Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vanmiddlesworth Frank L"'
Autor:
Claude Dufresne, Robert A. Reamer, Vanmiddlesworth Frank L, Otto D. Hensens, Deborah L. Zink, Jerrold M. Liesch
Publikováno v:
Tetrahedron Letters. 34:399-402
Structures of two novel fungal metabolites, zaragozic acids A (1) and B (2), characterized by a novel 2,8-dioxobicyclo[3.2.1] octane-4,6,7-trihydroxy-3,4,5-tricar☐ylic acid core, are proposed predominantly on the basis of 2D NMR.
Publikováno v:
ChemInform. 23
A new β-1,3 glucan synthesis inhibitor, L-687,781 is produced by the cultivation of Dictyochaeta simplex ATCC 20960. Through NMR, mass spectroscopy, and degradation studies the structure of L-687,781 was determined to be 1 , a novel member of the pa
Autor:
Robert E. Schwartz, Jerrold M. Liesch, Carol F. Wichmann, Kenneth E. Wilson, Vanmiddlesworth Frank L, Otto D. Hensens
Publikováno v:
ChemInform. 22
The structures and absolute stereochemistry of restricticin (1), its N,N-dimethyl derivative (4) and desglycyl hydrolysis product (3), isolated from Penicillium restrictum, have been determined on the basis of spectroscopic evidence. They belong to a
Publikováno v:
ChemInform. 24
Autor:
D Krupa, Charlotte Trainor, K Nollstadt, Robert E. Schwartz, James M. Balkovec, Vanmiddlesworth Frank L, Dennis M. Schmatz, Milton L. Hammond, Bartizal Kenneth F, George K. Abruzzo
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:1648-1657
The in vivo anti-Candida activities of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991 (cilofungin), L-687,901 (tetrahydroechinocandin B), and L-687,781 (a papulacandin analog) were evaluated by utilizing a murine model of disseminated ca
Autor:
Vanmiddlesworth Frank L, Robert A. Giacobbe, Kenneth E. Wilson, Ann M. Edison, George M. Garrity, Jon D. Polishook, Ken Bartizal, Richard L. Monaghan, Robert A. Fromtling, Marcia Zweerink, Lopez Maria B, Walter Rozdilsky, Judith A. Bland
Publikováno v:
The Journal of Antibiotics. 45:861-867
In screening for antifungal inhibitors from fungi, four related antifungal agents have been isolated from the cultivation of Aspergillus fumigatus ATCC 20857. These agents were initially produced by the microorganism growing on a solid millet-based m
Publikováno v:
Tetrahedron. 47:7563-7568
A new β-1,3 glucan synthesis inhibitor, L-687,781 is produced by the cultivation of Dictyochaeta simplex ATCC 20960. Through NMR, mass spectroscopy, and degradation studies the structure of L-687,781 was determined to be 1 , a novel member of the pa
Autor:
Robert E. Schwartz, Kenneth E. Wilson, Jerrold M. Liesch, Carol F. Wichmann, Otto D. Hensens, Vanmiddlesworth Frank L
Publikováno v:
Tetrahedron. 47:3915-3924
The structures and absolute stereochemistry of restricticin (1), its N,N-dimethyl derivative (4) and desglycyl hydrolysis product (3), isolated from Penicillium restrictum, have been determined on the basis of spectroscopic evidence. They belong to a
Autor:
Karl H. Nollstadt, M. A. Romancheck, Robert E. Schwartz, Kenneth E. Wilson, Vanmiddlesworth Frank L, Mervyn J. Turner, L. A. Pittarelli, Robert A. Fromtling, Dennis M. Schmatz
Publikováno v:
Proceedings of the National Academy of Sciences. 87:5950-5954
Pneumocystis carinii pneumonia is a major cause of death in AIDS patients in the United States. The presently available treatments have limited use due to a high incidence of adverse reactions. Therefore, there is an urgent need for a safer method fo
Autor:
Ken Bartizal, Art Patchett, George K. Abruzzo, Jan Onishi, Kenneth E. Wilson, Jim Milligan, Vanmiddlesworth Frank L, Claude Dufresne
Publikováno v:
The Journal of antibiotics. 49(3)