Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vanniarajan Balamuralidhar"'
Autor:
Pradeep Bist, Wan Shoo Cheong, Aylwin Ng, Neha Dikshit, Bae-Hoon Kim, Niyas Kudukkil Pulloor, Hanif Javanmard Khameneh, Matija Hedl, Avinash R. Shenoy, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi S. Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John D. MacMicking, Ramnik J. Xavier, Bindu Sukumaran
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Prolonged NOD2 ligand engagement induces tolerance and attenuated NOD2 signalling, but the molecular mechanisms leading to this tolerance induction are unclear. Here the authors show that the degradation of a NOD2 adaptor, RIP2, by the E3 ligase ZNRF
Externí odkaz:
https://doaj.org/article/fcfe5f0cdf014198b141e4fc270fc775
Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
Autor:
Pradeep Bist, Wan Shoo Cheong, Aylwin Ng, Neha Dikshit, Bae Hoon Kim, Niyas Kudukkil Pulloor, Hanif Javanmard Khameneh, Matija Hedl, Avinash R. Shenoy, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi S. Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John D. MacMicking, Ramnik J. Xavier, Bindu Sukumaran
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8 Article number: 15865 (2017); Published: 28 June 2017; Updated: 18 August 2017 The previously published version of this Article contained a line number in the Abstract within the sentence ‘A fraction of RIP2 localizes to the
Externí odkaz:
https://doaj.org/article/ddffffb5080b4efba26d0571887e537d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Thuan Tong Tan, Neha Dikshit, A L Kwa, C Y Tang, Hanif Javanmard Khameneh, Sandeep D. Kale, Vanniarajan Balamuralidhar, Bindu Sukumaran, T P Lim, Pankaj Kumar, Alessandra Mortellaro
Publikováno v:
Mucosal Immunology. 11:257-272
The opportunistic Gram-negative bacterium Acinetobacter baumannii (AB) is a leading cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB belonging to international clones (ICs) I and II with limited treatment opti
Autor:
Hanif Javanmard Khameneh, Thuan Tong Tan, Tse Hsien Koh, Sandeep D. Kale, Alessandra Mortellaro, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Pankaj Kumar, Gladys Tan, Neha Dikshit, Bindu Sukumaran
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
Acinetobacter baumannii (A. baumannii) is a significant cause of severe nosocomial pneumonia in immunocompromised individuals world-wide. With limited treatment options available, a better understanding of host immnity to A. baumannii infection is cr
Autor:
Ramnik J. Xavier, Avinash R. Shenoy, Keh-Chuang Chin, Michelle Hong, Matija Hedl, Hanif Javanmard Khameneh, Clara Abraham, Pradeep Bist, Albert Neutzner, Alessandra Mortellaro, John D. MacMicking, Vanniarajan Balamuralidhar, Niyas Kudukkil Pulloor, Koichi Kobayashi, Najib Bin Abdul Malik, Wan Shoo Cheong, Antonio Bertoletti, Neha Dikshit, Bae Hoon Kim, Bindu Sukumaran, Aylwin Ng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Nature Communications
Optimal regulation of the innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is essential for controlling bacterial infections and inflammatory disorders. Chronic NOD2 stimulation induces non-responsiveness t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460a70ca5c17b4ba00ff764ae0c637c9
http://hdl.handle.net/10044/1/50102
http://hdl.handle.net/10044/1/50102
Autor:
Vanniarajan Balamuralidhar, Thet Tun Aung, Rayne R. Lim, Rajamani Lakshminarayanan, Padmanabhan Saraswathi, Roger W. Beuerman, Jamie Ya Ting Chang, Shouping Liu, Tse Siang Kang, Shyam S. Chaurasia, Jianguo Li, Neha Dikshit, J. Sivaraman, Bindu Sukumaran, Chandra S. Verma, Wei Xiang Tan, Nandhakumar Muruganantham, Eunice Tze Leng Goh
Publikováno v:
Scientific Reports
Dissecting the complexities of branched peptide-lipopolysaccharides (LPS) interactions provide rationale for the development of non-cytotoxic antibiotic adjuvants. Using various biophysical methods, we show that the branched peptide, B2088, binds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3745368d5ccd1d15ccf47e7e4343425a
https://hdl.handle.net/10356/84726
https://hdl.handle.net/10356/84726
Ubiquitination-mediated regulation of RIP2 in NOD2 signaling and MDP tolerance induction (INM2P.354)
Autor:
Bindu Sukumaran, pradeep bist, Aylwin Ng, Bae Hoon Kim, Niyas Kudukkil Pulloor, Hanif Khameneh, Matija Hedl, Neha Dikshit, Avinash Shenoy, Vanniarajan Balamuralidhar, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John MacMicking, Ramnik Xavier
Publikováno v:
The Journal of Immunology. 194:126.7-126.7
The cytoplasmic innate immune receptor NOD2 is required for antibacterial immune response. Optimal regulation of NOD2 is essential for controlling bacterial infections and inflammatory disorders. Recently, ubiquitination has emerged as an important p