Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Vanitha N Sivalingam"'
Autor:
Neil A J Ryan, Raymond McMahon, Simon Tobi, Tristan Snowsill, Shona Esquibel, Andrew J Wallace, Sancha Bunstone, Naomi Bowers, Ioana E Mosneag, Sarah J Kitson, Helena O'Flynn, Neal C Ramchander, Vanitha N Sivalingam, Ian M Frayling, James Bolton, Rhona J McVey, D Gareth Evans, Emma J Crosbie
Publikováno v:
PLoS Medicine, Vol 17, Iss 9, p e1003263 (2020)
BackgroundLynch syndrome (LS) predisposes to endometrial cancer (EC), colorectal cancer, and other cancers through inherited pathogenic variants affecting mismatch-repair (MMR) genes. Diagnosing LS in women with EC can reduce subsequent cancer mortal
Externí odkaz:
https://doaj.org/article/eceb739d88234f0eb12072b08be0941f
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Pre-surgical window studies rely on the accurate quantification of biomarkers as surrogates of disease response. In endometrial cancer, this has traditionally involved comparing immunohistochemical expression in diagnostic endometrial biopsies with t
Externí odkaz:
https://doaj.org/article/aff93b75b30647f9b11c39048a605b72
Autor:
Emma J. Crosbie, Henry C. Kitchener, W. David Ryder, Joseph Shaw, Philip W. Pemberton, Richard J. Slade, Rahamatulla Latheef, Kyle Gilmour, Sean Burns, Saad Ali, Jennifer L. Allen, Vanitha N. Sivalingam, Zoe Maskell, Sarah J. Kitson
Immunohistochemistry staining protocols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ab8694cf7bee89d7f1ca48ac3f3d42
https://doi.org/10.1158/1078-0432.22471361.v1
https://doi.org/10.1158/1078-0432.22471361.v1
Autor:
Emma J. Crosbie, Henry C. Kitchener, W. David Ryder, Joseph Shaw, Philip W. Pemberton, Richard J. Slade, Rahamatulla Latheef, Kyle Gilmour, Sean Burns, Saad Ali, Jennifer L. Allen, Vanitha N. Sivalingam, Zoe Maskell, Sarah J. Kitson
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aedb79883eeb151c50db31289da530e
https://doi.org/10.1158/1078-0432.22471364
https://doi.org/10.1158/1078-0432.22471364
Autor:
Emma J. Crosbie, Henry C. Kitchener, W. David Ryder, Joseph Shaw, Philip W. Pemberton, Richard J. Slade, Rahamatulla Latheef, Kyle Gilmour, Sean Burns, Saad Ali, Jennifer L. Allen, Vanitha N. Sivalingam, Zoe Maskell, Sarah J. Kitson
Purpose:Endometrioid endometrial cancer is strongly associated with obesity and insulin resistance. Metformin, an insulin sensitizer, reduces endometrial tumor growth in vitro. Presurgical window studies allow rapid in vivo assessment of antitumor ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a0625798f85b0fada3a1fc80da235
https://doi.org/10.1158/1078-0432.c.6527864.v1
https://doi.org/10.1158/1078-0432.c.6527864.v1
Autor:
Vanitha N Sivalingam, Kajal K Tamber, John Newsham, Stephanie Ogden, Ursula Winters, Fiona M Walter, Richard Edmondson, Louise Gorman, Emma Crosbie
Publikováno v:
Vaginal and vulvar cancer.
Autor:
Maria Paraskevaidi, Camilo L. M. Morais, Katherine M. Ashton, Helen F. Stringfellow, Rhona J. McVey, Neil A. J. Ryan, Helena O’Flynn, Vanitha N. Sivalingam, Sarah J. Kitson, Michelle L. MacKintosh, Abigail E. Derbyshire, Cecilia Pow, Olivia Raglan, Kássio M. G. Lima, Maria Kyrgiou, Pierre L. Martin-Hirsch, Francis L. Martin, Emma J. Crosbie
Publikováno v:
Cancers, Vol 12, Iss 5, p 1256 (2020)
Endometrial cancer is the sixth most common cancer in women, with a rising incidence worldwide. Current approaches for the diagnosis and screening of endometrial cancer are invasive, expensive or of moderate diagnostic accuracy, limiting their clinic
Externí odkaz:
https://doaj.org/article/263d0b0fa64440ad9b755fb7c6abdb65
Autor:
J Newsham, K Tamber, U Winters, Richard J. Edmondson, FM Walter, S Ogden, Vanitha N Sivalingam, Emma J Crosbie
Publikováno v:
E-Posters.
Objectives Rates of vulvar cancer are increasing globally. Early detection reduces surgical morbidity and prolongs survival. Although population screening has no role, vulvar self-examination may prompt early diagnosis in high-risk women. UK guidance
Publikováno v:
Ruiz de Azua Unzurrunzaga, G, Brewster, D H, Wild, S & Sivalingam, V N 2019, ' Declining Hysterectomy Prevalence and the Estimated Impact on Uterine Cancer Incidence in Scotland ', Cancer Epidemiology, vol. 59, pp. 227-231 . https://doi.org/10.1016/j.canep.2019.02.008
Ruiz de Azua Unzurrunzaga, G, Brewster, D H, Wild, S H & Sivalingam, V N 2019, ' Declining hysterectomy prevalence and the estimated impact on uterine cancer incidence in Scotland ', Cancer Epidemiology, vol. 59, pp. 227-231 . https://doi.org/10.1016/j.canep.2019.02.008
Ruiz de Azua Unzurrunzaga, G, Brewster, D H, Wild, S H & Sivalingam, V N 2019, ' Declining hysterectomy prevalence and the estimated impact on uterine cancer incidence in Scotland ', Cancer Epidemiology, vol. 59, pp. 227-231 . https://doi.org/10.1016/j.canep.2019.02.008
AIM: The prevalence of hysterectomy is decreasing worldwide. It is not clear whether changes in the population at risk (women with intact uteruses) have contributed to an increased uterine cancer incidence. This study aims to assess the effect of cha
Autor:
R Davies, D Frimpong, Gemma L Owens, S Hawco, Dominic Blake, Sadie Jones, Vanitha N Sivalingam, M Abdelrahman, L Wan, Anna Collins, N Gomes, M Otify, T Khan, James Dilley, Eleanor K. Jones, N Ilenkovan, M Wilkinson, E Leung, P Sanderson, Linden Stocker, James P Beirne, Rasiah Bharathan, Laura Parnell, Neil A J Ryan, S. C. Wong, Michael P. Rimmer, M Farquharson
Publikováno v:
Poster.
Introduction Older patients undergoing cancer surgery are at increased risk of post-operative morbidity and mortality. Frailty is particularly prevalent in this patient cohort and is a major contributor to adverse outcomes. A survey was conducted to