Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Vanessa Redecke"'
Autor:
Vanessa Redecke, Kazuki Tawaratsumida, Erin T. Larragoite, Elizabeth S. C. P. Williams, Vicente Planelles, Adam M. Spivak, Lincoln Hirayama, Marc Elgort, Shane Swenson, Rick Smith, Bryan Worthen, Russ Zimmerman, Patricia Slev, Ben Cahoon, Mark Astill, Hans Häcker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Diagnostic tests that detect antibodies (AB) against SARS-CoV-2 for evaluation of seroprevalence and guidance of health care measures are important tools for managing the COVID-19 pandemic. Current tests have certain limitations with regard
Externí odkaz:
https://doaj.org/article/1655f619167244489c5e59a7785e3869
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003727 (2013)
Streptococcus pneumoniae infection is a leading cause of bacterial pneumonia, sepsis and meningitis and is associated with high morbidity and mortality. Type I interferon (IFN-I), whose contribution to antiviral and intracellular bacterial immunity i
Externí odkaz:
https://doaj.org/article/2fba4f496af54d92a578a2b456dc1feb
A phospho-tyrosine-based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity
Autor:
Kazuki Tawaratsumida, Vanessa Redecke, Ruiqiong Wu, Jeeba Kuriakose, Jill J. Bouchard, Tanja Mittag, Brian K. Lohman, Ashutosh Mishra, Anthony A. High, Hans Häcker
Publikováno v:
Science advances. 8(27)
Toll-like receptors (TLRs) recognize pathogen- and host-derived factors and control immune responses via the adaptor protein MyD88 and members of the interferon regulatory transcription factor (IRF) family. IRFs orchestrate key effector functions, in
Autor:
Elizabeth S. C. P. Williams, Shane Swenson, Mark E. Astill, Patricia R. Slev, Vanessa Redecke, Bryan Worthen, Marc G. Elgort, Kazuki Tawaratsumida, Richard Smith, Adam M. Spivak, Ben Cahoon, Russ Zimmerman, Erin T. Larragoite, Vicente Planelles, Lincoln Hirayama, Hans Haecker
Publikováno v:
Research Square
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Diagnostic tests that detect antibodies (AB) against SARS-CoV-2 for evaluation of seroprevalence and guidance of health care measures are important tools for managing the COVID-19 pandemic. Current tests have certain limitations with regard to turnar
Autor:
Peter Vogel, Cliff Guy, Heather Tillman, Patrick D. Walker, Hans Häcker, Jeeba Kuriakose, Sirish K. Ippagunta, Vanessa Redecke, Jingran Zhou, Ruiqiong Wu
Publikováno v:
Journal of Clinical Investigation. 129:2251-2265
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with genetic and environmental contributions. Hallmarks of the disease are the appearance of immune complexes (IC) containing autoreactive Abs and TLR-activating nucleic acids, whose
Autor:
Sirish K. Ippagunta, Hans Häcker, Julie A. Pollock, John A. Katzenellenbogen, Vanessa Redecke, Naina Sharma
Publikováno v:
ChemMedChem. 13:2208-2216
The immune system uses members of the toll-like receptor (TLR) family to recognize a variety of pathogen- and host-derived molecules in order to initiate immune responses. Although TLR-mediated, pro-inflammatory immune responses are essential for hos
Publikováno v:
Immunology. 148:216-226
SHARPIN is an essential component of the linear ubiquitin chain assembly complex (LUBAC) complex that controls signalling pathways of various receptors, including the tumour necrosis factor receptor (TNFR), Toll-like receptor (TLR) and antigen recept
Autor:
Hans Häcker, Julie A. Pollock, Wenwei Lin, Taosheng Chen, Vanessa Redecke, Yizhe Chen, R. Kiplin Guy, Sirish K. Ippagunta, Naina Sharma, Kazuki Tawaratsumida, Jaeki Min, Anthony A. High, John A. Katzenellenbogen
Publikováno v:
Sci Signal
Toll-like receptors (TLRs) recognize various pathogen- and host tissue-derived molecules and initiate inflammatory immune responses. Exaggerated or prolonged TLR activation, however, can promote etiologically diverse diseases, such as bacterial sepsi
Autor:
Anthony A. High, Hans Häcker, Richard J. Webby, Vanessa Redecke, Van Phan, Eike R. Hrincius, Kazuki Tawaratsumida
Publikováno v:
Journal of Virology. 88:9038-9048
Influenza A virus (IAV) replication depends on the interaction of virus proteins with host factors. The viral nonstructural protein 1 (NS1) is essential in this process by targeting diverse cellular functions, including mRNA splicing and translation,
Autor:
Hans Häcker, Peter Vogel, Vanessa Redecke, Sirish K. Ippagunta, Ruchika Gangwar, David Finkelstein, Stephane Pelletier, Sebastien Gingras
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(41)
Psoriasis is a chronic inflammatory skin disease with a clear genetic contribution, characterized by keratinocyte proliferation and immune cell infiltration. Various closely interacting cell types, including innate immune cells, T cells, and keratino