Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Vanishree Velamoor"'
Autor:
Vanishree Velamoor, Gergana Galabova-Kovacs, Florian Kern, Karin Ehrenreiter, Manuela Baccarini, Maria Sibilia, Katrin Meissl
Publikováno v:
Cancer Cell. 16:149-160
Ras activation is common to many human cancers and promotes cell proliferation and survival by initiating multiple signaling cascades. Accordingly, Ras-transformed cells are generally considered too resourceful to become addicted to a single effector
Autor:
J. Victor Small, Izabela Sobczak, Vanishree Velamoor, Daniela Piazzolla, Junji Takeda, Karin Ehrenreiter, Thomas Leung, Manuela Baccarini
Publikováno v:
The Journal of Cell Biology
Raf kinases relay signals inducing proliferation, differentiation, and survival. The Raf-1 isoform has been extensively studied as the upstream kinase linking Ras activation to the MEK/ERK module. Recently, however, genetic experiments have shown tha