Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Vanessa M. Hubbard-Lucey"'
Autor:
Maria L. Ascierto, Helen X. Chen, David M. Feltquate, Rachel W. Humphrey, Theresa M. LaVallee, Vanessa M. Hubbard-Lucey, Eric H. Rubin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
As the field of cancer immunotherapy continues to advance at a fast pace, treatment approaches and drug development are evolving rapidly to maximize patient benefit. New agents are commonly evaluated for activity in patients who had previously receiv
Externí odkaz:
https://doaj.org/article/89bb1f6f1879436cad94a0ed44bd3547
Autor:
Lacey J. Padrón, Deena M. Maurer, Mark H. O’Hara, Eileen M. O’Reilly, Robert A. Wolff, Zev A. Wainberg, Andrew H. Ko, George Fisher, Osama Rahma, Jaclyn P. Lyman, Christopher R. Cabanski, Jia Xin Yu, Shannon M. Pfeiffer, Marko Spasic, Jingying Xu, Pier Federico Gherardini, Joyson Karakunnel, Rosemarie Mick, Cécile Alanio, Katelyn T. Byrne, Travis J. Hollmann, Jonni S. Moore, Derek D. Jones, Marco Tognetti, Richard O. Chen, Xiaodong Yang, Lisa Salvador, E. John Wherry, Ute Dugan, Jill O’Donnell-Tormey, Lisa H. Butterfield, Vanessa M. Hubbard-Lucey, Ramy Ibrahim, Justin Fairchild, Samantha Bucktrout, Theresa M. LaVallee, Robert H. Vonderheide
Publikováno v:
Nature Medicine. 28:1167-1177
Chemotherapy combined with immunotherapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for pancreatic ductal adenocarcinoma (PDAC). We conducted a randomized phase 2 trial evaluating the efficacy of nivolum
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
Immunotherapy is rapidly becoming a standard of care for many cancers. However, colorectal cancer had been generally resistant to immunotherapy, despite features in common with sensitive tumors. Observations of substantial clinical activity for check
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe819a9579ba657dff6e159f30b6a62
https://doi.org/10.1158/2326-6066.c.6548287.v1
https://doi.org/10.1158/2326-6066.c.6548287.v1
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
Supplemental Tables 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707eae64e6122a01edf458348b5685d3
https://doi.org/10.1158/2326-6066.22536955.v1
https://doi.org/10.1158/2326-6066.22536955.v1
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
S1. Therapeutic strategies and corresponding laboratory tests.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e944f1518c8c2642c4ce5c6e4a3dc5a
https://doi.org/10.1158/2326-6066.22536961
https://doi.org/10.1158/2326-6066.22536961
Autor:
Al B. Benson, Sharyn Worrall, Keavy McAbee, Anjelica Q. Davis, Nancy Roach, Jill O'Donnell-Tormey, Edward Cha, Rebecca A. Moss, Arvin Yang, Neil H. Segal, Cynthia L. Sears, Wells Messersmith, Christopher H. Lieu, Smitha S. Krishnamurthi, S. Peter Kang, Elizabeth M. Jaffee, Franck Housseau, Stanley R. Hamilton, Richard M. Goldberg, Wolf H. Fridman, Luis A. Diaz, Dustin A. Deming, Emily Chan, Arthur N. Brodsky, Thomas H. Marsilje, Andrea Dwyer, Christopher R. Heery, Michael A. Morse, Vanessa M. Hubbard-Lucey, Dung T. Le
S2. Policy and Infrastructure driven solutions noted for support of immunology work.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b6b363331e504561bc3bff324fa86b
https://doi.org/10.1158/2326-6066.22536958
https://doi.org/10.1158/2326-6066.22536958
Autor:
Maria Karasarides, Alexandria P. Cogdill, Paul B. Robbins, Michaela Bowden, Elizabeth M. Burton, Lisa H. Butterfield, Alessandra Cesano, Christian Hammer, Cara L. Haymaker, Christine E. Horak, Heather M. McGee, Anne Monette, Nils-Petter Rudqvist, Christine N. Spencer, Randy F. Sweis, Benjamin G. Vincent, Erik Wennerberg, Jianda Yuan, Roberta Zappasodi, Vanessa M. Hubbard Lucey, Daniel K. Wells, Theresa LaVallee
Publikováno v:
Cancer immunology research, vol 10, iss 4
Immune-checkpoint inhibitors (ICI), although revolutionary in improving long-term survival outcomes, are mostly effective in patients with immune-responsive tumors. Most patients with cancer either do not respond to ICIs at all or experience disease
Autor:
