Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Vania F. Prado"'
Autor:
Sara Memar, Eric Jiang, Vania F. Prado, Lisa M. Saksida, Timothy J. Bussey, Marco A. M. Prado
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Open access to rodent cognitive data has lagged behind the rapid generation of large open-access datasets in other areas of neuroscience, such as neuroimaging and genomics. One contributing factor has been the absence of uniform standardizat
Externí odkaz:
https://doaj.org/article/1935e4365c724f179b5f09c6b0cbce55
Autor:
Miguel Skirzewski, Oren Princz-Lebel, Liliana German-Castelan, Alycia M. Crooks, Gerard Kyungwook Kim, Sophie Henke Tarnow, Amy Reichelt, Sara Memar, Daniel Palmer, Yulong Li, R. Jane Rylett, Lisa M. Saksida, Vania F. Prado, Marco A. M. Prado, Timothy J. Bussey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Nucleus accumbens cholinergic interneurons release acetylcholine and glutamate. Here, authors show that acetylcholine, rather than glutamate, is predominantly involved in updating dopamine dynamics mediating Pavlovian approach behaviours.
Externí odkaz:
https://doaj.org/article/f4d1dc4e75374f81957db4a31c2850f0
Autor:
Rachel E. Lackie, Jose Marques-Lopes, Valeriy G. Ostapchenko, Sarah Good, Wing-Yiu Choy, Patricija van Oosten-Hawle, Stephen H. Pasternak, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Molecular chaperones and co-chaperones, which are part of the protein quality control machinery, have been shown to regulate distinct aspects of Alzheimer’s Disease (AD) pathology in multiple ways. Notably, the co-chaperone STI1, which pre
Externí odkaz:
https://doaj.org/article/9ee481f80095427e8c20de5968f11484
Autor:
Daniela F. Goncalves, Monica S. Guzman, Robert Gros, André R. Massensini, Robert Bartha, Vania F. Prado, Marco A. M. Prado
Publikováno v:
ASN Neuro, Vol 12 (2020)
Acetylcholine (ACh) has been suggested to facilitate plasticity and improve functional recovery after different types of brain lesions. Interestingly, numerous studies have shown that striatal cholinergic interneurons are relatively resistant to acut
Externí odkaz:
https://doaj.org/article/fb55cbf335374cb6b3159a1b6e9c533d
Autor:
Kurt R. Lehner, Harold A. Silverman, Meghan E. Addorisio, Ashbeel Roy, Mohammed A. Al-Onaizi, Yaakov Levine, Peder S. Olofsson, Sangeeta S. Chavan, Robert Gros, Neil M. Nathanson, Yousef Al-Abed, Christine N. Metz, Vania F. Prado, Marco A. M. Prado, Kevin J. Tracey, Valentin A. Pavlov
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The brain regulates physiological functions integral to survival. However, the insight into brain neuronal regulation of peripheral immune function and the neuromediator systems and pathways involved remains limited. Here, utilizing selective genetic
Externí odkaz:
https://doaj.org/article/9429fd2bb29d48c2bd224db6663e80e6
Autor:
Giuseppe Gangarossa, Monica Guzman, Vania F. Prado, Marco A.M. Prado, Stephanie Daumas, Salah El Mestikawy, Emmanuel Valjent
Publikováno v:
Neurobiology of Disease, Vol 87, Iss , Pp 69-79 (2016)
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons. The gold standard therapy relies on dopamine (DA) replacement by the administration of levodopa (l-DOPA). However, with time l-DOPA treatment induces severe motor
Externí odkaz:
https://doaj.org/article/3ec9c535796643b995440f350a920dc9
Autor:
Flavio H. Beraldo, Anu Thomas, Benjamin Kolisnyk, Pedro H. Hirata, Xavier De Jaeger, Amanda C. Martyn, Jue Fan, Daniela F. Goncalves, Matthew F. Cowan, Talal Masood, Vilma R. Martins, Robert Gros, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 11, Pp 1457-1466 (2015)
Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90 exchange of client proteins, but it can also be secreted to trigger prion protein-mediated neuronal signaling. Some mothers of children with autism sp
Externí odkaz:
https://doaj.org/article/d92dfd7a39ac4bbfa533c0c083604adc
Autor:
Luiz O.S. Leiria, Fernanda M. Arantes-Costa, Marina C. Calixto, Eduardo C. Alexandre, Rodrigo F. Moura, Franco Folli, Carla M. Prado, Marco Antonio Prado, Vania F. Prado, Licio A. Velloso, José Donato Jr., Edson Antunes, Milton A. Martins, Mario J.A. Saad
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 934-943 (2015)
Obesity is a major risk factor for asthma, which is characterized by airway hyperreactivity (AHR). In obesity-associated asthma, AHR may be regulated by non-TH2 mechanisms. We hypothesized that airway reactivity is regulated by insulin in the CNS, an
Externí odkaz:
https://doaj.org/article/e62ac39151124fa3ae3ee0ce36d19a1f
Autor:
Rachel E. Lackie, Andrzej Maciejewski, Valeriy G. Ostapchenko, Jose Marques-Lopes, Wing-Yiu Choy, Martin L. Duennwald, Vania F. Prado, Marco A. M. Prado
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaqu
Externí odkaz:
https://doaj.org/article/f10efba2407246aaabc056b22a623b95
Autor:
Stephanie Tullo, Aline S Miranda, Esther del Cid-Pellitero, Mei Peng Lim, Daniel Gallino, Anoosha Attaran, Raihaan Patel, Vladislav Novikov, Megan Park, Flavio H. Beraldo, Wen Luo, Irina Shlaifer, Thomas M. Durcan, Timothy J. Bussey, Lisa M. Saksida, Edward A. Fon, Vania F. Prado, Marco A.M. Prado, M. Mallar Chakravarty
There is significant evidence suggesting aggregated misfolded alpha-synuclein, a major component of Lewy bodies, propagates in a prion-like manner contributing to disease progression in Parkinson’s disease (PD) and other synucleinopathies. Animal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1551978d46642e96305cc28592344d79
https://doi.org/10.1101/2022.10.12.511820
https://doi.org/10.1101/2022.10.12.511820