Plasmodium translocon component EXP2 facilitates hepatocyte invasion

Autor: João Mello-Vieira, Maria M. Mota, Vanessa Zuzarte-Luis, Tania F. de Koning-Ward, Francisco J. Enguita

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications

© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af392e6ef80ede222bc4a3b5f2d36376
http://link.springer.com/article/10.1038/s41467-020-19492-4

IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria

Autor: Vanessa Zuzarte-Luis, Maria Regina D'Império-Lima, Érika Machado de Salles, Flávia Vieira, Sabrina Epiphanio, Maria N. de Menezes, José M. Alvarez, Alexandra dos Anjos Cassado, Maria M. Mota, José C. Alves-Filho, Eduardo P. Amaral

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Malaria causes hepatic inflammation and damage, which contribute to disease severity. The pro-inflammatory cytokine interleukin (IL)-1α is released by non-hematopoietic or hematopoietic cells during liver injury. This study established the role of I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98ea553cd8f808b742d69ea21629a4a
http://link.springer.com/article/10.1038/s41598-019-44125-2

Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development

Autor: Tabish A. Syed, Varadharajan Sundaramurthy, Harish Ranga-prasad, Tobias Furstenhaupt, Jana Meissner, Lakshmi Balasubramanian, Vanessa Zuzarte-Luis, Cecília M. P. Rodrigues, Saptarathi Deb, Ana S. Almeida, Maria M. Mota, Miguel Prudêncio, Kaleem Siddiqi, Debakshi Mullick

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 9 (2020)

Plasmodium parasites undergo a dramatic transformation during the liver stage of their life cycle, amplifying over 10,000-fold inside infected hepatocytes within a few days. Such a rapid growth requires large-scale interactions with, and manipulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbb50ec1a3cb9350b18d1f2c6b923bc
https://www.frontiersin.org/article/10.3389/fcimb.2019.00451/full

Fighting for Resources: Who Started the Battle? Who Is Winning It?

Autor: Maria M. Mota, Vanessa Zuzarte-Luis

Publikováno v: Cell Metabolism

Several vacuolar bacteria and parasites, such as Legionella, Chlamydia, and Toxoplasma, have been reported to grow associated with host mitochondria. The reason behind this phenomenon remains elusive. In this issue of Cell Metabolism, Pernas et al. (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8ba5dfd8f15591dbbd189eb218e433
https://pubmed.ncbi.nlm.nih.gov/29617646

Innate Immunity to Malaria

Autor: Anton Götz, Vanessa Zuzarte-Luis, Ana Rodriguez, Angelo Chora, Maria M. Mota, Maureen C. Ty

Publikováno v: Malaria ISBN: 9783319452081

The innate immune response to malaria has always attracted the interest of researchers trying to understand the basis for the high fevers observed in malaria patients during blood-stage infection and the lack of an apparent response to the liver-stag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87cf75225eb075d81ebaef8635770e75
https://doi.org/10.1007/978-3-319-45210-4_1