Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vanessa Pittol"'
Autor:
Vanessa Pittol, Kleyton Santos Veras, Samuel Kaiser, Letícia Jacobi Danielli, Alexandre Meneghello Fuentefria, George González Ortega
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Poorly water-soluble drugs, such as the antifungal drug griseofulvin (GF), exhibit limited bioavailability, despite their high membrane permeability. Several technological approaches have been proposed to enhance the water solubility and bio
Externí odkaz:
https://doaj.org/article/0d49f09edb2c4d01ad2b105e925dade3
Autor:
Kleyton Santos Veras, Flávia Nathiely Silveira Fachel, Vanessa Pittol, Keth Ribeiro Garcia, Valquíria Linck Bassani, Venina dos Santos, Amélia Teresinha Henriques, Helder Ferreira Teixeira, Letícia Scherer Koester
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 8, Pp 1138-1145 (2019)
Rosmarinic acid (RA) is a phenolic compound that presents well-documented anti-inflammatory, antioxidant and antitumor activities, and based on its pharmacological potential and poor bioavailability, several solid dosage forms have been developed to
Externí odkaz:
https://doaj.org/article/1b75c53e56ae499bafba73b545d46d9c
Autor:
Pedro Ernesto de Resende, Samuel Kaiser, Vanessa Pittol, Ana Lúcia Hoefel, Raquel D'Agostini Silva, Cláudia Vieira Marques, Luiz Carlos Kucharski, George González Ortega
Publikováno v:
Journal of Functional Foods, Vol 15, Iss , Pp 440-451 (2015)
The influence of yerba mate extract (YME) and two concentrated fractions of methylxanthines–polyphenols (MXPL) and saponins (SFL) from yerba mate on the lipid metabolism of Wistar rats fed with a high-fat diet were examined. A Box–Behnken design
Externí odkaz:
https://doaj.org/article/6517ed8ecd8a464e8aa6942184c75fb1
Autor:
Evelyn Maribel Condori Peñaloza, Samuel Kaiser, Pedro Ernesto de Resende, Vanessa Pittol, Ânderson Ramos Carvalho, George González Ortega
Publikováno v:
Química Nova, Vol 38, Iss 3, Pp 378-386 (2015)
Uncaria tomentosa (cat's claw) is a vine widely distributed throughout the South-American rainforest. Many studies investigating the chemical composition of cat's claw have focused on the pentacyclic (POA) and tetracyclic oxindole alkaloids (TOA), qu
Externí odkaz:
https://doaj.org/article/d746a5e8e98f4647a300a6d35b4b3f80
Autor:
Vanessa Pittol, Kleyton Santos Veras, Eduarda Doneda, Ariane Dorneles Silva, Maria Gabriele Delagustin, Letícia Scherer Koester, Valquíria Linck Bassani
Publikováno v:
Pharmaceutical Development and Technology. 27:625-634
The complexation of herbal constituents with cyclodextrin has been a useful tool to improve their aqueous solubility. However, the simultaneous complexation of these compounds still lacks detailed studies. The present study investigated the multicomp
Autor:
Mairique Waszczuk, Sara Elis Bianchi, Vanessa Pittol, Simony Martiny, Maria G. Delagustin, Gabriela de Carvalho Meirelles, Victorya Benes Raabe, Fábio de Souza Barbosa, Denise dos Santos Lacerda, Alex S.R. Araújo, Valquiria Linck Bassani
Publikováno v:
International Journal of Pharmaceutics. 635:122736
Autor:
Nathalya Tesch Brazil, Graziela Vargas Rigo, Roselena Silvestri Schuh, Flávia Nathiely Silveira Fachel, Tiana Tasca, Vanessa Pittol, Gilsane Lino von Poser, Bruna Medeiros-Neves, Helder Ferreira Teixeira
Publikováno v:
Planta Medica. 87:480-488
Trichomonas vaginalis causes trichomoniasis, a nonviral sexually transmitted infection with a high prevalence worldwide. Oral metronidazole is the drug of choice for the treatment of this disease, although high levels of T. vaginalis resistance to th
Autor:
Valquiria Linck Bassani, Fabrício Figueiró, Irene L. Ibañez, Tainá Kreutz, Sara Elis Bianchi, Vanessa Pittol, Fábio Klamt, Hebe Duran, Eduarda Doneda, Candelaria Bracalente, Juliete Nathali Scholl
Publikováno v:
Drug Delivery and Translational Research. 11:2151-2168
3-O-Methylquercetin (3OMQ), a natural 3-O-methylflavonoid, was isolated from Achyrocline satureioides and purified using the high-performance counter current chromatography (HPCCC) on a semi-preparative scale. High-purity 3OMQ (98%) was obtained with
Autor:
Valquiria Linck Bassani, Camila Kehl Dias, V. Ashutosh Rao, Melissa A Pegues, Sara Elis Bianchi, Francesca Mascia, Vanessa Pittol, Eduarda Doneda, Fábio Klamt
Publikováno v:
IUBMB Life. 72:2133-2145
Natural products are a valuable source of new molecules and are important for drug discovery. Many chemotherapeutics currently in clinical use were originated from natural sources and are effective cytotoxic agents. In this study, we investigated the
Autor:
Alex Sander da Rosa Araujo, Sara Elis Bianchi, Denise dos Santos Lacerda, Valquiria Linck Bassani, Mairique Waszczuk, Vanessa Pittol, Simony Martiny
Publikováno v:
Analytical methods : advancing methods and applications. 12(35)
Pterostilbene is a natural constituent with numerous preventive and therapeutic properties used for treating a wide range of human diseases. It has been isolated from blueberries in high concentrations. A versatile specific-stability indicating liqui