Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Vanessa M. Lima"'
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Akademický článek
Time-regulated transcripts with the potential to modulate human pluripotent stem cell-derived cardiomyocyte differentiation
Autor: Juan J. A. M. Muñoz, Rafael Dariolli, Caio Mateus da Silva, Elida A. Neri, Iuri C. Valadão, Lauro Thiago Turaça, Vanessa M. Lima, Mariana Lombardi Peres de Carvalho, Mariliza R. Velho, Eric A. Sobie, Jose E. Krieger
Publikováno v: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-27 (2022)
Abstract Background Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising disease model, even though hiPSC-CMs cultured for extended periods display an undifferentiated transcriptional landscape. MiRNA–target gene in
Externí odkaz: https://doaj.org/article/b25de1df4cea49079927edc93026a79a
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5
Akademický článek
A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats
Autor: Julio C. B. Ferreira, Juliane C. Campos, Nir Qvit, Xin Qi, Luiz H. M. Bozi, Luiz R. G. Bechara, Vanessa M. Lima, Bruno B. Queliconi, Marie-Helene Disatnik, Paulo M. M. Dourado, Alicia J. Kowaltowski, Daria Mochly-Rosen
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract We previously demonstrated that beta II protein kinase C (βIIPKC) activity is elevated in failing hearts and contributes to this pathology. Here we report that βIIPKC accumulates on the mitochondrial outer membrane and phosphorylates mitof
Externí odkaz: https://doaj.org/article/10da15e390414801950d6b6ca5915d4c
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7
The miRNA-143-3p-Sox6-Myh7 pathway is altered in obesogenic diet-induced cardiac hypertrophy
Autor: Tábatha de Oliveira Silva, Caroline A. Lino, Juliane B. Miranda, Camila S. Balbino‐Silva, Guilherme Lunardon, Vanessa M. Lima, Leonardo Jensen, Jose Donato, Maria Cláudia Irigoyen, Maria Luiza M. Barreto‐Chaves, Gabriela P. Diniz
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
What is the central question of this study? What is the effect of an obesogenic diet on the expression of microRNAs (miRNAs) involved in cardiac hypertrophy in female mice? What is the main finding and its importance? Female mice fed an obesogenic di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517275c226460f0130c96022c417eeed
https://pubmed.ncbi.nlm.nih.gov/35765992
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8
Set7 deletion prevents glucose intolerance and improves the recovery of cardiac function after ischemia and reperfusion in obese female mice
Autor: Juliane B, Miranda, Guilherme, Lunardon, Vanessa M, Lima, Tábatha, de Oliveira Silva, Caroline A, Lino, Leonardo, Jensen, Maria Cláudia, Irigoyen, Ivson Bezerra, da Silva, Yao Wei, Lu, Jianming, Liu, Jose, Donato Júnior, Maria Luiza M, Barreto-Chaves, Da-Zhi, Wang, Gabriela P, Diniz
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background/Aims: An obesogenic diet (high fat and sugar, low fiber) is associated with an increased risk for metabolic and cardiovascular disorders. Previous studies have demonstrated that epigenetic changes can modify gene transcription and protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d165f3b5aa40da2fd7a4117b8a0e54
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9
Akademický článek
Histomorfometria das meninges encefálicas de ratos Wistar em diferentes faixas etárias
Autor: Kleber F Pereira, Vanessa M Lima, Celso I Conegero, Renato P Chopard
Publikováno v: Pesquisa Veterinária Brasileira, Vol 30, Iss 11, Pp 996-1002 (2010)
O desenvolvimento do sistema nervoso é bastante complexo, existindo poucos estudos sobre a organização dos envoltórios cerebrais relacionados ao crescimento encefálico. Utilizando como modelo experimental o rato, analisaram-se os diferentes aspe
Externí odkaz: https://doaj.org/article/e8258900f88148d98a624d21183a79fb
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