Christopher R. Cabanski, Vanessa M. Hubbard-Lucey, Zev A. Wainberg, Lacey J. Kitch, Robert A. Wolff, Gauri R. Varadhachary, Ute Dugan, Theresa LaVallee, Christine Horak, Rosemarie Mick, Cécile Alanio, Samantha Bucktrout, Justin Fairchild, Mark H. O'Hara, E. John Wherry, Andrew H. Ko, Jaclyn P. Lyman, Cheryl Selinsky, Jingying Xu, Eileen M. O'Reilly, Joyson Joseph Karakunnel, George A. Fisher, Pier Federico Gherardini, Ramy Ibrahim, Ovid C. Trifan, Osama E. Rahma, Theresa Samuel, Richard O Chen, Jacob Till, Robert H. Vonderheide, Erica L. Carpenter, Katelyn T. Byrne
Summary Background Standard chemotherapy remains inadequate in metastatic pancreatic adenocarcinoma. Combining an agonistic CD40 monoclonal antibody with chemotherapy induces T-cell-dependent tumour regression in mice and improves survival. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d88be94bf2c7ba56dffa950d893e5d9
https://hdl.handle.net/2108/312077
https://hdl.handle.net/2108/312077
Autor:
Zhiqin Huang, Pramod K. Srivastava, Song Liu, Jason A. Greenbaum, Dirk Jäger, Jiaqian Wang, Ognjen Milicevic, Willem-Jan Krebber, Barbara Schrörs, Sean Michael Boyle, Michal Bassani-Sternberg, Ana M. Mijalkovic Lazic, Amit A. Lugade, Kristen K. Dang, Han Si, Alessandro Sette, Jeffrey P. Ward, Irsan Kooi, Michael F. Princiotta, Begonya Comin-Anduix, Thierry Schuepbach, Pia Kvistborg, Julia Kodysh, William Chour, Vladimir B. Kovacevic, Jan H. Kessler, Ariella Sasson, Antoni Ribas, Brian Stevenson, Sriram Sridhar, Prateek Tanden, Robert D. Schreiber, Jason Perera, Kathleen C. F. Sheehan, Hira Rizvi, Sachet A. Shukla, Baikang Pei, Han Chang, Bo Li, Ion I. Mandoiu, Cristina Puig-Saus, Beatriz M. Carreno, Si Qiu, Jennifer M. Shelton, Patrick Jongeneel, Qiang Hu, Taha Merghoub, Matthew D. Hellmann, James P. Conway, Francisco Arcila, Ton N. Schumacher, Mathias Vormehr, Christopher A. Morehouse, Patrice Manning, Jonathon Blake, Pornpimol Charoentong, Angela Frentzen, Christopher A. Miller, Michael A. Kuziora, Bin Song, Lei Wei, Martin Löwer, Gabor Bartha, Justin Guinney, Niels Halama, Rolf Hilker, Yinong Sebastian, Veliborka Josipovic, Jason Harris, Geng Liu, Guilhem Richard, Arjun A. Rao, Nikola M. Skundric, Markus Mueller, Daniel K. Wells, Tatiana Shcheglova, Inka Zörnig, Weixuan Fu, John Sidney, Nadine Defranoux, Gabriela Steiner, Joseph D. Szustakowski, Arbel D. Tadmor, Maxim N. Artyomov, Jianmin Wang, George Coukos, Brandon W. Higgs, Milica R. Kojicic, Siranush Sarkizova, Daphne van Beek, Naibo Yang, Robert Ziman, Mignonette H. Macabali, Thomas Yu, Nicolas Guex, Nina Bhardwaj, Lorenzo F. Fanchi, Bjoern Peters, Christian Iseli, Song Wu, Maren Lang, Juliet Forman, Marit M. van Buuren, David Balli, Steven L. C. Ketelaars, Nir Hacohen, Ekaterina Esaulova, Maarten Slagter, Todd Creasy, Robert A. Petit, Yi-Hsiang Hsu, Ravi Gupta, Katie M. Campbell, Pascal Gellert, David Haussler, Jesse M. Zaretsky, Sofie R. Salama, Vanessa M. Hubbard-Lucey, Joel Greshock, Zeynep Kosaloglu Yalcin, Cornelis J. M. Melief, Priyanka Shah, Ioannis Xenarios, Nevena M. Ilic Raicevic, Andrew Lamb, Suchit Jhunjhunwala, Aly A. Khan, David Gfeller, James R. Heath, Richard Chen, Jia M. Chen, Alphonsus H. C. Ng, Elham Sherafat, Ana Belen Blazquez, Leo J. Lee, Beata Berent-Maoz, Cheryl Selinsky, Jasreet Hundal, Eduardo Cortes, Xengie Doan, Sahar Al Seesi, Adam Kolom, Fred Ramsdell, Nicolas Robine, Andrew J. Rech
Many approaches to identify therapeutically relevant neoantigens couple tumor sequencing with bioinformatic algorithms and inferred rules of tumor epitope immunogenicity. However, there are no reference data to compare these approaches, and the param
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b788124c42a6ace5b9cb5efa2f3572c
https://resolver.caltech.edu/CaltechAUTHORS:20201019-121956456
https://resolver.caltech.edu/CaltechAUTHORS:20201019-121956456
Autor:
Adi Diab, Robert R Jenq, Gabrielle A Rizzuto, Adam D Cohen, Deonka W Huggins, Taha Merghoub, Manuel E Engelhorn, José A Guevara-Patiño, David Suh, Vanessa M Hubbard-Lucey, Adam A Kochman, Suzie Chen, Hong Zhong, Jedd D Wolchok, Marcel R M van den Brink, Alan N Houghton, Miguel-Angel Perales
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82496 (2013)
The development of successful cancer vaccines is contingent on the ability to induce effective and persistent anti-tumor immunity against self-antigens that do not typically elicit immune responses. In this study, we examine the effects of a non-myel
Externí odkaz:
https://doaj.org/article/7e942a7cda4b4992b7f10515a52d9625