Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vanessa S. Cull"'
Autor:
Robyn Starr, Mohinder Sarna, Samantha J Busfield, Winald Lepere, S. Peter Klinken, Melissa S. Sayer, Warren S. Alexander, Thomas Bittorf, Evan Ingley, Michael J Wright, Vanessa S. Cull, Douglas J. Hilton, David J. McCarthy, David Chappell, Peta A. Tilbrook, Stephanie S. Watowich, Gene A. Palmer
Publikováno v:
Oncogene. 22:3221-3230
The SOCS family of genes are negative regulators of cytokine signalling with SOCS-1 displaying tumor suppressor activity. SOCS-1, CIS and SOCS-3 have been implicated in the regulation of red blood cell production. In this study, a detailed examinatio
Optimization of Naked DNA Delivery for Interferon Subtype Immunotherapy in Cytomegalovirus Infection
Autor:
Josephine P. Mansfield, Emmalene J. Bartlett, Eva N. Mowe, Cassandra M. James, Vanessa S. Cull
Publikováno v:
Biological Procedures Online, Vol 5, Iss 1, Pp 43-52 (2003)
Biological Procedures
Biological Procedures
Type I interferon (IFN) gene therapy modulates the immune response leading to inflammatory heart disease following cytomegalovirus (CMV) infection in a murine model of post-viral myocarditis. Efficacy of different immunisation protocols for the IFN c
Autor:
Daniel J.J. Carr, James F. Papin, Vanessa S. Cull, Peter Härle, Ling Guo, Cassandra M. Lawson
Publikováno v:
Antiviral Research. 56:39-49
Type I interferons (IFN) constitute one of the initial and most potent components of the innate immune response against viral infections. While there is only one IFN-beta gene, there are several IFN-alpha genes whose products act through the same rec
Publikováno v:
Gene Therapy. 9:1369-1378
Viral DNA vaccines encoding the glycoprotein B (gB) of cytomegalovirus provide partial protective immunity upon challenge with infectious virus. Although it is known that type I IFN can stimulate the adaptive immune response, their direct use in vacc
Publikováno v:
Immunology. 106:428-437
Type I interferons (IFNs) are produced early in response to viral infection and modulate adaptive immunity. Previously we demonstrated localized protection against murine cytomegalovirus (MCMV) infection in IFN DNA-inoculated mice. Here we examine th
Autor:
Mohinder Sarna, David Chappell, Evan Ingley, T. Norman Palmer, Peta A. Tilbrook, Aini S Adenan, S. Peter Klinken, Stephanie S Watowich, Vanessa S. Cull
Publikováno v:
Oncogene. 19:953-960
J2E cells produce rapid, fatal erythroleukemias in vivo but still respond to erythropoietin (epo) in vitro by differentiating, proliferating and remaining viable in the absence of serum. Mutant epo receptors were introduced into these cells to determ
Publikováno v:
Methods in molecular medicine. 116
Delivery of type I interferon (IFN) subtypes by intramuscular inoculation of mice with a recombinant mammalian expression vector encoding IFN stimulates the immune response. Such immunomodulation drives towards a Th1-like response. The degree of stim
Publikováno v:
Interferon Methods and Protocols ISBN: 9781588294180
Delivery of type I interferon (IFN) subtypes by intramuscular inoculation of mice with a recombinant mammalian expression vector encoding IFN stimulates the immune response. Such immunomodulation drives towards a Th1-like response. The degree of stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810865f382ed5bbc0be29cc33ab7e470
https://doi.org/10.1385/1-59259-939-7:207
https://doi.org/10.1385/1-59259-939-7:207
Autor:
Josephine P. Mansfield, Cassandra M. James, Jason C Lenzo, Vanessa S. Cull, Soruba Sivamoorthy, Emmalene J. Bartlett
Publikováno v:
Immunology and cell biology. 82(2)
Gene therapy using DNA encoding type I IFN subtypes IFNA6, IFNA9 and IFNB suppresses murine cytomegalovirus (MCMV)-myocarditis, a predominantly cell-mediated disease in BALB/c mice. CD8(+) T cells are the principal cell type within the inflamed myoca
Autor:
Josephine P. Mansfield, Soruba Sivamoorthy, Cassandra M. James, Jason C Lenzo, Vanessa S. Cull
Publikováno v:
Cellular immunology. 223(1)
Cytomegalovirus-induced myocarditis is largely immune-mediated. BALB/c mice produced higher levels of IL-4 in the heart indicative of a Th2-like response. Although IL-6, IL-10, IL-18, and TNF-alpha were produced in the heart during acute infection, B