Výsledky vyhledávání - "Vanessa de V. C. Sinatti"

Computational evaluation of natural compounds as potential inhibitors of human PEPCK-M: an alternative for lung cancer therapy

Autor: Ana Carolina Ramos Guimarães, Luiz Phillippe R. Baptista, Vanessa de V. C. Sinatti, João Hermínio Martins da Silva, Laurent E. Dardenne

Publikováno v: Advances and Applications in Bioinformatics and Chemistry. 12:15-32

Background Lung cancer is the leading cause of cancer-related death worldwide. Among its subtypes, non-small cell lung cancer (NSCLC) is the most common. Recently, the mitochondrial isoform of the enzyme phosphoenolpyruvate carboxykinase (HsPEPCK-M)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46902cb5d810d99a26e5774c064abc7e
https://doi.org/10.2147/aabc.s197119

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In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches

Autor: Ana Carolina Ramos Guimarães, João Hermínio Martins da Silva, Luiz Phillippe R. Baptista, Laurent E. Dardenne, Vanessa de V. C. Sinatti, Marcelo Alves-Ferreira

Publikováno v: Journal of Molecular Graphics and Modelling. 77:168-180

Chagas disease, caused by the protozoan Trypanosoma cruzi, affects approximately seven million people, mainly in Latin America, and causes about 7000 deaths annually. The available treatments are unsatisfactory and search for more effective drugs aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998df8f783a6352092d65479b3dade20
https://doi.org/10.1016/j.jmgm.2017.08.007

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