Zobrazeno 1 - 10
of 949
pro vyhledávání: '"Varble A"'
Autor:
Jose F. Delgado, Joshua W. Owen, William F. Pritchard, Nicole A. Varble, Tania L. Lopez-Silva, Andrew S. Mikhail, Antonio Arrichiello, Trisha Ray, Robert Morhard, Tabea Borde, Laetitia Saccenti, Sheng Xu, Jocelyne Rivera, Joel P. Schneider, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Intratumoral injections have the potential for enhanced cancer treatment efficacy while reducing costs and systemic exposure. However, intratumoral drug injections can result in substantial off-target leakage and are invisible under standard
Externí odkaz:
https://doaj.org/article/2731478a74a94c528685239e866607f1
Autor:
J. Mülmenstädt, E. Gryspeerdt, S. Dipu, J. Quaas, A. S. Ackerman, A. M. Fridlind, F. Tornow, S. E. Bauer, A. Gettelman, Y. Ming, Y. Zheng, P.-L. Ma, H. Wang, K. Zhang, M. W. Christensen, A. C. Varble, L. R. Leung, X. Liu, D. Neubauer, D. G. Partridge, P. Stier, T. Takemura
Publikováno v:
Atmospheric Chemistry and Physics, Vol 24, Pp 7331-7345 (2024)
General circulation models' (GCMs) estimates of the liquid water path adjustment to anthropogenic aerosol emissions differ in sign from other lines of evidence. This reduces confidence in estimates of the effective radiative forcing of the climate by
Externí odkaz:
https://doaj.org/article/55bdcc9ea1de4f44826ec77776bf8ff1
Autor:
Jose F. Delgado, William F. Pritchard, Nicole Varble, Tania L. Lopez-Silva, Antonio Arrichiello, Andrew S. Mikhail, Robert Morhard, Trisha Ray, Michal M. Havakuk, Alex Nguyen, Tabea Borde, Joshua W. Owen, Joel P. Schneider, John W. Karanian, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Liver cancer ranks as the fifth leading cause of cancer-related death globally. Direct intratumoral injections of anti-cancer therapeutics may improve therapeutic efficacy and mitigate adverse effects compared to intravenous injections. Some
Externí odkaz:
https://doaj.org/article/68305af4433440b69466194e5cca2e34
Publikováno v:
Atmospheric Chemistry and Physics, Vol 24, Pp 6455-6476 (2024)
The Weather Research Forecasting (WRF) version 4.3 model is configured within a Lagrangian framework to quantify the impact of aerosols on evolving cloud fields. Kilometer-scale simulations utilizing meteorological boundary conditions are based on 10
Externí odkaz:
https://doaj.org/article/35a0a4b1cddc45d9a04bb1a7b0f705de
Publikováno v:
Atmospheric Chemistry and Physics, Vol 24, Pp 5287-5302 (2024)
Process-oriented observational constraints for the anthropogenic effective radiative forcing due to aerosol–cloud interactions (ERFaci) are highly desirable because the uncertainty associated with ERFaci poses a significant challenge to climate pre
Externí odkaz:
https://doaj.org/article/e7ece2caff3a4150945f4fb802c127a1
Autor:
Elisabet Bjånes, Alexandra Stream, Axel B. Janssen, Paddy S. Gibson, Afonso M. Bravo, Samira Dahesh, Jonathon L. Baker, Andrew Varble, Victor Nizet, Jan-Willem Veening
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT While genome-wide transposon mutagenesis screens have identified numerous essential genes in the significant human pathogen Streptococcus pyogenes (group A Streptococcus or GAS), many of their functions remain elusive. This knowledge gap is
Externí odkaz:
https://doaj.org/article/ed6fa4f1feeb435ca679c1fca0e2ee86
Autor:
S. Tang, A. C. Varble, J. D. Fast, K. Zhang, P. Wu, X. Dong, F. Mei, M. Pekour, J. C. Hardin, P.-L. Ma
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 6355-6376 (2023)
Poor representations of aerosols, clouds, and aerosol–cloud interactions (ACIs) in Earth system models (ESMs) have long been the largest uncertainties in predicting global climate change. Huge efforts have been made to improve the representation of
Externí odkaz:
https://doaj.org/article/bf55c6f152374f68a1f6376a5e04c8ac
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 13791-13808 (2023)
Deep convective updraft invigoration via indirect effects of increased aerosol number concentration on cloud microphysics is frequently cited as a driver of correlations between aerosol and deep convection properties. Here, we critically evaluate the
Externí odkaz:
https://doaj.org/article/ecd6ebe746a24ba6a02a4fd848b526d8
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 13523-13553 (2023)
The impact of aerosol number concentration on cloud albedo is a persistent source of spread in global climate predictions due to multi-scale, interactive atmospheric processes that remain difficult to quantify. We use 5 years of geostationary satelli
Externí odkaz:
https://doaj.org/article/f4010ff8451a4316a9f3ff35978f9281
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract A stochastic horizontal subgrid‐scale mixing scheme is evaluated in ensemble simulations of a tropical oceanic deep convection case using a horizontal grid spacing (Δh) of 3 km. The stochastic scheme, which perturbs the horizontal mixing
Externí odkaz:
https://doaj.org/article/c2f3ff61e2bc4ae09e50cd1692d92136