Výsledky vyhledávání - "Varadaraj Vasudevan"

Role of Haptoglobin 2-2 genotype on disease progression and mortality among South Indian Chronic Kidney Disease Patients

Autor: Varadaraj Vasudevan, Tharmarajan Ramprasath, Krishnaswamy Sampathkumar, Shanavas Syed Mohamed Puhari, Subramani Yuvaraj, Govindan Sadasivam selvam

Background Haptoglobin (HP), a plasma glycoprotein, binds to free hemoglobin and prevents the loss of iron and kidney damage. Polymorphism in the HP gene affects its enzyme activity, and different genotypes result in varied antioxidant, angiogenic an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c99269a683990d213a425c80cace1e3
https://doi.org/10.21203/rs.3.rs-2221770/v1

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Isolation and characterization of fucoidan from four brown algae and study of the cardioprotective effect of fucoidan from Sargassum wightii against high glucose‐induced oxidative stress in H9c2 cardiomyoblast cells

Autor: Shanavas Syed Mohamed Puhari, Subramani Yuvaraj, Varadaraj Vasudevan, Tharmarajan Ramprasath, Prabhakaran Rajkumar, Kulanthaiyesu Arunkumar, Chinnaiah Amutha, Govindan Sadasivam Selvam

Publikováno v: Journal of Food Biochemistry. 46

Oxidative stress plays a vital role in the initiation and progression of diabetic cardiomyopathy (DCM). Increased cardiac dysfunction and apoptosis in DCM are independent factors associated with hypertension or coronary artery disease. Fucoidan, a cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085dc7efba9566b4e565de509867c3cc
https://doi.org/10.1111/jfbc.14412

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Chrysin reduces hypercholesterolemia-mediated atherosclerosis through modulating oxidative stress, microflora, and apoptosis in experimental rats

Autor: Subramani Yuvaraj, Sundrasen Sasikumar, Shanavas Syed Mohamed Puhari, Tharmarajan Ramprasath, Nagarethinam Baskaran, Varadaraj Vasudevan, Govindan Sadasivam Selvam

Publikováno v: Journal of food biochemistryREFERENCES. 46(11)

Chrysin (Chy) is known for various biological proprieties such as inhibitory effects on inflammation, cancer, oxidative stress, aging, and atherosclerosis. However, the hypolipidemic activity of Chy and its mechanistic action remains unclear in cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ecfd1f77d93b4480655862290c4f47
https://pubmed.ncbi.nlm.nih.gov/35892244

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Chrysin attenuates high-fat-diet-induced myocardial oxidative stress via upregulating eNOS and Nrf2 target genes in rats

Autor: Govindan Sadasivam Selvam, Balakrishnan Saravanan, Varadaraj Vasudevan, Sundaresan Sasikumar, Subramani Yuvaraj, Tharmarajan Ramprasath

Publikováno v: Molecular and Cellular Biochemistry. 476:2719-2727

Hypercholesterolemia is one of the risk factors associated with increased morbidity and mortality in cardiovascular disorders. Chrysin (Chy) is reported to exhibit anti-inflammatory, anti-cancerous, anti-oxidative, anti-aging, and anti-atherogenic pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a59bdbf06708b0db311c4b96bacf32
https://doi.org/10.1007/s11010-021-04105-5

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HP 2-2 genotype Predicts Rapid Disease Progression in Nondialysis Patients and Mortality among South Indian ESRD Patients

Autor: Varadaraj Vasudevan, Tharmarajan Ramprasath, Krishnaswamy Sampathkumar, Shanavas Syed Mohamed Puhari, Subramani Yuvaraj, Govindan Sadasivam Selvam

Objectives Haptoglobin (HP), a plasma glycoprotein, binds to free hemoglobin and prevents the loss of iron and kidney damage. In a prospective study, we determined whether HP variants (HP 1–1, HP 2 − 1, HP 2–2) are associated with chronic kidne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1d2f7b76061173f40a6bab211b26f83
https://doi.org/10.21203/rs.3.rs-1591138/v1

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Chrysin protects cardiac H9c2 cells against H

Autor: Subramani, Yuvaraj, Arumugam Kalaiselvi, Ajeeth, Shanavas Syed Mohamed, Puhari, Albert, Abhishek, Tharmarajan, Ramprasath, Varadaraj, Vasudevan, Narasimman, Vignesh, Govindan Sadasivam, Selvam

Publikováno v: Molecular and cellular biochemistry.

Oxidative and endoplasmic reticulum (ER) stress-mediated cardiac apoptosis is an essential pathological process in cardiovascular diseases (CVDs). Chrysin (Chy) is a natural flavonoid that exerts several health benefits, particularly anti-oxidative a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8796da9683a0d5f05186b3a1f7db82cb
https://pubmed.ncbi.nlm.nih.gov/35943656

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GSTM1-null allele predicts rapid disease progression in nondialysis patients and mortality among South Indian ESRD patients

Autor: Krishnaswamy Sampathkumar, Varadaraj Vasudevan, Govindan Sadasivam Selvam, Tharmarajan Ramprasath, Subramani Yuvaraj, Shanavas Syed Mohamed Puhari

Publikováno v: Molecular and cellular biochemistry. 469(1-2)

Chronic kidney disease (CKD) is one of the main causes of early death in humans worldwide. Glutathione S-Transferases (GSTs) are involved in a series of xenobiotics metabolism and free radical scavenging. The previous studies elucidated the interlink

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af4d3a3b14a797939aa545fbc542e02
https://pubmed.ncbi.nlm.nih.gov/32304007

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Regression of Oxidative Stress by Targeting eNOS and Nrf2/ARE Signaling: A Guided Drug Target for Cardiovascular Diseases

Autor: Shanavas Syed Mohamed Puhari, Tharmarajan Ramprasath, Varadaraj Vasudevan, Sundaresan Sasikumar, Luciano Saso, Govindan Sadasivam Selvam

Publikováno v: Scopus-Elsevier

Cardiovascular diseases (CVDs) are the major health concern and the leading cause of death. Imbalance between free radicals and anti-oxidant defence is associated with cellular dysfunctions leading to the pathophysiology of various diseases including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb35680cde2b15b5aed17e2b4fca32bc
https://doi.org/10.2174/1568026615666150220114417

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