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pro vyhledávání: '"Vania Bertrand"'
Autor:
Vania Bertrand, Alessia Bachmann, Massimo Morbidelli, Miroslav Soos, Katia Cantalupo, Daniel J. Karst
Publikováno v:
Biotechnology and Bioengineering. 116:1959-1972
Long-term continuous protein production can be reached by perfusion operation. Through the continuous removal of waste metabolites and supply of nutrients, steady-state (SS) conditions are achieved after a certain transient period, where the conditio
Autor:
Vania Bertrand, Sebastian Vogg, Massimo Morbidelli, Matthieu Stettler, Miroslav Soos, Hervé Broly, Thomas K. Villiger
Publikováno v:
Journal of Biotechnology. 279:27-36
The pharmaceutical production of recombinant proteins, such as monoclonal antibodies, is rather complex and requires proper development work. Accordingly, it is essential to develop appropriate scale-down models, which can mimic the corresponding pro
Publikováno v:
New Biotechnology. 33:S42