Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vanya Peltekova"'
Autor:
Trevor D. McKee, Mark Zaidi, Lincoln Stein, Sebastian J. Schober, Katja Steiger, Olivier Delattre, Christopher M. Spring, Lawrence E. Heisler, Syed H.E. Zaidi, Hendrik Gassmann, John Douglas Mcpherson, M Orlic-Milacic, Eve Lapouble, P. Ruzanov, Vanya Peltekova, Poul H. Sorensen, Uwe Thiel, Stefan Burdach, Katja Specht, Valentina Evdokimova
SUMMARYEwing sarcoma (EwS) is an aggressive childhood malignancy with a high propensity for metastasis. By analyzing cohorts of patients and age-matched healthy donors, we establish that EwS metastatic progression is accompanied by elevated plasma le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ff93650dbee88f9c138ca8344c05f0
Autor:
Quang M. Trinh, Christina K. Yung, Raju Kucherlapati, Lincoln Stein, Hui Wen Yu, Minerva Fernandez, Donna M. Muzny, Tao Yuan, Richard A. Gibbs, Amy E. Roberts, Jiani C. Yin, Vanya Peltekova, Benjamin G. Neel, Erica Tworog-Dube, Jeffrey G. Reid, Margaret Morgan, Peng Chieh Chen, John Douglas Mcpherson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 31
Noonan syndrome (NS) is a relatively common genetic disorder, characterized by typical facies, short stature, developmental delay, and cardiac abnormalities. Known causative genes account for 70-80% of clinically diagnosed NS patients, but the geneti
Autor:
David J.A. D'Souza, John E. Dick, Ryszard Bielecki, Taryne Chong, Lyndsey Hodgson, Timothy Beck, Lincoln Stein, Jennifer Y. Y. Kwan, Mike Wang, Shawna Lee, Steven Gallinger, Aaron Pollett, Aamer Qazi, Marianne Rogers, Thomas J. Hudson, Krystian Kozak, Michelle Chan-Seng-Yue, Milica Volar, Colleen Ash, Syed H.E. Zaidi, Paul C. Boutros, Sasan Zandi, Jagadish Rangrej, Quang M. Trinh, Mathieu Lemire, Lee Timms, Robert Gryfe, John Douglas Mcpherson, Vanya Peltekova, Richard de Borja, Jianxin Wang, Brent W. Zanke
Publikováno v:
International Journal of Cancer; Vol 134
International Journal of Cancer. Journal International du Cancer
International journal of cancer, vol 134, iss 10
International Journal of Cancer. Journal International du Cancer
International journal of cancer, vol 134, iss 10
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at
Early Growth Response-1 Worsens Ventilator-induced Lung Injury by Up-Regulating Prostanoid Synthesis
Autor:
Martin Post, Brian P. Kavanagh, Vanya Peltekova, Nicola Ngiam, Doreen Engelberts, Gail Otulakowski
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 181:947-956
Ventilator-induced lung injury (VILI) is common and serious and may be mediated in part by prostanoids. We have demonstrated increased expression of the early growth response-1 (Egr1) gene by injurious ventilation, but whether-or how-such up-regulati
Autor:
Satoko Uematsu, Gail Otulakowski, Martin Post, Brian P. Kavanagh, Vanya Peltekova, Doreen Engelberts
Publikováno v:
Intensive Care Medicine. 36:869-878
Permissive hypercapnia is established in lung injury management. Therapeutic hypercapnia causes benefit or harm, depending on the context. Ventilator-associated lung injury has a wide spectrum of candidate mechanisms, affording multiple opportunities
Autor:
Martin Post, Brian P. Kavanagh, Doreen Engelberts, Colin McKerlie, Paul Babyn, Natalie Hopkins, Shinya Tsuchida, Paul McLoughlin, Helena Frndova, Vanya Peltekova
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 174:279-289
Many authors have suggested that the mechanism by which atelectasis contributes to injury is through the repetitive opening and closing of distal airways in lung regions that are atelectatic. However, neither the topographic nor mechanistic relations
Publikováno v:
The Journal of Nutrition. 130:578-584
We examined how cholecalciferol (vitamin D) nutrition affected serum 25-hydroxycholecalciferol (25(OH)D) and 1, 25-dihydroxycholecalciferol (1,25(OH)(2)D). Rats were fed conventional diet (vitamin D, 4.5 IU/g, or 7 nmol/d) or the same diet plus 18 nm
Autor:
Rowena Ridout, David E. C. Cole, Gillian A. Hawker, Laurence A. Rubin, Lynda J. Fielding, Vanya Peltekova
Publikováno v:
Journal of Bone and Mineral Research. 14:633-643
Peak bone mass has been shown to be a significant predictor of risk for osteoporosis. Previous studies have demonstrated that skeletal mass accumulation is under strong genetic control, and efforts have been made to identify candidate loci. Determina
Autor:
Reinhold Vieth, David M. Hwang, Laurence A. Rubin, Gillian A. Hawker, Vanya Peltekova, Jovan Evrovski, Choong-Chin Liew, David E. C. Cole, Geoffrey N. Hendy
Publikováno v:
The Lancet. 353:112-115
The regulation of extracellular calcium concentration by parathyroid hormone is mediated by a calcium-sensing, G-protein-coupled cell-surface receptor (CASR). Mutations of the CASR gene alter the set-point for extracellular ionised calcium [Ca2+]o an
Autor:
Laurence A. Rubin, David M. Hwang, N. Janicic, Choong-Chin Liew, Jovan Evrovski, Vanya Peltekova, Geoffrey N. Hendy, D E.C. Cole
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 57:122-125
The role that the Calcium Sensing Receptor (CASR) plays in extracellular calcium regulation had been ascertained through studies of inactivating as well as activating mutations of CASR gene in a number of multiplex families. We have extended these ob