Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Vania F Prado"'
Autor:
Flavio H Beraldo, Daniel Palmer, Sara Memar, David I Wasserman, Wai-Jane V Lee, Shuai Liang, Samantha D Creighton, Benjamin Kolisnyk, Matthew F Cowan, Justin Mels, Talal S Masood, Chris Fodor, Mohammed A Al-Onaizi, Robert Bartha, Tom Gee, Lisa M Saksida, Timothy J Bussey, Stephen S Strother, Vania F Prado, Boyer D Winters, Marco AM Prado
Publikováno v:
eLife, Vol 8 (2019)
Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the availability of tools to share and disseminate data is scarce.
Externí odkaz:
https://doaj.org/article/eb34ca1f433b461497974bd568a6446d
Autor:
Sudesna Chakraborty, Roy A. M. Haast, Kate M. Onuska, Prabesh Kanel, Marco A. M. Prado, Vania F. Prado, Ali R. Khan, Taylor W. Schmitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cortical cholinergic projections originate from subregions of the basal forebrain (BF). To examine its organization in humans, we computed multimodal gradients of BF connectivity by combining 7 T diffusion and resting state functional MRI. M
Externí odkaz:
https://doaj.org/article/4309096a79a2481a992268a71e9788f8
Autor:
Jake Bedore, Amanda C Martyn, Anson K C Li, Eric A Dolinar, Ian S McDonald, Stuart G Coupland, Vania F Prado, Marco A Prado, Kathleen A Hill
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133989 (2015)
Despite rigorous characterization of the role of acetylcholine in retinal development, long-term effects of its absence as a neurotransmitter are unknown. One of the unanswered questions is how acetylcholine contributes to the functional capacity of
Externí odkaz:
https://doaj.org/article/163d5fa3df054a47a6587f6d007b3ac2
Autor:
Ashbeel Roy, Aline Lara, Diogo Guimarães, Rita Pires, Eneas R Gomes, David E Carter, Marcus V Gomez, Silvia Guatimosim, Vania F Prado, Marco A M Prado, Robert Gros
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39997 (2012)
Autonomic dysfunction is observed in many cardiovascular diseases and contributes to cardiac remodeling and heart disease. We previously reported that a decrease in the expression levels of the vesicular acetylcholine transporter (VAChT) in genetical
Externí odkaz:
https://doaj.org/article/5914918505cb42bc87b9df72c5e4d88c
Autor:
Monica S Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A Souza, Alex X Li, Susanne Schmid, Ravi S Menon, Raul R Gainetdinov, Marc G Caron, Robert Bartha, Vania F Prado, Marco A M Prado
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001194 (2011)
Cholinergic neurons in the striatum are thought to play major regulatory functions in motor behaviour and reward. These neurons express two vesicular transporters that can load either acetylcholine or glutamate into synaptic vesicles. Consequently ch
Externí odkaz:
https://doaj.org/article/b8e704cc8e744454b8e838e381964c94
Autor:
Cristina Martins-Silva, Xavier De Jaeger, Monica S Guzman, Ricardo D F Lima, Magda S Santos, Christopher Kushmerick, Marcus V Gomez, Marc G Caron, Marco A M Prado, Vania F Prado
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17611 (2011)
Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly because of the difficulty in generating suitable animal models of cholinergic dysfunction. We have recently shown that, by targeting the vesicular acetylcho
Externí odkaz:
https://doaj.org/article/4ac73b1ec9294da192a0874c76d99dd4
Autor:
Sara Memar, Eric Jiang, Vania F. Prado, Lisa M. Saksida, Timothy J. Bussey, Marco A. M. Prado
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Open access to rodent cognitive data has lagged behind the rapid generation of large open-access datasets in other areas of neuroscience, such as neuroimaging and genomics. One contributing factor has been the absence of uniform standardizat
Externí odkaz:
https://doaj.org/article/1935e4365c724f179b5f09c6b0cbce55
Autor:
Miguel Skirzewski, Oren Princz-Lebel, Liliana German-Castelan, Alycia M. Crooks, Gerard Kyungwook Kim, Sophie Henke Tarnow, Amy Reichelt, Sara Memar, Daniel Palmer, Yulong Li, R. Jane Rylett, Lisa M. Saksida, Vania F. Prado, Marco A. M. Prado, Timothy J. Bussey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Nucleus accumbens cholinergic interneurons release acetylcholine and glutamate. Here, authors show that acetylcholine, rather than glutamate, is predominantly involved in updating dopamine dynamics mediating Pavlovian approach behaviours.
Externí odkaz:
https://doaj.org/article/f4d1dc4e75374f81957db4a31c2850f0
Autor:
Giuseppe Gangarossa, Monica Guzman, Vania F. Prado, Marco A.M. Prado, Stephanie Daumas, Salah El Mestikawy, Emmanuel Valjent
Publikováno v:
Neurobiology of Disease, Vol 87, Iss , Pp 69-79 (2016)
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons. The gold standard therapy relies on dopamine (DA) replacement by the administration of levodopa (l-DOPA). However, with time l-DOPA treatment induces severe motor
Externí odkaz:
https://doaj.org/article/3ec9c535796643b995440f350a920dc9
Autor:
Marco A. M. Prado, Vania F. Prado, Monica S. Guzman, Helena Janickova, Mohammed A. Al-Onaizi, Ornela Kljakic, Kevin S. Chen
Publikováno v:
European Journal of Neuroscience. 54:6075-6092
Disruptions in social behaviour are prevalent in many neuropsychiatric disorders such as schizophrenia, bipolar disorder and autism spectrum disorders. However, the underlying neurochemical regulation of social behaviour is still not well understood.