Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vangala G. Saipradeep"'
Autor:
Sarah L. Stenton, Melanie C. O’Leary, Gabrielle Lemire, Grace E. VanNoy, Stephanie DiTroia, Vijay S. Ganesh, Emily Groopman, Emily O’Heir, Brian Mangilog, Ikeoluwa Osei-Owusu, Lynn S. Pais, Jillian Serrano, Moriel Singer-Berk, Ben Weisburd, Michael W. Wilson, Christina Austin-Tse, Marwa Abdelhakim, Azza Althagafi, Giulia Babbi, Riccardo Bellazzi, Samuele Bovo, Maria Giulia Carta, Rita Casadio, Pieter-Jan Coenen, Federica De Paoli, Matteo Floris, Manavalan Gajapathy, Robert Hoehndorf, Julius O. B. Jacobsen, Thomas Joseph, Akash Kamandula, Panagiotis Katsonis, Cyrielle Kint, Olivier Lichtarge, Ivan Limongelli, Yulan Lu, Paolo Magni, Tarun Karthik Kumar Mamidi, Pier Luigi Martelli, Marta Mulargia, Giovanna Nicora, Keith Nykamp, Vikas Pejaver, Yisu Peng, Thi Hong Cam Pham, Maurizio S. Podda, Aditya Rao, Ettore Rizzo, Vangala G. Saipradeep, Castrense Savojardo, Peter Schols, Yang Shen, Naveen Sivadasan, Damian Smedley, Dorian Soru, Rajgopal Srinivasan, Yuanfei Sun, Uma Sunderam, Wuwei Tan, Naina Tiwari, Xiao Wang, Yaqiong Wang, Amanda Williams, Elizabeth A. Worthey, Rujie Yin, Yuning You, Daniel Zeiberg, Susanna Zucca, Constantina Bakolitsa, Steven E. Brenner, Stephanie M. Fullerton, Predrag Radivojac, Heidi L. Rehm, Anne O’Donnell-Luria
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-25 (2024)
Abstract Background A major obstacle faced by families with rare diseases is obtaining a genetic diagnosis. The average "diagnostic odyssey" lasts over five years and causal variants are identified in under 50%, even when capturing variants genome-wi
Externí odkaz:
https://doaj.org/article/29fbe7d26d88463789f004c8908aa4a7
Autor:
Aditya Rao, Thomas Joseph, Vangala G Saipradeep, Sujatha Kotte, Naveen Sivadasan, Rajgopal Srinivasan
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231728 (2020)
IntroductionPhenotype-driven rare disease gene prioritization relies on high quality curated resources containing disease, gene and phenotype annotations. However, the effectiveness of gene prioritization tools is constrained by the incomplete covera
Externí odkaz:
https://doaj.org/article/223c1bbf46bc4a2aadb4a443644a9360
Autor:
Zhiqiang Hu, Jesse M. Hunter, Olivier Lichtarge, Sean D. Mooney, Aashish N. Adhikari, Steven E. Brenner, Rita Casadio, Yizhou Yin, Lipika R. Pal, Uma Sunderam, Panagiotis Katsonis, Predrag Radivojac, Thomas Joseph, Giulia Babbi, Naveen Sivadasan, Constantina Bakolitsa, Vangala G. Saipradeep, Laura Kasak, John Moult, Julian Gough, M. Stephen Meyn, Pier Luigi Martelli, Jennifer Poitras, Rupa A Udani, Jan Zaucha, Rafael F. Guerrero, Yuxiang Jiang, Aditya Rao, Sujatha Kotte, Kunal Kundu
Publikováno v:
Hum Mutat
Whole-genome sequencing (WGS) holds great potential as a diagnostic test. However, the majority of patients currently undergoing WGS lack a molecular diagnosis, largely due to the vast number of undiscovered disease genes and our inability to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d965f4678b430bbf6815058eecb3cdf6
https://doi.org/10.1002/humu.23874
https://doi.org/10.1002/humu.23874
Autor:
