Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vanitha Krishna Subbaiah"'
Autor:
Shobha Krishna Subbaiah, Vanitha Krishna Subbaiah, Mahantesha Sharanappa, Anirban Chatterjjee, Sreedevi Maddipati
Publikováno v:
Journal of Indian Society of Periodontology, Vol 26, Iss 1, Pp 13-18 (2022)
Background and Objectives: Periodontitis caused by multifactorial polymicrobial infection results in a destructive inflammatory process and loss of tooth supporting tissues. Many putative bacterial virulence factors that cause host destruction are re
Externí odkaz:
https://doaj.org/article/ec677dc368b84079bd85443b13aa3cfe
Autor:
Kazunori Nagasaka, Takayuki Seiki, Aki Yamashita, Paola Massimi, Vanitha Krishna Subbaiah, Miranda Thomas, Christian Kranjec, Kei Kawana, Shunsuke Nakagawa, Tetsu Yano, Yuji Taketani, Tomoyuki Fujii, Shiro Kozuma, Lawrence Banks
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53752 (2013)
Previous studies have shown that the cell polarity regulator hScrib interacts with, and consequently controls, the ERK signaling pathway. This interaction occurs through two well-conserved Kinase Interacting Motifs, which allow hScrib to bind ERK1 di
Externí odkaz:
https://doaj.org/article/45f0a6cc2a42441295e27e347cd5a114
Autor:
Vanitha Krishna Subbaiah, Paola Massimi, Siaw Shi Boon, Michael P Myers, Lisa Sharek, Rafael Garcia-Mata, Lawrence Banks
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002543 (2012)
A major target of the HPV E6 oncoprotein is the human Discs Large (hDlg) tumour suppressor, although how this interaction contributes to HPV-induced malignancy is still unclear. Using a proteomic approach we show that a strong interacting partner of
Externí odkaz:
https://doaj.org/article/e149b717c6e3473cb58c58cb60330248
Autor:
Edward Kai-Hua Chow, Sudhakar Jha, Tuan Zea Tan, Amit Kumar Pandey, Neerja Karnani, Shweta Pradip Jadhav, Yanzhou Zhang, Min Gong, Tan Boon Toh, Lissa Nurrul Abdullah, Jean Paul Thiery, Deepa Rajagopalan, Cheng Yong Tham, Vanitha Krishna Subbaiah
Publikováno v:
Journal of molecular cell biology. 8(5)
HIV-Tat-interacting protein of 60 kDa (TIP60) is a lysine acetyltransferase and known to be downregulated in multiple cancers. Among various signalling pathways, TIP60 is implicated in regulating epithelial-mesenchymal transition (EMT). Here, we show
Autor:
Ketaki Ganti, Paola Massimi, Lawrence Banks, Vjekoslav Tomaić, Miranda Thomas, Siaw Shi Boon, Vanitha Krishna Subbaiah, Christian Kranjec, Martina Bergant, David Pim
Publikováno v:
The FEBS Journal. 279:3530-3537
The human papillomavirus (HPV) E6 oncoprotein is fundamental to the ability of these viruses to induce human malignancy. A defining characteristic of the HPV E6 oncoproteins found in cancer-causing HPV types is the presence of a PDZ binding motif at
Autor:
Christian Kranjec, Kazunori Nagasaka, Paola Massimi, Miranda Thomas, Shunsuke Nakagawa, Vanitha Krishna Subbaiah, Lawrence Banks, Yuji Taketani, Vjekoslav Tomaić, Michael P. Myers, Tetsu Yano, David Pim
Publikováno v:
Oncogene. 29:5311-5321
The cell polarity regulator, human Scribble (hScrib), is a potential tumour suppressor whose loss is a frequent event in late-stage cancer development. Little is yet known about the mode of action of hScrib, although recent reports suggest its role i
Publikováno v:
International journal of cancer. 131(10)
The discs-large (DLG) tumor suppressor plays essential roles in regulating cell polarity and proliferation. It localizes at sites of cell-cell contact where it acts as a scaffold for multiple protein interactions, including with the adenomatous polyp
Publikováno v:
The Biochemical journal. 439(2)
Over 250 PDZ (PSD95/Dlg/ZO-1) domain-containing proteins have been described in the human proteome. As many of these possess multiple PDZ domains, the potential combinations of associations with proteins that possess PBMs (PDZ-binding motifs) are vas
Autor:
Vanitha Krishna Subbaiah, Shunsuke Nakagawa, Yuji Taketani, Paola Massimi, Tetsu Yano, Kazunori Nagasaka, David Pim, Lawrence Banks, Christian Kranjec
Publikováno v:
Small GTPases. 1(2)
Scribble is a potential tumor suppressor protein, whose loss is a frequent event in late stage cancer development. In both Drosophila and mammalian model systems, Scribble has been shown capable of regulating cell polarity, cell proliferation and apo
Autor:
Tomoyuki Fujii, Paola Massimi, Shiro Kozuma, Aki Yamashita, Takayuki Seiki, Kei Kawana, Christian Kranjec, Yuji Taketani, Lawrence Banks, Miranda Thomas, Vanitha Krishna Subbaiah, Kazunori Nagasaka, Tetsu Yano, Shunsuke Nakagawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53752 (2013)
PLoS ONE, Vol 8, Iss 1, p e53752 (2013)
Previous studies have shown that the cell polarity regulator hScrib interacts with, and consequently controls, the ERK signaling pathway. This interaction occurs through two well-conserved Kinase Interacting Motifs, which allow hScrib to bind ERK1 di