Increasing histone acetylation improves sociability and restores learning and memory in KAT6B-haploinsufficient mice.

Autor: Bergamasco MI; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Vanyai HK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Garnham AL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Geoghegan ND; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Vogel AP; Centre for Neurosciences of Speech, University of Melbourne, Parkville, Victoria, Australia.; Redenlab Inc., Melbourne, Australia., Eccles S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Rogers KL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia., Blewitt ME; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Hannan AJ; Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, Victoria, Australia., Thomas T; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Voss AK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Apr 01; Vol. 134 (7). Date of Electronic Publication: 2024 Apr 01.

The chromatin reader protein ING5 is required for normal hematopoietic cell numbers in the fetal liver.

Autor: Mah SYY; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Vanyai HK; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Yang Y; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Voss AK; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Thomas T; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 May 18; Vol. 14, pp. 1119750. Date of Electronic Publication: 2023 May 18 (Print Publication: 2023).

CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes.

Autor: White CW; Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, The Midlands, UK; Harry Perkins Institute of Medical Research and Centre for Medical Research, The University of Western Australia, QEII Medical Centre, Nedlands, WA 6009, Australia; Australian Research Council Centre for Personalised Therapeutics Technologies, Australia. Electronic address: carl.white@perkins.uwa.edu.au., Caspar B; Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, The Midlands, UK., Vanyai HK; Epithelial Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Pfleger KDG; Harry Perkins Institute of Medical Research and Centre for Medical Research, The University of Western Australia, QEII Medical Centre, Nedlands, WA 6009, Australia; Australian Research Council Centre for Personalised Therapeutics Technologies, Australia; Dimerix Limited, Nedlands, WA 6009, Australia., Hill SJ; Cell Signalling and Pharmacology Research Group, Division of Physiology, Pharmacology & Neuroscience, School of Life Sciences, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, The Midlands, UK; Harry Perkins Institute of Medical Research and Centre for Medical Research, The University of Western Australia, QEII Medical Centre, Nedlands, WA 6009, Australia. Electronic address: stephen.hill@nottingham.ac.uk.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2020 May 21; Vol. 27 (5), pp. 499-510.e7. Date of Electronic Publication: 2020 Feb 12.

A citizen science model for implementing statewide educational DNA barcoding.

Autor: Chiovitti A; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia.; School of Biosciences, University of Melbourne, Victoria, Australia., Thorpe F; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Gorman C; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Cuxson JL; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Robevska G; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Szwed C; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Duncan JC; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Vanyai HK; Gene Technology Access Centre (GTAC), The University High School, Parkville, Victoria, Australia., Cross J; Texas A&M University, College Station, Texas, United States of America., Siemering KR; Australian Genome Research Facility (AGRF), Victorian Comprehensive Cancer Centre, Melbourne, Victoria, Australia., Sumner J; Museums Victoria, Carlton Gardens, Victoria, Australia.

Publikováno v: PloS one [PLoS One] 2019 Jan 10; Vol. 14 (1), pp. e0208604. Date of Electronic Publication: 2019 Jan 10 (Print Publication: 2019).

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.

Autor: Baell JB; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia. Jonathan.Baell@monash.edu.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China. Jonathan.Baell@monash.edu., Leaver DJ; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Hermans SJ; ACRF Rational Drug Discovery Centre, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia., Kelly GL; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Brennan MS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Downer NL; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia., Nguyen N; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Wichmann J; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., McRae HM; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Yang Y; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Cleary B; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Lagiakos HR; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Mieruszynski S; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Pacini G; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia., Vanyai HK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Bergamasco MI; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., May RE; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia., Davey BK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Morgan KJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Sealey AJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Wang B; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; School of Pharmaceutical Sciences, Tsinghua University, Beijing, China., Zamudio N; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Wilcox S; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Garnham AL; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Sheikh BN; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Aubrey BJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Doggett K; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Chung MC; ACRF Rational Drug Discovery Centre, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia., de Silva M; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Bentley J; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Pilling P; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Hattarki M; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Dolezal O; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Dennis ML; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Falk H; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Ren B; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Charman SA; Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., White KL; Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia., Rautela J; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Newbold A; The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Hawkins ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Johnstone RW; The Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia., Huntington ND; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Peat TS; Commonwealth Scientific and Industrial Research Organisation (CSIRO), Biomedical Program, Parkville, Victoria, Australia., Heath JK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Strasser A; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Parker MW; ACRF Rational Drug Discovery Centre, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia., Street IP; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Monahan BJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Cancer Therapeutics CRC, Parkville, Victoria, Australia., Voss AK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia. avoss@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia. avoss@wehi.edu.au., Thomas T; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia. tthomas@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia. tthomas@wehi.edu.au.

Publikováno v: Nature [Nature] 2018 Aug; Vol. 560 (7717), pp. 253-257. Date of Electronic Publication: 2018 Aug 01.