Matthew G. Jones, Lu Han, Naveen Sivadasan, Thomas Joseph, Alex Khodaverdian, Robert Y. Wang, Michael B. Elowitz, Phil Rennert, Il Youp Kwak, Hanrui Zhang, Vangala G. Saipradeep, Daniel J. Garry, Zhandong Liu, Alejandro A. Granados, Maximilian J. Telford, Augustinas Prusokas, Thomas Yu, Aditya Rao, Michael Mason, Suhas Rao, Pablo Meyer, Jay Shendure, Irepan Salvador-Martínez, Ehud Shapiro, Wuming Gong, Richard Zhang, Rajgopal Srinivasan, Renata Retkute, Alidivinas Prusokas, Yuanfang Guan, Ofir Raz, Jingyuan Hu, Nir Yosef, Jiajie Peng, Ke Huan K. Chow, Verena Chung, Xuequn Shang
Publikováno v:
Cell Systems
Summary The recent advent of CRISPR and other molecular tools enabled the reconstruction of cell lineages based on induced DNA mutations and promises to solve the ones of more complex organisms. To date, no lineage reconstruction algorithms have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7aacc91f7306dd847d3ec3e17fe72a
https://pubmed.ncbi.nlm.nih.gov/34146472
https://pubmed.ncbi.nlm.nih.gov/34146472
Autor:
Rajgopal Srinivasan, Vangala G. Saipradeep, Aditya Rao, Sujatha Kotte, Thomas Joseph, Naveen Sivadasan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0231728 (2020)
PLoS ONE, Vol 15, Iss 4, p e0231728 (2020)
IntroductionPhenotype-driven rare disease gene prioritization relies on high quality curated resources containing disease, gene and phenotype annotations. However, the effectiveness of gene prioritization tools is constrained by the incomplete covera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb45935a56f5a9b5b9728e6ca2566c2
https://doi.org/10.1371/journal.pone.0231728
https://doi.org/10.1371/journal.pone.0231728
Publikováno v:
BIBM
Introduction: Search of MEDLINE using the PUBMED interface still remains a preferred approach for many scientists, even in the presence of alternatives. While PUBMED provides a rich interface for querying, it does not provide deep analysis of the que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0d706c7db28caf430fe3741630a8e54
https://doi.org/10.1109/bibm.2015.7359934
https://doi.org/10.1109/bibm.2015.7359934
Publikováno v:
BIBM
Background: Text-processing of unstructured biomedical text has become crucial to pharma companies, both with regards to legacy as well as topical documentation. The Apache Unstructured Information Management Applications (UIMA) framework addresses g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b71f6dffd11e9d8248e51bd7a80246f
https://doi.org/10.1109/bibm.2015.7359958
https://doi.org/10.1109/bibm.2015.7359958
Autor:
Naveen Sivadasan, Thomas Joseph, Rajgopal Srinivasan, Sujatha Kotte, Aditya Rao, Vangala G. Saipradeep, Ganesh Sekar Venkat Raghavan
Publikováno v:
Bioinformation
TPX is a web-based PubMed search enhancement tool that enables faster article searching using analysis and exploration features. These features include identification of relevant biomedical concepts from search results with linkouts to source databas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766d4c683ed1f96c7619b4cf5c0a256b
https://doi.org/10.6026/97320630008578
https://doi.org/10.6026/97320630008578
Autor:
Rajgopal Srinivasan, Thomas Joseph, Sri Jyothsna Yeleswarapu, Vangala G. Saipradeep, Aditya Rao
Publikováno v:
BMC Medical Informatics and Decision Making
Background Pharmacovigilance aims to uncover and understand harmful side-effects of drugs, termed adverse events (AEs). Although the current process of pharmacovigilance is very systematic, the increasing amount of information available in specialize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c59866b9c8c2565ba8f430648c8bf39
https://pubmed.ncbi.nlm.nih.gov/24559132
https://pubmed.ncbi.nlm.nih.gov/24559132