Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vanessa M. Scanlon"'
Autor:
Vanessa M. Scanlon, Evrett N. Thompson, Betty R. Lawton, Maria Kochugaeva, Kevinminh Ta, Madeline Y. Mayday, Juliana Xavier-Ferrucio, Elaine Kang, Nicole M. Eskow, Yi-Chien Lu, Nayoung Kwon, Anisha Laumas, Matthew Cenci, Kalyani Lawrence, Katie Barden, Shannon T. Larsuel, Fiona E. Reed, Gabriela Peña-Carmona, Ashley Ubbelohde, June P. Lee, Shakthi Boobalan, Yvette Oppong, Rachel Anderson, Colby Maynard, Kaylie Sahirul, Callista Lajeune, Varsha Ivathraya, Tiffany Addy, Patricia Sanchez, Colin Holbrook, Andrew Tri Van Ho, James S. Duncan, Helen M. Blau, Andre Levchenko, Diane S. Krause
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Single-cell assays have enriched our understanding of hematopoiesis and, more generally, stem and progenitor cell biology. However, these single-end-point approaches provide only a static snapshot of the state of a cell. To observe and measu
Externí odkaz:
https://doaj.org/article/76d92c4dbeae436dbee982f2d2787526
Autor:
Vanessa M Scanlon, Karin E. Finberg, Juliana Xavier-Ferrucio, Chang Cao, Larisa Lozovatsky, Nadia Ayala-Lopez, Ping-Xia Zhang, Stephanie Halene, Xiuqi Li, Diane S. Krause, Toma Tebaldi, Mark D. Fleming
Publikováno v:
Blood. 134:1547-1557
The mechanisms underlying thrombocytosis in patients with iron deficiency anemia remain unknown. Here, we present findings that support the hypothesis that low iron biases the commitment of megakaryocytic (Mk)-erythroid progenitors (MEPs) toward the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783baa831f5a42972e4cf202cf96bd90
https://doi.org/10.1182/blood.2019002039
https://doi.org/10.1182/blood.2019002039
Autor:
Vanessa M Scanlon, Michael S. Marks, Jialing Bao, Mortimer Poncz, M. Anna Kowalska, Siying Zou, Ping-Xia Zhang, Alexandra M. Teixeira, Tarun Tyagi, Vincent Hayes, Carmen J. Booth, Diane S. Krause, John Hwa
Publikováno v:
Thrombosis and Haemostasis. 119:744-757
Cadherins play a major role in mediating cell–cell adhesion, which shares many parallels with platelet–platelet interactions during aggregate formation and clot stabilization. Platelets express epithelial (E)-cadherin, but its contribution to pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09c571e834493924e6075028c146a06
https://doi.org/10.1055/s-0039-1679908
https://doi.org/10.1055/s-0039-1679908
Publikováno v:
The Journal of Biological Chemistry
Myocardin-related transcription factor A (MRTFA) is a coactivator of serum response factor, a transcription factor that participates in several critical cellular functions including cell growth and apoptosis. MRTFA couples transcriptional regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0791b43d704c4a84c7fb802d13d40f7
http://europepmc.org/articles/PMC8079280
http://europepmc.org/articles/PMC8079280
Autor:
Vanessa M Scanlon, Nayoung Kwon, Evrett N Thompson, Madeline Y Mayday, Yi-Chien Lu, Diane S. Krause
Publikováno v:
Curr Opin Hematol
Purpose of review This review focuses on our current understanding of fate decisions in bipotent megakaryocyte-erythroid progenitors (MEPs). Although extensive research has been carried out over decades, our understanding of how MEP commit to the ery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeebb9fd0788be1b299f38822f6dbdb
https://europepmc.org/articles/PMC7737300/
https://europepmc.org/articles/PMC7737300/
Autor:
Katie Barden, Varsha Ivathraya, Tiffany Addy, Betty M Lawton, Andrew Tri Van Ho, Yi-Chien Lu, Shakthi Boobalan, Colby Maynard, Anisha Laumas, June P Lee, Helen M. Blau, Nayoung Kwon, Nicole M Eskow, Kaylie Sahirul, Diane S. Krause, Fiona Reed, Maria P. Kochugaeva, Elaine Kang, Rachel Anderson, Patricia Sanchez, Callista Lajeune, Gabriela Pena-Carmona, Andre Levchenko, Colin Holbrook, Kalyani Lawrence, Shannon M Larsuel, Matthew Cenci, Yvette Oppong, Ashley Ubbelohde, Vanessa M Scanlon, Juliana Xavier-Ferrucio
Publikováno v:
Blood. 138:3270-3270
The molecular mechanisms underlying lineage commitment of stem and progenitor cells have implications for deriving specific cell types in vitro for regenerative medicine purposes. Current approaches to derive transfusable amounts of erythrocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf24197ee281c02afc33ce1a331a93d
https://doi.org/10.1182/blood-2021-154360
https://doi.org/10.1182/blood-2021-154360
Autor:
Anupama Narla, Kathleen M. Sakamoto, Vanessa M Scanlon, Aya Shibuya, Mark C. Wilkes, Hee-Don Chae
Publikováno v:
Blood. 138:2189-2189
Diamond Blackfan Anemia (DBA) is a rare genetic disease predominantly caused by mutations carried within one of at least 20 ribosomal genes. DBA is characterized by red blood cell aplasia and normal myeloid and megakaryocyte progenitors, indicating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9da8b83475416a8bd92a81e80b3904
https://doi.org/10.1182/blood-2021-153814
https://doi.org/10.1182/blood-2021-153814
Autor:
Alan D. Friedman, Alan B. Cantor, Lin Wang, Vanessa M Scanlon, Diane S. Krause, Yi-Chien Lu, Juliana Xavier-Ferrucio
Publikováno v:
Blood. 136:15-15
Human Megakaryocytic-Erythroid Progenitors (MEP) produce megakaryocytic progenitors (MkP) and erythroid progenitors (ErP). Though some of the players have been identified, the molecular mechanisms underlying the MEP fate decision have not yet been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20e305cd88a25e76c59b1dbdb6d0f0cf
https://doi.org/10.1182/blood-2020-141156
https://doi.org/10.1182/blood-2020-141156
Autor:
Matthew Cenci, Vanessa M Scanlon, Anisha Laumas, Diane S. Krause, Helen M. Blau, Colin Holbrook, Yi-Chien Lu, Andre Levchenko, Andrew Tri Van Ho, Juliana Xavier-Ferrucio, Katie Barden, Nayoung Kwon, Maria P. Kochugaeva, Kalyani Lawrence
Publikováno v:
Blood. 134:1190-1190
The molecular mechanisms underlying lineage commitment of stem and progenitor cells have implications for deriving specific cell types in vitro for regenerative medicine purposes and elucidating the aberrant pathways responsible for pathological cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04919feb40d6898705524874a010a162
https://doi.org/10.1182/blood-2019-131204
https://doi.org/10.1182/blood-2019-131204