fortu Benarroch
Publikováno v:
Comprehensive Psychiatry, Vol 58, Iss , Pp 189-197 (2015)
Objective: Prader–Willi syndrome (PWS) is a genetic multisystem disorder with various medical, cognitive, behavioral and psychiatric problems. PWS is caused by the lack of expression of paternal genes on chromosome 15q2-q13 due to a deletion (70–
Externí odkaz:
https://doaj.org/article/292f3bf5daa3490596984cac33366f8a
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136864 (2015)
Hyperphagia, low resting energy expenditure, and abnormal body composition contribute to severe obesity in Prader Willi syndrome (PWS). Irisin, a circulating myokine, stimulates "browning" of white adipose tissue resulting in increased energy expendi
Externí odkaz:
https://doaj.org/article/3d5772be10654461a8eb87000a26281c
Autor:
Lea K Davis, Dongmei Yu, Clare L Keenan, Eric R Gamazon, Anuar I Konkashbaev, Eske M Derks, Benjamin M Neale, Jian Yang, S Hong Lee, Patrick Evans, Cathy L Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrio, Oscar J Bienvenu, Michael H Bloch, Rianne M Blom, Ruth D Bruun, Cathy L Budman, Beatriz Camarena, Desmond Campbell, Carolina Cappi, Julio C Cardona Silgado, Danielle C Cath, Maria C Cavallini, Denise A Chavira, Sylvain Chouinard, David V Conti, Edwin H Cook, Vladimir Coric, Bernadette A Cullen, Dieter Deforce, Richard Delorme, Yves Dion, Christopher K Edlund, Karin Egberts, Peter Falkai, Thomas V Fernandez, Patience J Gallagher, Helena Garrido, Daniel Geller, Simon L Girard, Hans J Grabe, Marco A Grados, Benjamin D Greenberg, Varda Gross-Tsur, Stephen Haddad, Gary A Heiman, Sian M J Hemmings, Ana G Hounie, Cornelia Illmann, Joseph Jankovic, Michael A Jenike, James L Kennedy, Robert A King, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L Lowe, Fabio Macciardi, James T McCracken, Lauren M McGrath, Sandra C Mesa Restrepo, Rainald Moessner, Jubel Morgan, Heike Muller, Dennis L Murphy, Allan L Naarden, William Cornejo Ochoa, Roel A Ophoff, Lisa Osiecki, Andrew J Pakstis, Michele T Pato, Carlos N Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L Rauch, Tobias J Renner, Victor I Reus, Margaret A Richter, Mark A Riddle, Mary M Robertson, Roxana Romero, Maria C Rosàrio, David Rosenberg, Guy A Rouleau, Stephan Ruhrmann, Andres Ruiz-Linares, Aline S Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S Singer, Jan H Smit, Dan J Stein, E Strengman, Jay A Tischfield, Ana V Valencia Duarte, Homero Vallada, Filip Van Nieuwerburgh, Jeremy Veenstra-Vanderweele, Susanne Walitza, Ying Wang, Jens R Wendland, Herman G M Westenberg, Yin Yao Shugart, Euripedes C Miguel, William McMahon, Michael Wagner, Humberto Nicolini, Danielle Posthuma, Gregory L Hanna, Peter Heutink, Damiaan Denys, Paul D Arnold, Ben A Oostra, Gerald Nestadt, Nelson B Freimer, David L Pauls, Naomi R Wray, S Evelyn Stewart, Carol A Mathews, James A Knowles, Nancy J Cox, Jeremiah M Scharf
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003864 (2013)
The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated variants. We have quanti
Externí odkaz:
https://doaj.org/article/dcefb124869a49fdb60299acf97e56f6
Autor:
Amanda E. Marker, David F. Short, Talia Eldar-Geva, Harry J. Hirsch, Varda Gross-Tsur, Maayan Tiomkin, Ari Zimran, Thomas N. Hangartner
Publikováno v:
Journal of Orthopaedic Translation, Vol 2, Iss 4, Pp 236-237 (2014)
Externí odkaz:
https://doaj.org/article/21ebe54ec0ed4d619f39a95831a85f9b
Autor:
Varda Gross-Tsur, Harry J. Hirsch
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-5 (2021)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Growth hormone treatment for children with Prader Willi syndrome (PWS) has shown proven benefits not only in increasing final height but also with positive effects on body composition and motor development. In a recent letter to the editor, Hoybye an
Autor:
Alla Kuzminsky, Liora Sagi, Adi Aran, Luba Blumkin, Tehila Klopstock, Dorit Lev, Dafna Guttman, Lilach Shemer Meiri, Reeval Segel, Suleyman Gulsuner, Michal Yechieli, Mary Claire King, Varda Gross-Tsur, Aviva Fattal, Paul Renbaum, Hilla Ben-Pazi, Ephrat Lahad Levy, Sharon Zeligson, Nira Schneebaum Sender, Dorit Shmueli, Thomas J. Walsh, Amnon Lahad
Publikováno v:
Journal of Medical Genetics. 59:759-767
ObjectiveTo determine the yield of genetic diagnoses using chromosomal microarray (CMA) and trio whole exome sequencing (WES), separately and combined, among patients with cryptogenic cerebral palsy (CP).MethodsTrio WES of patients with prior CMA ana
Autor:
Dvorit Derei, Larry Genstil, Varda Gross-Tsur, Harry J. Hirsch, Anna Shay, Fortu Benarroch, Naama Srebnik-Moshe
Publikováno v:
Archives of Sexual Behavior. 50:2259-2266
Many genetic disorders associated with intellectual disability are characterized by unique behavioral phenotypes which may have serious psychological consequences such as increasing the risk for sexual abuse (SA). Prader–Willi Syndrome (PWS), a sev
Autor:
Abdalla Salama, Hen Y. Sela, Noa Gross Even-Zohar, Varda Gross-Tsur, Talia Eldar-Geva, Harry J. Hirsch, Naama Srebnik
Publikováno v:
Prenatal Diagnosis. 40:878-884
OBJECTIVES Prader-Willi syndrome (PWS) is a neurogenetic disorder characterized by mental retardation, morbid obesity, and endocrine and behavior disorders. We previously showed in a small group of patients that PWS may have a unique prenatal phenoty