Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vanthana Bharathi"'
Autor:
Michael F. Bode, Clare M. Schmedes, Grant J. Egnatz, Vanthana Bharathi, Yohei M. Hisada, David Martinez, Tomohiro Kawano, Alice Weithauser, Leah Rosenfeldt, Ursula Rauch, Joseph S. Palumbo, Silvio Antoniak, Nigel Mackman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice wit
Externí odkaz:
https://doaj.org/article/2196c66abee14dc480f8af601153009b
Autor:
Vanthana Bharathi, MBBS, Mishita Goel, MD, Xavier F. Pombar, DO, Sunita Nathan, MD, Tochukwu M. Okwuosa, DO
Publikováno v:
JACC: Case Reports, Vol 2, Iss 7, Pp 987-990 (2020)
We report the unique case of a patient who recovered cardiac function despite a history of doxorubicin-induced cardiomyopathy, chest radiation therapy, high dose chemotherapy post-allogeneic stem cell transplant, and triplet pregnancy. Data are spars
Externí odkaz:
https://doaj.org/article/9920a02f105041bb944903a70efa98ca
Autor:
Randall C. Gunther, Vanthana Bharathi, Stephen D. Miles, Lauryn R. Tumey, Clare M. Schmedes, Kohei Tatsumi, Meagan D. Bridges, David Martinez, Stephanie A. Montgomery, Melinda A. Beck, Eric Camerer, Nigel Mackman, Silvio Antoniak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInnate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activate
Externí odkaz:
https://doaj.org/article/9ce01fde26334c13975a5e0be80b3539
Autor:
Steven P. Grover, Vanthana Bharathi, Jens J. Posma, John H. Griffin, Joseph S. Palumbo, Nigel Mackman, Silvio Antoniak
Publikováno v:
Blood advances.
The chemotherapeutic drug doxorubicin is cardiotoxic and can cause irreversible heart failure. In addition to being cardiotoxic, doxorubicin also induces the activation of coagulation. We determined the effect of thrombin-mediated activation of prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a37647129d0740a83cd6beae5f0e1f
https://pubmed.ncbi.nlm.nih.gov/36477178
https://pubmed.ncbi.nlm.nih.gov/36477178
Autor:
David R. Martinez, Tomohiro Kawano, Ursula Rauch, Joseph S. Palumbo, Leah Rosenfeldt, Vanthana Bharathi, Silvio Antoniak, Clare M. Schmedes, Alice Weithauser, Grant J. Egnatz, Yohei Hisada, Michael Bode, Nigel Mackman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice with a globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332270258696a46894b5c1008ca1ed28
https://doaj.org/article/2196c66abee14dc480f8af601153009b
https://doaj.org/article/2196c66abee14dc480f8af601153009b
Autor:
Vanthana Bharathi, Kohei Tatsumi, Tracy Stokol, Nigel Mackman, Grant J. Egnatz, Alyson C. Auriemma, Silvio Antoniak, Joseph S. Palumbo, Melinda A. Beck, Clare M. Schmedes, John H. Griffin
Publikováno v:
Journal of Thrombosis and Haemostasis
Background Protease‐activated receptor 1 (PAR1) is expressed in various immune cells and in the lung. We showed that PAR1 plays a role in Coxsackievirus B3 infection by enhancing toll‐like receptor 3‐dependent interferon‐β expression in card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15d628d108303d9143b27114b1fa369
https://doi.org/10.1111/jth.15221
https://doi.org/10.1111/jth.15221
Autor:
Jesus Alfonso Catahay, Vanthana Bharathi, Andres Calderon, Kevin Arao, null Doctor, Asim Khan, Nabil Ghani
Publikováno v:
Endocrine Practice. 29:S118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cf1b5d4ad11afbd06f2191ca333830
https://doi.org/10.1016/j.eprac.2023.03.262
https://doi.org/10.1016/j.eprac.2023.03.262
Autor:
Stephen D Miles, Randall Gunther, Lauryn Tumey, Vanthana Bharathi, Nigel Mackman, Silvio Antoniak
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Proteinase-activated receptor 2 (PAR2) was shown to enhance proinflammatory toll-like receptor 3 (TLR3) responses, while dampening TLR3-dependent antiviral response in epithelial cells. Moreover, Par2 -/- mice exhibited improved survival after influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f7424a8ff5f676d98a3244e50f2ee6
https://doi.org/10.1161/atvb.42.suppl_1.474
https://doi.org/10.1161/atvb.42.suppl_1.474
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
The influenza A virus (IAV) causes a seasonal respiratory tract infection and is characterized by excessive inflammation and tissue pathology in the lungs. Protease-activated receptor 4 (PAR4) is expressed megakaryocytes/platelets, immune cells, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9faba99045c9bcf2bf245e68561bca9
https://doi.org/10.1161/atvb.42.suppl_1.337
https://doi.org/10.1161/atvb.42.suppl_1.337
Publikováno v:
JACC Case Reports
JACC: Case Reports, Vol 2, Iss 7, Pp 987-990 (2020)
JACC: Case Reports, Vol 2, Iss 7, Pp 987-990 (2020)
We report the unique case of a patient who recovered cardiac function despite a history of doxorubicin-induced cardiomyopathy, chest radiation therapy, high dose chemotherapy post-allogeneic stem cell transplant, and triplet pregnancy. Data are spars
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7795876e555d47f87db52cd54b73df
http://europepmc.org/articles/PMC8302090
http://europepmc.org/articles/PMC8302090