Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Varatharajan Sudhahar"'
Publikováno v:
Nutrition Research. 27:778-787
In the hypercholesterolemic condition, the net result of combined lipemic-oxidative and inflammatory aberrations is manifested as an increase in adhesion molecule expression, increased vascular permeability, and the progress of atherogenesis. The aim
Publikováno v:
Atherosclerosis. 189:115-122
The aim of the present study is to evaluate the effect of eicosapentaenoic acid (EPA), dl -α-lipoic acid (LA) and eicosapentaenoate-lipoate (EPA-LA) derivative on the atherogenic disturbances in hypercholesterolemic atherogenic animals. Eight groups
Autor:
Periyasamy Thandavan Sudharsan, Yenjerla Mythili, Palaninathan Varalakshmi, Varatharajan Sudhahar
Publikováno v:
Journal of Pharmacy and Pharmacology. 57:1437-1444
Cyclophosphamide, an alkylating agent widely used in cancer chemotherapy, causes fatal cardiotoxicity. In this study, lupeol, a pentacyclic triterpene isolated from Crataeva nurvala stem bark, and its ester, lupeol linoleate, were investigated for th
Publikováno v:
Clinica Chimica Acta. 355:197-204
Background Dietary cholesterol plays an important role in development of atherogenesis and cardiovascular disease. We explored the lipemic-oxidative injury in the hypercholesterolemic atherogenic animals. The effects of eicosapentaenoic acid (EPA), d
Publikováno v:
Journal of natural products. 71(9)
The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental hyperoxaluria. Hyperoxaluria was induced in male Wistar rats with 0.75% ethylene glyco
Publikováno v:
Molecular and cellular biochemistry. 317(1-2)
The association between hypercholesterolemia and kidney damage has been well known for last few decades. The oxidative stress and inflammatory responses are involved in renal injury, which is upregulated in hypercholesterolemic condition. The present
Publikováno v:
Molecular nutritionfood research. 50(12)
Cholesterol feeding has been often used to study the etiology of hypercholesterolaemia-related metabolic disturbances. The aim of the present study is to investigate the effects of a pentacyclic triterpene, lupeol, and its ester derivative on hepatic
Publikováno v:
Molecular and cellular biochemistry. 295(1-2)
In the present study, the role of pentacyclic triterpenes, lupeol and its ester lupeol linoleate, was studied in relation to hepatic oxidative abnormalities and lipoprotein peroxidation in hypercholesterolemic rats. Hypercholesterolemia was induced i
Autor:
Periyasamy Thandavan Sudharsan, Varatharajan Sudhahar, Yenjerla Mythili, Palaninathan Varalakshmi
Publikováno v:
European journal of pharmacology. 543(1-3)
Cyclophosphamide is a potent alkylating agent used in cancer chemotherapy and immunosuppression. The present study is aimed at evaluating the role of a potent antioxidant lipoic acid in cyclophosphamide induced hyperlipidemic cardiomyopathy. Adult ma
Publikováno v:
Prostaglandins, leukotrienes, and essential fatty acids. 75(1)
Hypercholesterolemia, an independent risk factor for increased oxidative renal injury, is associated with the formation of oxidized low-density lipoprotein. Production of reactive oxygen species and nitrogen species have been implicated in diet-induc