Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Vanessa Nomellini"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100762- (2024)
Traumatic Brain Injury (TBI) is a major cause of severe disability and death, resulting in significant health care and economic burden. Poloxamer 188, a synthetic tri-block copolymer approved by the FDA, has been studied for its potential effects on
Externí odkaz:
https://doaj.org/article/ecab3d8255d143cab5f1302d6584bd15
Autor:
Brent T. Xia, Nadine Beckmann, Leah K. Winer, Amanda M. Pugh, Timothy A. Pritts, Vanessa Nomellini, Erich Gulbins, Charles C. Caldwell
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 3, Pp 565-579 (2019)
Externí odkaz:
https://doaj.org/article/196bbfe791704a12b8a569d4dac041e8
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 5, Iss 1 (2020)
There are sparse clinical data addressing the persistence of disordered coagulation in sepsis and its role in chronic critical illness. Coagulopathy in the absence of anticoagulant therapy and/or liver disease can be highly variable in sepsis, but it
Externí odkaz:
https://doaj.org/article/ef652c8db2404cd0a636fa3909950484
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
While mortality after acute sepsis has decreased, the long-term recovery for survivors is still poor, particularly those developing persistent inflammation, immunosuppression, and catabolism syndrome (PICS). While previously thought that activated ne
Externí odkaz:
https://doaj.org/article/551fc7157120431cbe360fd2759ec565
Autor:
Nadine Beckmann, Franziska Huber, Marc Hanschen, Barbara St. Pierre Schneider, Vanessa Nomellini, Charles C. Caldwell
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Infection is a common and severe complication of burn injury: Sepsis accounts for 47% of postburn mortality. Burn-induced T cell suppression likely contributes to the increased infection susceptibility in burn patients. However, little is known about
Externí odkaz:
https://doaj.org/article/19aa9d6fee704a5b9bac001411f9e91c
Autor:
Amanda M. Pugh, Nicholas J. Auteri, Holly S. Goetzman, Charles C. Caldwell, Vanessa Nomellini
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 8, p 1741 (2017)
Critically ill patients that survive sepsis can develop a Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS), which often leads to extended recovery periods and multiple complications. Here, we utilized a cecal ligation and pu
Externí odkaz:
https://doaj.org/article/1c9c498281c047e589da7802b27003ce
Autor:
Christian R. Gomez, John Karavitis, Jessica L. Palmer, Douglas E. Faunce, Luis Ramirez, Vanessa Nomellini, Elizabeth J. Kovacs
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Here, we studied in vitro cytokine production by splenic macrophages obtained from young and aged BALB/c wild type (WT) and IL-6 knockout (IL-6 KO) mice. Relative to macrophages obtained from young WT mice given lipopolysaccharide (LPS), those from a
Externí odkaz:
https://doaj.org/article/ffd3e5ae7cea46efafafc23cd0112440
Autor:
Timothy A. Pritts, Kathleen E. Singer, Jonathan Sussman, Leah K. Winer, Resha A. Kodali, Christopher A. Droege, Dennis J. Hanseman, Michael D. Goodman, Vanessa Nomellini, Victor Heh
Publikováno v:
Journal of Surgical Research. 265:139-146
Background There is no consensus on what dose of norepinephrine corresponds with futility. The purpose of this study was to investigate the maximum infusion and cumulative doses of norepinephrine associated with survival for patients in medical and s
Autor:
Taylor E. Wallen, Nora C. Elson, Kathleen E. Singer, Hannah V. Hayes, Ann Salvator, Christopher A. Droege, Vanessa Nomellini, Timothy A. Pritts, Michael D. Goodman
Publikováno v:
The journal of trauma and acute care surgery. 93(4)
The goals of sedation in the critically ill surgical patient are to minimize pain, anxiety, and agitation without hindering cardiopulmonary function. One potential benefit of tracheostomy during endotracheal intubation is the reduction of sedation an
Autor:
Matthew N. Alder, Amy Opoka, Lin Fei, Al-Faraaz Kassam, Nick C. Levinsky, Patrick Lahni, Hector R. Wong, Jaya P Mallela, Rashmi D Sahay, Kira Angel, Vanessa Nomellini
Publikováno v:
Am J Respir Cell Mol Biol
Neutrophils are vital to both the inflammatory cascade and tissue repair after an injury. Neutrophil heterogeneity is well established but there is less evidence for significant, different functional roles for neutrophil subsets. OLFM4 (Olfactomedin-