Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vanida A. Jiyamapa-Serna"'
Autor:
Vanida A. Jiyamapa-Serna, David W. A. Beno, Stephen D. Hall, Michael R. Uhing, Raymond E. Galinsky, Robert E. Kimura, Yong Chen
Publikováno v:
Drug Metabolism and Disposition. 32:1325-1330
The purpose of this investigation was to examine the effects of surgery and anesthesia on in vivo CYP3A activity and portal venous blood flow. Midazolam, a CYP3A probe for both rats and humans, was administered orally (2.7 mg), intravenously (0.57 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823914beedada3d1aa9080393ee5be54
https://doi.org/10.1124/dmd.104.000927
https://doi.org/10.1124/dmd.104.000927
Autor:
Robert E. Kimura, David W. A. Beno, Vanida A. Jiyamapa-Serna, Yong Chen, Michael R. Uhing, Masakatsu Goto
Publikováno v:
Critical Care Medicine. 31:1154-1159
Objective To determine the effect of chronic exposure to endotoxin (lipopolysaccharide) and Staphylococcal enterotoxin B on hepatic injury and function. Design Prospective, controlled trial. Setting Research laboratory in a university hospital. Subje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc328560a9c6a27f648c2656090a563
https://doi.org/10.1097/01.ccm.0000060004.85054.f2
https://doi.org/10.1097/01.ccm.0000060004.85054.f2
Autor:
Robert E. Kimura, Vanida A. Jiyamapa-Serna, Michael R. Uhing, David W. A. Beno, Lucy V. Deriy
Publikováno v:
Shock. 17:312-315
The mechanism of liver injury in endotoxemia is unclear. Previous studies have shown that splenectomy protects the liver from endotoxin-induced injury. The purpose of this study was to determine the relationship of TNFalpha and IFNgamma release and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd5f295322fd9cac790da8eae8d8a54
https://doi.org/10.1097/00024382-200204000-00013
https://doi.org/10.1097/00024382-200204000-00013
Autor:
Yong Chen, David W. A. Beno, Vanida A. Jiyamapa-Serna, Robert E. Kimura, Michael R. Uhing, Masakatsu Goto
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 280:G866-G872
Most models of liver dysfunction in sepsis use endotoxin (lipopolysaccharide; LPS) to induce a pathophysiological response. In our study published in this issue (Beno DWA, Uhing MR, Goto M, Chen Y, Jiyamapa-Serna VA, and Kimura RE. Am J Physiol Gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb0bc79638a2df2bf8ff4ce3507b0c0
https://doi.org/10.1152/ajpgi.2001.280.5.g866
https://doi.org/10.1152/ajpgi.2001.280.5.g866
Autor:
M. A. Hamman, Raymond E. Galinsky, Yong Chen, Vanida A. Jiyamapa-Serna, Sara K. Quinney, Robert E. Kimura, Stephen D. Hall
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(6)
Itraconazole (ITZ) is a substrate of CYP3A and both ITZ and hydroxyitraconazole (OH-ITZ), a major metabolite formed by CYP3A, are potent inhibitors of CYP3A. The concentration- and time-dependent changes in the hepatic availability ( F H ) of ITZ wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4924051e129d8220242f2cc268fd44c
https://pubmed.ncbi.nlm.nih.gov/18339815
https://pubmed.ncbi.nlm.nih.gov/18339815
Autor:
Masakatsu Goto, David W. A. Beno, Yong Chen, Lucy V. Deriy, Robert E. Kimura, Michael R. Uhing, Vanida A. Jiyamapa-Serna, Ashwin Vasan
Publikováno v:
Shock (Augusta, Ga.). 19(4)
We have previously shown that systemic infusion of the bacterial toxins Staphylococcal enterotoxin B (SEB) and endotoxin (LPS) induces hepatic dysfunction as measured by decreased biliary indocyanine green (ICG) excretion. In this study, we compare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548add97d0824e1a51f0af733e0180c5
https://pubmed.ncbi.nlm.nih.gov/12688547
https://pubmed.ncbi.nlm.nih.gov/12688547
Autor:
Masakatsu Goto, Lucy V. Deriy, Vanida A. Jiyamapa-Serna, David W. A. Beno, Yong J. Chen, Robert E. Kimura, Michael R. Uhing
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 280(6)
Patients with severe trauma injury are transiently exposed to increased serum concentrations of tumor necrosis factor-alpha (TNF-alpha). These patients are susceptible to the development of multisystem organ failure (MSOF) triggered by subsequent exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cd37d2fc7e65a2cfe729f6ba5a9410
https://pubmed.ncbi.nlm.nih.gov/11356645
https://pubmed.ncbi.nlm.nih.gov/11356645
Autor:
David W. A. Beno, Michael R. Uhing, J Lloyd-Still, Vanida A. Jiyamapa-Serna, Robert E. Kimura
Publikováno v:
Journal of pediatric gastroenterology and nutrition. 32(3)
The objective of the study was to determine whether ursodeoxycholic acid (Ursodiol) is protective against ibuprofen (IBU)-induced enteropathy.Using the chronically catheterized rat model, IBU (60 mg/kg body weight per day) was infused via the gastric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7180d4acfa6110753070f3b9827167
https://pubmed.ncbi.nlm.nih.gov/11345174
https://pubmed.ncbi.nlm.nih.gov/11345174
Autor:
Robert E. Kimura, Michael R. Uhing, David W. A. Beno, Yong Chen, Masakatsu Goto, Vanida A. Jiyamapa-Serna
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 280(5)
Using a nonstressed chronically catheterized rat model in which the common bile duct was cannulated, we studied endotoxin-induced alterations in hepatic function by measuring changes in the maximal steady-state biliary excretion rate of the anionic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d746021a2a7051137142d5ddff0d53
https://pubmed.ncbi.nlm.nih.gov/11292593
https://pubmed.ncbi.nlm.nih.gov/11292593
Autor:
David W. A. Beno, Michael R. Uhing, Masakatsu Goto, Yong Chen, Vanida A. Jiyamapa-Serna, Robert E. Kimura
Publikováno v:
Critical Care Medicine; Apr2003, Vol. 31 Issue 4, p1154-1159, 6p