Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Vanessa V Santos"'
Autor:
Jacqueline A Bayliss, Moyra B Lemus, Vanessa V Santos, Minh Deo, Jeffrey S Davies, Bruce E Kemp, John D Elsworth, Zane B Andrews
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159381 (2016)
Metformin is a widely prescribed drug used to treat type-2 diabetes, although recent studies show it has wide ranging effects to treat other diseases. Animal and retrospective human studies indicate that Metformin treatment is neuroprotective in Park
Externí odkaz:
https://doaj.org/article/b85dfa8a090c4b9bbecfce5a0ac911cc
Autor:
Romana Stark, Owain W. Howell, Fionnuala Johnston, Mathieu Méquinion, David J. Burn, Martina Sassi, Luke D. Roberts, Zane B. Andrews, Alexander Reichenbach, Vanessa V. Santos, Luke Buntwal, Amanda K. E. Hornsby, Timothy N. C. Wells, Jeffrey S. Davies, Mario Siervo, Sarah Kathleen Haas Lockie, Alwena H. Morgan, Maria Carla Carisi
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100120-(2020)
Cell Reports. Medicine
Cell Reports. Medicine
Summary Blood-borne factors regulate adult hippocampal neurogenesis and cognition in mammals. We report that elevating circulating unacylated-ghrelin (UAG), using both pharmacological and genetic methods, reduced hippocampal neurogenesis and plastici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537086609ad66343f3808fd1cdc8ef39
https://cronfa.swan.ac.uk/Record/cronfa55678/Download/55678__18674__034ac5116f144be6b7513fa7514dd92c.pdf
https://cronfa.swan.ac.uk/Record/cronfa55678/Download/55678__18674__034ac5116f144be6b7513fa7514dd92c.pdf
Autor:
Bruce E. Kemp, Jacqueline Bayliss, Moyra B Lemus, Zane B. Andrews, Romana Stark, Sandra Galic, Daniel J. Rees, Vanessa V. Santos, Aiysha Thompson, John D. Elsworth, Jeffrey S. Davies
Publikováno v:
The Journal of Neuroscience. 36:3049-3063
Calorie restriction (CR) is neuroprotective in Parkinson's disease (PD) although the mechanisms are unknown. In this study we hypothesized that elevated ghrelin, a gut hormone with neuroprotective properties, during CR prevents neurodegeneration in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd49570a265a03ad3684044afb3a495
https://doi.org/10.1523/jneurosci.4373-15.2016
https://doi.org/10.1523/jneurosci.4373-15.2016
Autor:
Zane B. Andrews, Alexander Reichenbach, Vanessa V. Santos, David J. Burn, Romana Stark, Timothy N. C. Wells, Jeffrey S. Davies, Mario Siervo, Amanda K. E. Hornsby, Fionnuala Johnston, Luke D. Roberts
Blood-borne factors regulate adult hippocampal neurogenesis (AHN) and cognition in mammals, albeit via mechanisms that are poorly understood. We report that elevating circulating unacylated-ghrelin (UAG), using both pharmacological and genetic method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5905e98e12563a0ea0436d05fc794bbb
https://doi.org/10.1101/259333
https://doi.org/10.1101/259333
Autor:
Sarah J. Spencer, Sarah Kathleen Haas Lockie, Tamas Kozicz, Jacqueline Bayliss, Alexander Reichenbach, Romana Stark, Agustina Cabral, Mario Perello, Moyra B Lemus, Tara Dinan, Vanessa V. Santos, Zane B. Andrews, Bram Geenen
Publikováno v:
Endocrinology, 157, 3946-3957
Endocrinology, 157, 10, pp. 3946-3957
Endocrinology, 157, 10, pp. 3946-3957
Ghrelin exists in two forms in circulation, acyl ghrelin and des-acyl ghrelin, both of which have distinct and fundamental roles in a variety of physiological functions. Despite this fact, a large proportion of papers simply measure and refer to plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440a71444ea27b8a10960473d5102f40
http://hdl.handle.net/2066/167714
http://hdl.handle.net/2066/167714
Autor:
Zane B. Andrews, Moyra B Lemus, John D. Elsworth, Vanessa V. Santos, M. Deo, Jacqueline A. Bayliss
Publikováno v:
Journal of Neurochemistry
The gut hormone ghrelin is widely beneficial in many disease states. However, ghrelin exists in two distinctive isoforms, each with its own metabolic profile. In Parkinson's Disease (PD) acylated ghrelin administration is neuroprotective, however, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788c33652122f57006cd93fa8efbe470
https://pubmed.ncbi.nlm.nih.gov/26872221
https://pubmed.ncbi.nlm.nih.gov/26872221
Autor:
Sarah Kathleen Haas Lockie, Vanessa V. Santos, Alexander Reichenbach, Romana Stark, Zane B. Andrews, Jacqueline Bayliss, Moyra B Lemus
Publikováno v:
Endocrinology. 156(5)
The hypothalamic arcuate nucleus (ARC) contains 2 key neural populations, neuropeptide Y (NPY) and proopiomelanocortin (POMC), and, together with orexin neurons in the lateral hypothalamus, plays an integral role in energy homeostasis. However, no st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91ee112385192295321943fff5dadb2
https://pubmed.ncbi.nlm.nih.gov/25742051
https://pubmed.ncbi.nlm.nih.gov/25742051
Autor:
Giordano Gubert Viola, Cláudia Beatriz Nedel Mendes-de-Aguiar, Rui Daniel Prediger, Karen Andrinéia de Oliveira, Carla I. Tasca, Samuel Vandresen-Filho, Alessandra Antunes dos Santos, Vanessa V. Santos, Marcelo Farina, Tharine Dal-Cim, Wagner C. Martins
Publikováno v:
Neurotoxicity research. 28(1)
Deposition of amyloid-β (Aβ) peptides into specific encephalic structures has been pointed as an important event related to Alzheimer's disease pathogenesis and associated with activation of glial cells, neuroinflammation, oxidative responses, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9c0f6ac30e903469d085f673698576
https://pubmed.ncbi.nlm.nih.gov/25827781
https://pubmed.ncbi.nlm.nih.gov/25827781
Publikováno v:
In vivo (Athens, Greece). 18(5)
The kinetics of systemic responses triggered by bacterial peritonitis were analysed in the blood, bronchoalveolar lavage (BAL) and several organs.The murine model of cecal ligation and puncture was employed. The parameters were analysed at different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dc4551f14af278e766197ed28b83c39
https://pubmed.ncbi.nlm.nih.gov/15523895
https://pubmed.ncbi.nlm.nih.gov/15523895
Autor:
Amanda K.E. Hornsby, Luke Buntwal, Maria Carla Carisi, Vanessa V. Santos, Fionnuala Johnston, Luke D. Roberts, Martina Sassi, Mathieu Mequinion, Romana Stark, Alex Reichenbach, Sarah H. Lockie, Mario Siervo, Owain Howell, Alwena H. Morgan, Timothy Wells, Zane B. Andrews, David J. Burn, Jeffrey S. Davies
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100120- (2020)
Summary: Blood-borne factors regulate adult hippocampal neurogenesis and cognition in mammals. We report that elevating circulating unacylated-ghrelin (UAG), using both pharmacological and genetic methods, reduced hippocampal neurogenesis and plastic
Externí odkaz:
https://doaj.org/article/bbc0f91e9dda486a9282f158d171396c