Bone morphogenetic protein signaling through ACVR1 and BMPR1A negatively regulates bone mass along with alterations in bone composition.

Autor: Shi C; Department of Oral Pathology, School and Hospital of Stomatology, Jilin University, 1500 Qinghua Road, Changchun 130000, China; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: ceshi@jlu.edu.cn., Mandair GS; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: gmandair@umich.edu., Zhang H; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: zhangho@umich.edu., Vanrenterghem GG; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: ggracevr@umich.edu., Ridella R; Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48108-1055, USA., Takahashi A; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: taakira@umich.edu., Zhang Y; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: yanshuaizhang2004@163.com., Kohn DH; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA; Biomedical Engineering College of Engineering, University of Michigan, MI 48109-2110, USA. Electronic address: dhkohn@umich.edu., Morris MD; Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48108-1055, USA. Electronic address: mdmorris@umich.edu., Mishina Y; Department of Biologic and Materials Sciences, University of Michigan, School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: mishina@umich.edu., Sun H; Department of Oral Pathology, School and Hospital of Stomatology, Jilin University, 1500 Qinghua Road, Changchun 130000, China. Electronic address: hcsun@mail.jlu.edu.cn.

Publikováno v: Journal of structural biology [J Struct Biol] 2018 Mar; Vol. 201 (3), pp. 237-246. Date of Electronic Publication: 2017 Nov 23.