Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vanessa V, Sarathy"'
Autor:
Emily H. Davis, Binbin Wang, Mellodee White, Yan-Jang S. Huang, Vanessa V. Sarathy, Tian Wang, Nigel Bourne, Stephen Higgs, Alan D. T. Barrett
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection.
Externí odkaz:
https://doaj.org/article/4ee6fe4ce2b546e084696649d0429271
Autor:
Awadalkareem Adam, Camila R. Fontes-Garfias, Vanessa V. Sarathy, Yang Liu, Huanle Luo, Emily Davis, Wenqian Li, Antonio E. Muruato, Binbin Wang, Renat Ahatov, Yoseph Mahmoud, Chao Shan, Samantha R. Osman, Steven G. Widen, Alan D. T. Barrett, Pei-Yong Shi, Tian Wang
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Abstract Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants,
Externí odkaz:
https://doaj.org/article/f28c37c48ce34bfaad88626bc97d5974
Autor:
Natalie D. Collins, Steven G. Widen, Li Li, Daniele M. Swetnam, Pei-Yong Shi, Robert B. Tesh, Vanessa V. Sarathy
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1126-1138 (2019)
ABSTRACTZika virus (ZIKV) strains belong to the East African, West African, and Asian/American phylogenetic lineages. RNA viruses, like ZIKV, exist as populations of genetically-related sequences whose heterogeneity may impact viral fitness, evolutio
Externí odkaz:
https://doaj.org/article/4906078e1ef94845ac324cb1a7a361ee
Autor:
Natalie D. Collins, Chao Shan, Bruno T.D. Nunes, Steven G. Widen, Pei-Yong Shi, Alan D.T. Barrett, Vanessa V. Sarathy
Publikováno v:
Vaccines, Vol 8, Iss 2, p 161 (2020)
Zika virus (ZIKV) is a mosquito-transmitted positive-sense RNA virus in the family Flaviviridae. Candidate live-attenuated vaccine (LAV) viruses with engineered deletions in the 3’ untranslated region (UTR) provide immunity and protection in animal
Externí odkaz:
https://doaj.org/article/1878b86feb3c4b2abf63415ec6c659d3
Autor:
Li Li, Natalie D. Collins, Steven G. Widen, Emily H. Davis, Jaclyn A. Kaiser, Mellodee M. White, M. Banks Greenberg, Alan D.T. Barrett, Nigel Bourne, Vanessa V. Sarathy
Publikováno v:
Vaccines, Vol 7, Iss 3, p 93 (2019)
Zika virus (ZIKV) is a mosquito-borne Flavivirus. Previous studies have shown that mosquito-transmitted flaviviruses, including yellow fever, Japanese encephalitis, and West Nile viruses, could be attenuated by serial passaging in human HeLa cells.
Externí odkaz:
https://doaj.org/article/ff78d027022b403db9425a6be611c40d
Autor:
Amelia K. Pinto, James D. Brien, Chia-Ying Kao Lam, Syd Johnson, Cindy Chiang, John Hiscott, Vanessa V. Sarathy, Alan D. Barrett, Sujan Shresta, Michael S. Diamond
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice tha
Externí odkaz:
https://doaj.org/article/27a57dee613941a18b597207c172d473
Autor:
Gregg N Milligan, Vanessa V Sarathy, Ernesto Infante, Li Li, Gerald A Campbell, P Robert Beatty, Eva Harris, Alan D T Barrett, Nigel Bourne
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125476 (2015)
Dengue is a mosquito-borne disease of global public health significance that is caused by four serologically and genetically related viruses (DENV-1 to DENV-4). Most human DENV infections are asymptomatic, but clinical cases can range in severity fro
Externí odkaz:
https://doaj.org/article/ecbc5b4f2c6b4fecbcf52264b3055192
Autor:
Emily H, Davis, Binbin, Wang, Mellodee, White, Yan-Jang S, Huang, Vanessa V, Sarathy, Tian, Wang, Nigel, Bourne, Stephen, Higgs, Alan D T, Barrett
Publikováno v:
NPJ vaccines. 7(1)
The envelope (E) protein of flaviviruses is functionally associated with viral tissue tropism and pathogenicity. For yellow fever virus (YFV), viscerotropic disease primarily involving the liver is pathognomonic for wild-type (WT) infection. In contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24cd42e29ddef752ae81ed15fe45c94d
https://pubmed.ncbi.nlm.nih.gov/35322047
https://pubmed.ncbi.nlm.nih.gov/35322047
Autor:
Wenqian Li, Camila R. Fontes-Garfias, Yang Liu, Yoseph Mahmoud, Vanessa V. Sarathy, Steven G. Widen, Binbin Wang, Pei Yong Shi, Tian Wang, Chao Shan, Huanle Luo, Alan D.T. Barrett, Emily H. Davis, Samantha R. Osman, Awadalkareem Adam, Antonio E. Muruato, Renat Ahatov
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
npj Vaccines, Vol 6, Iss 1, Pp 1-11 (2021)
Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants, each of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e811425d45421a0cf0d238c38d66ec38
http://europepmc.org/articles/PMC7889622
http://europepmc.org/articles/PMC7889622
Autor:
David H. Walker, Vanessa V. Sarathy
Publikováno v:
Am J Trop Med Hyg
Nine criteria regarding the infectious agent, mode of transmission, portal of entry, route of spread, target organs, target cells, pathologic lesions, incubation period, and modifiable spectrum of disease and outcomes appropriate to the intended expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e841ecdff768d72e3e52012826abba
https://pubmed.ncbi.nlm.nih.gov/32602433
https://pubmed.ncbi.nlm.nih.gov/32602433