Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vanessa V Sarathy"'
Autor:
Gregg N Milligan, Vanessa V Sarathy, Ernesto Infante, Li Li, Gerald A Campbell, P Robert Beatty, Eva Harris, Alan D T Barrett, Nigel Bourne
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125476 (2015)
Dengue is a mosquito-borne disease of global public health significance that is caused by four serologically and genetically related viruses (DENV-1 to DENV-4). Most human DENV infections are asymptomatic, but clinical cases can range in severity fro
Externí odkaz:
https://doaj.org/article/ecbc5b4f2c6b4fecbcf52264b3055192
Autor:
Awadalkareem Adam, Camila R. Fontes-Garfias, Vanessa V. Sarathy, Yang Liu, Huanle Luo, Emily Davis, Wenqian Li, Antonio E. Muruato, Binbin Wang, Renat Ahatov, Yoseph Mahmoud, Chao Shan, Samantha R. Osman, Steven G. Widen, Alan D. T. Barrett, Pei-Yong Shi, Tian Wang
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants,
Externí odkaz:
https://doaj.org/article/f28c37c48ce34bfaad88626bc97d5974
Autor:
Natalie D. Collins, Steven G. Widen, Li Li, Daniele M. Swetnam, Pei-Yong Shi, Robert B. Tesh, Vanessa V. Sarathy
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1126-1138 (2019)
ABSTRACTZika virus (ZIKV) strains belong to the East African, West African, and Asian/American phylogenetic lineages. RNA viruses, like ZIKV, exist as populations of genetically-related sequences whose heterogeneity may impact viral fitness, evolutio
Externí odkaz:
https://doaj.org/article/4906078e1ef94845ac324cb1a7a361ee
Autor:
Emily H. Davis, Binbin Wang, Mellodee White, Yan-Jang S. Huang, Vanessa V. Sarathy, Tian Wang, Nigel Bourne, Stephen Higgs, Alan D. T. Barrett
Publikováno v:
npj Vaccines. 7
The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection. In contr
Autor:
Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D. Barrett, Sujan Shresta, Michael S. Diamond
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice tha
Externí odkaz:
https://doaj.org/article/27a57dee613941a18b597207c172d473
Autor:
Emily H, Davis, Binbin, Wang, Mellodee, White, Yan-Jang S, Huang, Vanessa V, Sarathy, Tian, Wang, Nigel, Bourne, Stephen, Higgs, Alan D T, Barrett
Publikováno v:
NPJ vaccines. 7(1)
The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection. In contr
Autor:
Wenqian Li, Camila R. Fontes-Garfias, Yang Liu, Yoseph Mahmoud, Vanessa V. Sarathy, Steven G. Widen, Binbin Wang, Pei Yong Shi, Tian Wang, Chao Shan, Huanle Luo, Alan D.T. Barrett, Emily H. Davis, Samantha R. Osman, Awadalkareem Adam, Antonio E. Muruato, Renat Ahatov
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants, each of
Autor:
David H. Walker, Vanessa V. Sarathy
Publikováno v:
Am J Trop Med Hyg
Nine criteria regarding the infectious agent, mode of transmission, portal of entry, route of spread, target organs, target cells, pathologic lesions, incubation period, and modifiable spectrum of disease and outcomes appropriate to the intended expe
Autor:
Pei Yong Shi, Natalie D. Collins, Chao Shan, Bruno Tardelli Diniz Nunes, Alan D.T. Barrett, Steven G. Widen, Vanessa V. Sarathy
Publikováno v:
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
Vaccines, Vol 8, Iss 161, p 161 (2020)
Vaccines
Instituto Evandro Chagas (IEC)
instacron:IEC
Vaccines, Vol 8, Iss 161, p 161 (2020)
Vaccines
This research was funded in part by a Gillson-Longenbaugh Foundation grant to A.D.T.B. P.-Y.S. was supported in part by NIH grants AI142759, AI145617, AI127744, AI136126, and UL1TR001439, and awards from the Kleberg Foundation, John S. Dunn Foundatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2128dd9c41a1467460728f7ce5b3212
Autor:
Camila R. Fontes-Garfias, Yuejin Liang, Nigel Bourne, Zengguo Cao, Awadalkareem Adam, Guangyu Li, Cody Teleki, Vanessa V. Sarathy, Huanle Luo, Evandro R. Winkelmann, Jiaren Sun, Alan D.T. Barrett, Pei Yong Shi, Tian Wang, Chao Shan
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-10 (2019)
NPJ Vaccines
NPJ Vaccines
Live attenuated vaccines (LAVs) are one of the most important strategies to control flavivirus diseases. The flavivirus nonstructural (NS) 4B proteins are a critical component of both the virus replication complex and evasion of host innate immunity.