Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Vani Nilakantan"'
Autor:
Vani Nilakantan, Maharaj Singh, Ruth M. Perez, Yang Shi, Ahmed Dalmar, Brittany T. Last, Ajay Sahajpal
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 3, Iss 1, Pp 9-19 (2016)
Purpose: Kidney transplantation remains the best treatment option for end-stage renal disease. However, despite overall improvements in patient and graft survival rates after kidney transplantation, differences in outcomes still exist among different
Externí odkaz:
https://doaj.org/article/ab1a749422654a70b78ecb1ab0827e2e
Publikováno v:
Computers in Biology and Medicine. 116:103580
Acute kidney injury (AKI) commonly occurs in hospitalized patients and can lead to serious medical complications. But it is preventable and potentially reversible with early diagnosis and management. Therefore, several machine learning based predicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9629ba774f480c178520203483968015
https://doi.org/10.1016/j.compbiomed.2019.103580
https://doi.org/10.1016/j.compbiomed.2019.103580
Autor:
Richard J. Roman, Jordan Mortensen, Sarah M. White, Kevin R. Regner, Vani Nilakantan, Brian D. Shames, Robert P. Ryan
Publikováno v:
Journal of Surgical Research. 164:e291-e297
Background Improved kidney preservation methods are needed to reduce ischemia-reperfusion (IR) injury in kidney allografts. Lifor is an artificial preservation solution comprised of nutrients, growth factors, and a non-protein oxygen and nutrient car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d27f7ffbe48c75d03d9691ecb338ad9
https://doi.org/10.1016/j.jss.2010.08.033
https://doi.org/10.1016/j.jss.2010.08.033
Publikováno v:
Free Radical Biology and Medicine. 49:1550-1560
Generation of excessive reactive oxygen species (ROS) leads to mitochondrial dysfunction, apoptosis, and necrosis in renal ischemia-reperfusion (IR) injury. Previously we showed that lentiviral vector-mediated overexpression of superoxide dismutase-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15fa9a96e3bacd74db002dc63c58c5b
https://doi.org/10.1016/j.freeradbiomed.2010.08.018
https://doi.org/10.1016/j.freeradbiomed.2010.08.018
Publikováno v:
Molecular and Cellular Biochemistry. 335:211-222
The role of mitochondrial K(ATP) (mitoK(ATP)) channels in renal ischemia-reperfusion injury is controversial with studies showing both protective and deleterious effects. In this study, we compared the effects of the putative mitoK(ATP) opener, diazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e48c2104b63b02fe6dac5480d22265f
https://doi.org/10.1007/s11010-009-0271-6
https://doi.org/10.1007/s11010-009-0271-6
Publikováno v:
American Journal of Physiology-Renal Physiology. 294:F562-F570
20-HETE, a metabolite of arachidonic acid, has been implicated as a mediator of free radical formation and tissue death following ischemia-reperfusion (IR) injury in the brain and heart. The present study examined the role of this pathway in a simula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63674917f873b8a332cbe3eb953d41f4
https://doi.org/10.1152/ajprenal.00387.2007
https://doi.org/10.1152/ajprenal.00387.2007
Oxidant-mediated apoptosis in proximal tubular epithelial cells following ATP depletion and recovery
Autor:
Cheryl J. Maenpaa, Scott K. Van Why, Brian D. Shames, Vani Nilakantan, Christopher P. Johnson
Publikováno v:
Free Radical Biology and Medicine. 44:518-526
Oxidant-mediated apoptosis has been implicated in renal injury due to ischemia reperfusion (IR); however, the apoptotic signaling pathways following IR have been incompletely defined. The purpose of this study was to examine the role of oxidants on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d379bc091924417ed6dd7c1c42af07bb
https://doi.org/10.1016/j.freeradbiomed.2007.10.040
https://doi.org/10.1016/j.freeradbiomed.2007.10.040
Autor:
Yixin Li, Job C. Tharappel, Brett T. Spear, Howard P. Glauert, Vani Nilakantan, Michelle L. Twaroski, Karen Calfee-Mason
Publikováno v:
PPAR Research, Vol 2008 (2008)
In this review, the role of NF-κB in the induction of hepatocarcinogenesis by peroxisome proliferators is examined. The administration of peroxisome proliferators for more than a three-day period leads to the activation of NF-κB in the livers of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112d755937e18d66eced1a91113eccbc
https://doi.org/10.1155/2008/286249
https://doi.org/10.1155/2008/286249
Autor:
Gail Hilton, Brian D. Shames, Christopher P. Johnson, Scott K. Van Why, Vani Nilakantan, Cheryl J. Maenpaa, Galen M. Pieper
Publikováno v:
Molecular and Cellular Biochemistry. 304:1-11
Oxidative stress is important in the pathogenesis of renal ischemia-reperfusion (IR) injury; however whether imbalances in reactive oxygen production and disposal account for susceptibility to injury is unclear. The purpose of this study was to compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a5cd55ac338c64dee392117a1dca18
https://doi.org/10.1007/s11010-007-9480-z
https://doi.org/10.1007/s11010-007-9480-z
Publikováno v:
The Journal of Heart and Lung Transplantation. 25:707-715
Anti-oxidant vitamins have increasingly been used to supplement traditional post-surgical treatment in cardiac transplant recipients. However, the mechanism(s) of action have not been determined. In this study we examined the effects of a novel vitam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21d196d558ca16e22245572c162a961
https://doi.org/10.1016/j.healun.2006.02.007
https://doi.org/10.1016/j.healun.2006.02.007