Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers.

Autor: Eichholz K; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Fukazawa Y; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Peterson CW; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Department of Laboratory Medicine and., Haeseleer F; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Department of Laboratory Medicine and.; Department of Medicine, University of Washington, Seattle, Washington, USA., Medina M; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Hoffmeister S; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Duell DM; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Varco-Merth BD; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Dross S; Washington National Primate Research Center (WaNPRC), Seattle, Washington, USA.; Department of Microbiology, University of Washington, Seattle, Washington, USA., Park H; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Labriola CS; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Axthelm MK; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Murnane RD; Washington National Primate Research Center (WaNPRC), Seattle, Washington, USA., Smedley JV; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Jin L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Gong J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Rust BJ; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Center, Seattle, Washington, USA., Fuller DH; Washington National Primate Research Center (WaNPRC), Seattle, Washington, USA.; Department of Microbiology, University of Washington, Seattle, Washington, USA., Kiem HP; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA., Picker LJ; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Okoye AA; Vaccine and Gene Therapy Institute and Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, Beaverton, Oregon, USA., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Department of Laboratory Medicine and.; Department of Medicine, University of Washington, Seattle, Washington, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Apr 01; Vol. 134 (7). Date of Electronic Publication: 2024 Apr 01.

Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence.

Autor: Varco-Merth, Benjamin^1,2 (AUTHOR), Chaunzwa, Morgan^1,2 (AUTHOR), Duell, Derick M.^1,2 (AUTHOR), Marenco, Alejandra^1,2 (AUTHOR), Goodwin, William^1,2 (AUTHOR), Dannay, Rachel^1,2 (AUTHOR), Nekorchuk, Michael^1,2 (AUTHOR), Shao, Danica³ (AUTHOR), Busman-Sahay, Kathleen^1,2 (AUTHOR), Fennessey, Christine M.⁴ (AUTHOR), Silipino, Lorna⁴ (AUTHOR), Hull, Michael⁴ (AUTHOR), Bosche, William J.⁴ (AUTHOR), Fast, Randy⁴ (AUTHOR), Oswald, Kelli⁴ (AUTHOR), Shoemaker, Rebecca⁴ (AUTHOR), Bochart, Rachele² (AUTHOR), MacAllister, Rhonda² (AUTHOR), Labriola, Caralyn S.^1,2 (AUTHOR), Smedley, Jeremy V.^1,2 (AUTHOR)

Publikováno v: PLoS Pathogens. 8/22/2024, Vol. 20 Issue 8, p1-28. 28p.

Immunometabolites in viral infections: Action mechanism and function.

Autor: Bouzari B; Department of Pathology, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran., Chugaeva UY; Department of Pediatric, Preventive Dentistry and Orthodontics, Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Karampoor S; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran., Mirzaei R; Venom and Biotherapeutics Molecules Lab, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.

Publikováno v: Journal of medical virology [J Med Virol] 2024 Jul; Vol. 96 (7), pp. e29807.