Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vanessa Yuk Man Lam"'
Autor:
Jay B. Lusk, Ellora Hui Zhen Chua, Prameet Kaur, Isabelle Chiao Han Sung, Wen Kin Lim, Vanessa Yuk Man Lam, Nathan Harmston, Nicholas S. Tolwinski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, w
Externí odkaz:
https://doaj.org/article/dfb761956de44fe5ad80f4623742e7b2
Autor:
Chu Hsien Lim, Prameet Kaur, Emelyne Teo, Vanessa Yuk Man Lam, Fangchen Zhu, Caroline Kibat, Jan Gruber, Ajay S Mathuru, Nicholas S Tolwinski
Publikováno v:
eLife, Vol 9 (2020)
The brains of Alzheimer’s disease patients show a decrease in brain mass and a preponderance of extracellular Amyloid-β plaques. These plaques are formed by aggregation of polypeptides that are derived from the Amyloid Precursor Protein (APP). Amy
Externí odkaz:
https://doaj.org/article/92b095df61944eb6979288e58c478d4a
Autor:
Prameet Kaur, Vanessa Yuk Man Lam, Anirudh Gautam Mannava, Jahnavi Suresh, Andreas Jenny, Nicholas S. Tolwinski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The highly conserved Wnt signaling pathway regulates cell proliferation and differentiation in vertebrates and invertebrates. Upon binding of a Wnt ligand to a receptor of the Fz family, Disheveled (Dsh/Dvl) transduces the signal during cano
Externí odkaz:
https://doaj.org/article/f0b54aded1a04e80b4c93f85536b5bf0
Autor:
Jay B. Lusk, Ellora Hui Zhen Chua, Prameet Kaur, Isabelle Chiao Han Sung, Wen Kin Lim, Vanessa Yuk Man Lam, Nathan Harmston, Nicholas S. Tolwinski
Publikováno v:
Scientific reports. 12(1)
Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, while the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d038db985208c37ce93eb31e8c20b4e
https://pubmed.ncbi.nlm.nih.gov/35538124
https://pubmed.ncbi.nlm.nih.gov/35538124
Autor:
Nicholas S. Tolwinski, Wen Kin Lim, Nathan Harmston, Vanessa Yuk Man Lam, Jay B Lusk, Prameet Kaur, Ellora Hui Zhen Chua, Isabelle Chiao Han Sung
Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, while the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9744a9990fd4efa721c4844850f5f3d
https://doi.org/10.1101/2021.07.29.454294
https://doi.org/10.1101/2021.07.29.454294
Autor:
Ce-Belle Chen, Kee Chee Soo, Frank Watt, Thomas Osipowicz, Zhaohong Mi, Andrew A. Bettiol, Hong Qi Tan, Ye Tao, Vanessa Yuk Man Lam
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 456:26-31
A new beam line facility dedicated to investigations into the radiobiology of biological single cells has been constructed at the Centre for Ion Beam Applications, National University of Singapore. This facility, which has a horizontal layout, has so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5789c95e87a7c39d27fce22636bfa7df
https://doi.org/10.1016/j.nimb.2019.06.038
https://doi.org/10.1016/j.nimb.2019.06.038
Autor:
Nicholas S. Tolwinski, Chu Hsien Lim, Prameet Kaur, Jan Gruber, Caroline Kibat, Vanessa Yuk Man Lam, Fangchen Zhu, Emelyne Teo, Ajay S. Mathuru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998e4e8a53f1867fd07ff348635270a8
https://doi.org/10.7554/elife.52589.sa2
https://doi.org/10.7554/elife.52589.sa2
Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model
Autor:
Vanessa Yuk Man Lam, Jan Gruber, Barry Halliwell, Keith Hsiu Chin Lim, Li Fang Ng, Li-Theng Ng, Cheryl Y.W. Huang, Irwin K. Cheah, Fang‐Qin Goh
Publikováno v:
FEBS lettersReferences. 593(16)
The abnormal accumulation of β-amyloid peptide (Aβ) is recognized as a central component in the pathogenesis of Alzheimer disease. While many aspects of Aβ-mediated neurotoxicity remain elusive, Aβ has been associated with numerous underlying pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d848ffe54bef629d49736f0b10d07f9
https://pubmed.ncbi.nlm.nih.gov/31211853
https://pubmed.ncbi.nlm.nih.gov/31211853
Autor:
Linfan Xiao, Vanessa Yuk Man Lam, Li Fang Ng, Krishna Chaithanya Batchu, Diogo Barardo, Jan Gruber, Markus R. Wenk, Tesfahun Dessale Admasu, Nicholas S. Tolwinski, Amaury Cazenave-Gassiot
Publikováno v:
Developmental cell. 47(1)
Summary There is growing interest in pharmacological interventions directly targeting the aging process. Pharmacological interventions against aging should be efficacious when started in adults and, ideally, repurpose existing drugs. We show that dra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f028f17798b113e578975f5739b98dc
https://pubmed.ncbi.nlm.nih.gov/30269951
https://pubmed.ncbi.nlm.nih.gov/30269951
Autor:
Ng Li Fang, Tesfahun Dessale, Krishna Batchu, Markus R. Wenk, Nicholas S. Tolwinski, Amaury Cazenave-Gassiot, Jan Gruber, Linfan Xiao, Vanessa Yuk Man Lam, Diogo Barardo
Publikováno v:
SSRN Electronic Journal.
Development of efficacious pharmacological interventions capable of modulating the ageing process would result in extension of human healthspan with dramatic medical and economic benefits. Such interventions would need to be efficacious even when sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3497f4e1169dcf3f33cd1b79a87994
https://doi.org/10.2139/ssrn.3188391
https://doi.org/10.2139/ssrn.3188391