IMPRESS: Improved methylation profiling using restriction enzymes and smMIP sequencing, combined with a new biomarker panel, creating a multi-cancer detection assay.

Autor: Vandenhoeck J; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Neefs I; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Vanpoucke T; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Ibrahim J; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Suls A; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium., Peeters D; Department of Pathology, Antwerp University Hospital and University of Antwerp, Edegem, Belgium., Schepers A; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium., Hoischen A; Department of Human Genetics and Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands.; Department of Internal Medicine and Radboud Centre for Infectious Diseases (RCI), Radboud University Medical Centre, Nijmegen, the Netherlands., Fransen E; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium., Peeters M; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Van Camp G; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium., Op de Beeck K; Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium. ken.opdebeeck@uantwerpen.be.; Centre for Oncological Research Antwerp (CORE), University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium. ken.opdebeeck@uantwerpen.be.

Publikováno v: British journal of cancer [Br J Cancer] 2024 Oct; Vol. 131 (7), pp. 1224-1236. Date of Electronic Publication: 2024 Aug 24.

IMPRESS: Improved Multiplex Methylation Profiling Using Restriction Enzymes and smMIP Sequencing for Highly Sensitive Multi-Cancer Detection

Autor: Neefs, I., Vandenhoeck, J., Vanpoucke, T., Ibrahim, J., Suls, A., Hoischen, A., Peeters, M., Op de Beeck, K., Van Camp, G.

Publikováno v: In The Journal of Liquid Biopsy November 2023 1 Supplement

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Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues.

Autor: Houben B; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Michiels E; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Ramakers M; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Konstantoulea K; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Louros N; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Verniers J; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., van der Kant R; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., De Vleeschouwer M; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Chicória N; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Vanpoucke T; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Gallardo R; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Schymkowitz J; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium., Rousseau F; Switch Laboratory, VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Cellular and Molecular Medicine, KULeuven, Leuven, Belgium.

Publikováno v: The EMBO journal [EMBO J] 2020 Jun 02; Vol. 39 (11), pp. e102864. Date of Electronic Publication: 2020 Apr 01.

Prognostic Impact of H19/Cell Adhesion Molecules Circuitry on Prostate Cancer Biopsy.

Autor: Pecci, Valeria, Pierconti, Francesco, Carlino, Angela, Pinto, Francesco, Gradilone, Ugo, De Martino, Sara, Rotili, Dante, Grassi, Claudio, Pontecorvi, Alfredo, Gaetano, Carlo, Strigari, Lidia, Farsetti, Antonella, Nanni, Simona

Publikováno v: Biomedicines; Oct2024, Vol. 12 Issue 10, p2322, 13p