Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vania Y. Cao"'
Autor:
Vania Y. Cao, Surjeet Mastwal, Ming Ren, Rui M. Costa, Kuan Hong Wang, Yizhou Ye, Qing Liu, Matthew Coon
Publikováno v:
Neuron. 86(6):1385-1392
SummaryMotor behaviors recruit task-specific neuronal ensembles in motor cortices, which are consolidated over subsequent learning. However, little is known about the molecules that can identify the participating neurons and predict the outcomes of t
Publikováno v:
Journal of Visualized Experiments : JoVE
In vivo circuit and cellular level functional imaging is a critical tool for understanding the brain in action. High resolution imaging of mouse cortical neurons with two-photon microscopy has provided unique insights into cortical structure, functio
Publikováno v:
Journal of Visualized Experiments.
In vivo circuit and cellular level functional imaging is a critical tool for understanding the brain in action. High resolution imaging of mouse cortical neurons with two-photon microscopy has provided unique insights into cortical structure, functio
Autor:
Qing Liu, Surjeet Mastwal, Xinjian Li, Vania Y. Cao, Wenyu Zhang, Stephani Otte, Kuan Hong Wang
Publikováno v:
Journal of neuroscience methods. 291
Background In vivo optical imaging of neural activity provides important insights into brain functions at the single-cell level. Cranial windows and virally delivered calcium indicators are commonly used for imaging cortical activity through two-phot
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 10 (2016)
Frontiers in Neural Circuits, Vol 10 (2016)
Mental functions involve coordinated activities of specific neuronal ensembles that are embedded in complex brain circuits. Aberrant neuronal ensemble dynamics is thought to form the neurobiological basis of mental disorders. A major challenge in men
Autor:
Robert H. Wurtz, Rebecca A. Berman, James Cavanaugh, Kerry McAlonan, Kuan Hong Wang, Ilya E. Monosov, Edward S. Boyden, Vania Y. Cao, Mitchell K. Smith
Publikováno v:
PMC
SummaryA critical technique for understanding how neuronal activity contributes to behavior is determining whether perturbing it changes behavior. The advent of optogenetic techniques allows the immediately reversible alteration of neuronal activity
Autor:
Surjeet Mastwal, Abdel G. Elkahloun, Yizhou Ye, Qing Liu, Vania Y. Cao, Kuan Hong Wang, Wenyu Zhang, Ming Ren
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 27(7)
The activity-regulated gene Arc/Arg3.1 encodes a postsynaptic protein crucially involved in glutamatergic synaptic plasticity. Genetic mutations in Arc pathway and altered Arc expression in human frontal cortex have been associated with schizophrenia
Autor:
Vania Y. Cao, Manish C. Saraf, Stephen J. Benkovic, Gregory L. Moore, Nina M. Goodey, Costas D. Maranas
Publikováno v:
Biophysical Journal. 90:4167-4180
A number of computational approaches have been developed to reengineer promising chimeric proteins one at a time through targeted point mutations. In this article, we introduce the computational procedure IPRO (iterative protein redesign and optimiza
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(19)
The brain encodes information about past experience in specific populations of neurons that communicate with one another by firing action potentials. Studies of experience-dependent neural plasticity have largely focused on individual synaptic change
Publikováno v:
Journal of Visualized Experiments.
The brain's ability to change in response to experience is essential for healthy brain function, and abnormalities in this process contribute to a variety of brain disorders. To better understand the mechanisms by which brain circuits react to an ani